38 results about "Radiation Pneumonitis" patented technology

A Chinese medicine in the form of decoction for treating radiopneumonia is prepared from 10 Chinese-medicinal materials including scrophularia root, rehmannia root, mint, liquorice root, etc through immersing, decocting and filtering.

The invention relates to a method for early monitoring radioactive pneumonia fibrosis caused by tumor radiotherapy, in particular to a method for early diagnosis and prognosis evaluation of radioactive pneumonia by using a molecular marker. By the design of primers S100A8 and S100A9 and antibodies of a human, generation of the radioactive pneumonia and the pulmonary fibrosis can be monitored in the early stage, and the prognosis of diseases can be estimated. The method has the advantages of simple operation, high sensitivity and high specificity.

A method for the prevention of and therapy for radiation pneumonitis, dermatitis, soft tissue fibrosis and central nervous system toxicity in patients undergoing therapeutic radiation. In addition, the invention provides for pre-treatment of those responding to nuclear bio terrorism or other nuclear or radiological accidents. Thus, with the present invention, subjects may be treated in order to prevent toxicity from nuclear bio terrorism or other nuclear or radiological accidents. More particularly, we have discovered a method for prophylactically treating radiation toxicity in normal tissue of subject comprising administering an anti-radiation toxicity effective amount of a cytokine blocking agent through the subject. More specifically, we have discovered a method for prophylactically treating radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity in a subject comprising administering an anti-radiation pneumonitis, dermatitis, soft tissue fibrosis or central nervous system toxicity effective amount of a cytokine blocking agent to the subject.

The invention relates to a traditional Chinese medicine for treating radiation pneumonia, which is characterized by being prepared from the following medicinal materials by weight: 8-12g of dangshen, 8-12g of astragalus root, 8-10g of angelica sinensis, 8-12g of radix scrophulariae, 6-8g of ophiopogon root, 6-9g of cortex phellodendri, 3-6g of plaster, 6-8g of rhizoma anemarrhenae, 4-6g of peach kernels, 6-8g of radix rehmanniae, 6-8g of tendril-leaved fritillary bulb, 6-8g f platycodon grandiflorum, 6-8g of Chinese gall, 8-10g of houttuynia cordata, 6-8g of radix paeoniae rubra, 4-6g of caulis spatholobi, 6-8g of dendrobium nobile and 3-6g of radix liquiritiae. The traditional Chinese medicine is decocted, one dose is divided to be administrated in every morning and evening, ten days is a treatment course, and drug discontinuance is carried out for two days between the two treatment courses. The radiation pneumonia is recovered by the traditional Chinese treatment, the rules of treatment are to strengthen healthy energy, tonify qi, nourish blood, nourish Yin and clear heat, moisten lung and generate a body fluid, and activate blood circulation and dispel blood stasis, and diagnosis and treatment based on overall analysis of the illness and the condition of the patient are carried out clinically. Proven by clinical application trials for many years, the traditional Chinese medicine can be used for effectively treat acute and chronic radiation pneumonia, the effective rate can achieve 91.1 percent, the recovery rate can reach 82.3 percent and no toxic and side effects exist.

The invention discloses a device and a method for non-diagnostically determining functional equivalent uniform dose of an object. The device comprises a single photon emission computed tomography device, an X-ray computed tomography system, a treatment planning system, an image processing unit and an equivalent uniform dose computing unit. The single photon emission computed tomography device is used for providing a SPECT lung perfusion image of the object. The X-ray computed tomography system is used for providing a CT image of the object. The treatment planning system is used for providing an in-vivo dose distribution condition when the object is treated with radiotherapy. The image processing unit is used for deformation and fusion of the SPECT lung perfusion image and the CT image in order to form a fusion image. The equivalent uniform dose computing unit comprises function image parameters and carries out data processing operation onto parameters of the fusion image and dose distribution of the treatment planning system, thereby acquiring functional equivalent uniform dose of the object. The functional equivalent uniform dose computed by the device and the method enjoys highersensitivity and singularity in an aspect of radiation pneumonitis prediction.

The invention discloses an astragalus polysaccharide sustained release microsphere for treating radiation pneumonitis. The astragalus polysaccharide sustained release microsphere comprises the following components in parts by weight: 1 part of astragalus polysaccharide and 3-7 parts of chitosan, wherein the degree of polymerization of chitosan is 30CPS, 50CPS and 130 CPS. The invention simultaneously discloses a preparation method of the astragalus polysaccharide sustained release microsphere. The astragalus polysaccharide sustained release microsphere prepared by virtue of the preparation method has an ideal targeting effect, can slowly release after being administrated, is long in action time and is capable of increasing the concentration of astragalus polysaccharide in target organs, and the high local blood concentration is avoided; the astragalus polysaccharide sustained release microsphere is safe and environmentally friendly and has high treatment effect to radiation pneumonitis and little side effect; the operation is simple and convenient, a process is stable, and industrial production is easily realized; the astragalus polysaccharide sustained release microsphere is high in encapsulation efficiency and drug loading capacity; the skin of a patient is smooth and fine after the administration.

The invention relates to the field of lung cancer treatment, in particular to genetic biomarkers for predicting or assisting in predicting the risk of radiation pneumonitis after pulmonary radiation,and application of the genetic biomarkers. The genetic biomarkers comprise single-nucleotide polymorphic sites from RP2-01 to RP2-31; and the group of the genetic biomarkers fills in the absence of abiomarker which can be used for predicting the risk of radiation pneumonitis after the pulmonary radiation in patients in the prior art. The group of the single-nucleotide polymorphic sites is of different genotypes in different individuals; the different genotypes can affect the sensitivity of normal lung tissues to radiation; by detecting and evaluating the sites, a prognosis can be assisted; and the genetic biomarkers are of great significance to guide the monitoring and treatment of patients with a lung cancer after radiotherapy.

The invention relates to a Chinese herba preparation for treating radiation pneumonitis. The Chinese herba preparation comprises oldenlandia diffusa, giant knotweed rhizome, mother chrysanthemum, honeysuckle, platycodon grandiflorum, pepperweed seed, dandelion, radix scrophulariae, forsythia, reed rhizome, herba lysimachiae, folium Isatidis, fructus gardeniae, dendrobium, radix curcumae, salix leaf, and musk. The Chinese herba preparation has the effects of clearing away heat and toxic materials, dispersing blood stasis and freeing lung, eliminating carbuncle and eliminating stagnation, and regulating vital energy and relieving cough. After taking, the drug is directly acted on the respiratory system, so as to improve meionectic blood, control infection, prevent lung blood capillary and arteriole from hyperaemia, expansion and embolism, and inhibit the reduction of the gas exchange function and the increase of the pulmonary artery pressure caused by the lung inside fibrosis, alveolar septum thickening, pulmonary alveoli atrophy or blood vessel wall thickening, glassy degeneration and hardening, lumen narrowing or blockage. The Chinese herba preparation reduces the blood vessel permeability, promote the respiratory system and the blood system to recovery the self-regulation function, and finally reach the purpose of healing the radiation pneumonitis.

The invention relates to radiation pneumonitis related genes ATM and P53 as well as polymorphic loci and an application thereof. An ATM gene promoter region-111G, an A mononucleotide polymorphic locus rs189037 and a functional single nucleotide polymorphism of a P53 gene coding region Arg72Pro during the single or cooperative action are related with the occurrence of radiation pneumonitis after radiation therapy. After the polymorphic loci of the ATM genes and the P53 genes of a pulmonitis patient are carried out gene typing, an individual easy to be infected with the radiation pneumonitis after radiotherapy can be identified, thus the invention can be applied to prevent the occurrence of the radiation pneumonitis.

The invention discloses a Chinese medicinal preparation for treating radiation pneumonitis. The radiation pneumonitis belongs to the categories of 'cough' and 'consumptive lung disease' considered by the traditional Chinese medicine, belongs to the evil of toxic heat burns fluid for the irradiation of the radioactive rays and harms the human body vital Qi and Yin blood; and the pathogenesis is heat toxin, Yin deficiency, Qi deficiency, phlegm dampness and blood stasis. Therefore, peristrophe, rhizoma panacis majoris, lignum dalbergiae odoriferae, chicken with yellow feet, adenophora tetraphylla, Ilex cornuta lindl, tricuspid cudrania bark, Chinese pulsatilla root, cacumen biotae, radix tetrastigme, dandelion, gynostemma pentaphyllum, callicarpa bodinieri, argentina anserine, white atractylodes rhizome and licorice are decocted by using water. Clinical experiments in the hospital prove that the total effective rate is 95.3% and the Chinese medicinal preparation is worthy of clinical popularization and application.

The invention discloses a radiation pneumonitis CT (Computed Tomography) quantitative detection method used for a radiobiology experiment. Through a CT low-dosage scanning parameter, a scanning imageis subjected to three-dimensional reconstruction, then, a CT three-dimensional segmentation image pixel histogram is obtained on the basis of an automatic region growth lung image matrix three-dimensional segmentation technology, a pneumonitis index algorithm is adopted through a pneumonitis degree quantitative criterion, and a mouse pneumonitis index is obtained to finish noninvasive quantitativedetection. The method effectively appears in noninvasive quantitative detection methods which aim at the mouse radiation pneumonitis model at home and abroad for the first time, and is an experimentdetection method which can objectively and accurately quantify the generation and the development of the mouse pneumonitis in real time, and the accuracy, the simplification, the stability and the efficiency of radiation inducibility mouse pneumonitis detection can be obviously improved. While experiment cost and vigor can be greatly reduced, the dependency of small animal minitype CT is reduced,experience cost is lowered, and the method has the obvious advantages of no trauma, high speed in scanning, high accuracy, good repeatability and the like.

The invention relates to the field of medical research, in particular to a method of building a radiation pneumonitis model. The method of building the radiation pneumonitis model comprises the following steps: (1) carrying out intravenous anesthesia on an experimental dog, and carrying out a modeling experiment when depth of anesthesia is suitable; (2) fixing the experimental dog on a CT analog body frame, choosing the right lung to carry out CT analog scanning, and transmitting an image to a radiotherapy plan system; (3) sketching the right lung, and meanwhile protecting vitals and structures of a spinal cord, a liver and a heart; (4) making an irradiation plan, setting an irradiation parameter, and transmitting the irradiation plan and the irradiation parameter to a medical linear accelerator; and (5) radiating according to the irradiation plan and the irradiation parameter, observing the breathing condition and narcotism of the experimental dog in the process of radiating, and observing the change of iconography of the radiated lung of the experimental dog. The method of building the radiation pneumonitis model can obtain experimental animals which are stable in a long-term surviving state, and each long-term surviving index of the radiation pneumonitis in an evolutionary process is convenient to observe.

The invention relates to the field of traditional Chinese medicine application and particularly relates to a traditional Chinese medicine for treating radiation pneumonitis. The traditional Chinese medicine is prepared by mixing the following raw materials including radix ophiopogonis, ginseng, pinellia ternata, sesame seeds, loquat leaves, bamboo shavings, bamboo leaves, radix trichosanthis, rhizoma anemarrhenae, bulbus fritilariae cirrhosae, radix adenophorae, polygonatum odoratum, radix stellariae, lily, radix cynanchi atrati, astragalus, tuckahoe, orange peel, atractylodes macrocephala, rhizoma atractylodis, magnolia obavata, fructus akebiae, safflowers, sappan wood, pillworm, nidus vespae, cortex mori, capejasmine, rhizoma anemarrhenae, houttuynia cordata, lonicera japonica, fructus forsythiae, sargentg loryvine stems, semen coicis, Chinese wax gourd semen, fritillaria, trichosanthes kirilowii, platycodon grandiflorum, rhizoma phragmitis, dendrobium, liquorice, caddis, celandine, radix ranunculi ternati and rhizoma arisaematis according to a certain weight ratio. The traditional Chinese medicine is simple in preparation, good in absorption effect, long in medicinal effect lasting time, remarkable in curative effect, free of side effects, high in safety, low in production cost and beneficial to relief of symptoms of patients in time.

An embodiment of the invention provides application of a bone marrow mesenchymal stem cell to prevention of radiation-induced lung injury. The application of the bone marrow mesenchymal stem cell to prevention of the radiation-induced lung injury is the use of the bone marrow mesenchymal stem cell for prevention of radiation pneumonitis and advanced fibrosis and the improvement of the survival rate of the radiation-induced lung injury. Through experiments, the effectiveness of the bone marrow mesenchymal stem cell in preventing radiation-induced lung injury, including radiation pneumonitis andadvanced fibrosis, is verified. The new medical use of the bone marrow mesenchymal stem cell is developed, the bone marrow mesenchymal stem cell is applied to preventing radiation-induced lung injury, including radiation pneumonitis and advanced pulmonary fibrosis, in a groundbreaking way, and a new choice is provided for clinical treatment.

The invention discloses a traditional Chinese medicinal composition for treating radiation pneumonitis. The traditional Chinese medicinal composition for treating radiation pneumonitis is prepared from the following raw materials: codonopsis convolvulacea, abelmoschus sagittifolius, companumoea root, limonium bicolour, Chinese wedelia herb or root, kyllinga monocephala, polytrichum commune, manglietia fordiana fruit, coffee senna and platycodon grandiflorum. The traditional Chinese medicinal composition for treating radiation pneumonitis has the advantages of obvious effect, no side effect and good patient compliance. When decoction of the traditional Chinese medicinal composition for treating radiation pneumonitis is adopted for treating 28 patients for four weeks, 10 patients are healed, effect is taken on 8 patients, effectivity is realized on 7 patients, no effect is taken on 3 patients, and total effective rate is 89.3%.

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating radiation pneumonitis. The traditional Chinese medicine composition comprises, by weight, 5-10 parts of folium mori (bake with honey), 5-10 parts of flos farfarae, 30-40 parts of maltose, 5-15 parts of radix polygonati officinalis, 3-9 parts of liquorice, 3-9 parts of rheum officinale (processing with wine), 5-15 parts of madder (raw), 3-9 parts of thunder god vine, 3-9 parts of corydalis tuber, 3-9 parts of perilla stems, 5-15 parts of semen litchi, 3-9 parts of buckeye, 5-15 parts of acanthopanax and 10-20 parts of hyacinth beans. The traditional Chinese medicine composition for treating the radiation pneumonitis is prepared according to the theory of the traditional Chinese medicines; the traditional Chinese medicines are combined to have the curative effect of treating the radiation pneumonitis; the traditional Chinese medicine composition is a Chinese herbal preparation; the toxic and side effects are small; cost is low; superfine grinding is carried out on the components in the preparation method; and effective compositions of the medicines are released to the maximum degree.

The invention relates to the field of lung cancer treatment, in particular to a kit used for predicting or assisting in prediction for radiation pneumonitis developing after lung radiation. The kit comprises a system for detecting gene types of genetic biomarkers, wherein with the system, whether or not a two or more level of radiation pneumonitis is caused can be evaluated after a cancer in the chest of a patient receives radiation treatment, and thirty-one biomarkers can be used as detection and evaluation target points in total. The kit can accurately and effectively judge whether or not the two or more level of radiation pneumonitis will be caused after the cancer in the chest of the patient receives radiation treatment, is simple and convenient to use, easy to operate and reliable inresult, and has quite important guiding meaning for monitoring and treatment after the patient receives radiation treatment.

The invention discloses a traditional Chinese medicine composition for treating radiation pneumonitis. The traditional Chinese medicine science believes that the external reason of the radiation pneumonitis is radioactive rays which are 'fire heat and pathogenic toxin', the basic pathogenesis is deficient root and excessive superficial, and the impairment of yin, the deficiency of vital energy, the blood stasis and the heat toxicity are key points of the pathogenesis. Traditional Chinese medicines which have the effects of nourishing yin to moisten dryness, clearing away heat and toxic materials, activating blood and expelling phlegm and comprise fine-stemmed dendrobium, discolor ludisia herb, woody-rhizomed fimbristylis herb, trichosanthes root, silene conoidea, viola inconspicua, indigo naturalis, scutellaria indica, geranium wilfordii, underleaf pearl, Indian melothria root and spiral shell are decocted with water and the obtain decoction is taken by patients. The clinical tests prove that the total effective rate of the traditional Chinese medicine composition is 96.7%, and the traditional Chinese medicine composition has a good curative effect and no toxic or side effects.

The invention discloses a traditional Chinese medicine preparation and its preparation and application. The preparation is made from the following raw materials by weight: 20-30 parts of Astragalus root, 20-30 parts of Nansha ginseng, 20-30 parts of Beisha ginseng, and 10-30 parts of Lily Radix. 20 servings, 5-15 servings of dendrobium, 10-20 servings of aster, 10-20 servings of loquat leaves, 10-20 servings of bitter almond, 10-20 servings of Bai Bu, and 10-20 servings of angelica. It has the functions of clearing the lungs, relieving cough and relieving asthma, nourishing qi, nourishing yin and promoting blood circulation. After taking, the drug can directly act on the lesions of radiation pneumonia, inhibit the exudation of inflammatory cells in the alveolar wall, pulmonary interstitial congestion, hemorrhage, edema and alveolar structure damage, reduce the TLR4 signaling pathway signaling molecule protein and local lung. The expression of cytokines in tissue-related cells can reduce the inflammatory response of the lungs and achieve the purpose of delaying or treating radiation pneumonitis.

The invention discloses a traditional Chinese medicine composition for treating radiation pneumonitis. The traditional Chinese medicine composition is prepared from the following raw medicinal materials by weight: 20-30g of Indian buead, 10-20g of fresh ginger, 10-20g of English walnut seed, 10-20g of dried human placenta, 10-20g of platycodon root, 10-20g of ginseng, 10-20g of Chinese angelica, 10-20g of cassia twig, 10-20g of radix notoginseng, 8-15g of Chinese magnoliavine fruit, 8-12g of herb of christina loosestrife, 8-12g of indigowoad leaf, 8-12g of perilla fruit, 8-12g of malaytea scurfpea fruit, 8-12g of turmeric root-tuber, 8-12g of heartleaf houttuynia herb and 3-5g of cicada slough. All the medicinal materials are excellent in compatibility and reasonable in formula to achieve the effects of clearing away heat and toxic materials, removing blood stasis and dispersing lung, resolving carbuncle and expulsing boil, tonifying the lung and invigorating primordial Qi, warming the spleen and stomach to promote transportation of the spleen, regulating the flow of qi to stop coughing and the like, and has unique advantages in the aspects of improving clinical symptoms of radiation pneumonitis patients, improving the quality of life, prolong the survival time and the like.

The present invention includes a method for the use of N-acetylcysteine amide (NACA) or (2R,2R′)-3,3′-disulfanediyl bis(2-acetamidopropanamide) (diNACA) for prevention and treatment of radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), or bronchitis in a human that comprises administering to the human a therapeutically effective amount of NACA or diNACA sufficient to treat, reduce the symptoms, or prevent radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), bronchitis, or respiratory disorder due to oxidative stress, and diNACA for the reduction of mucus viscosity and / or elasticity.

The present invention relates to the field of lung cancer treatment. Specifically, it provides a kit for predicting or assisting in predicting the risk of radiation pneumonitis after lung radiation. A system for detecting the genotypes of genetic biomarkers for grade 2 or above radiation pneumonitis, in which a total of 31 genetic biomarkers can be used as detection and evaluation targets. The kit can accurately and effectively predict whether a patient’s chest tumor will cause radiation pneumonitis of grade 2 or above after receiving radiation therapy. It is easy to use, easy to operate, and the result is reliable. important guiding significance.

The invention discloses a traditional Chinese medicine composition for treating radiation pneumonitis, belonging to the technical field of traditional Chinese medicines. Aiming at the pathogenesis of radiation pneumonitis, the following traditional Chinese medicines with the effects of nourishing yin to moisten dryness, clearing away heat and toxic materials as well as activating blood circulation and resolving phlegm are selected to be prepared into a decoction: wilson begonia rhizome, evergreen mucuna root and leaf, radix asparagi, dendrobium, grassleaf eria herb, ovateleaf coelogyne herb, Japanese platanthera herb, elongated screwtree herb, oroxylum seed, fermented Chinese gall herb and tea leaves, perny holly root, woody hawksbeard root, laxflower embelia root, European white birch bark and thin evodia root. Clinical tests prove that the total effective rate reaches 93.6%.

The invention belongs to the field of disease risk prediction, and relates to a construction and verification method of a novel predictive factor for lung cancer stereotactic radiotherapy radiation pneumonitis risk, which comprises the following steps: A, case collection; b, performing 4DCT simulation positioning scanning; c, sketching a target region and an organ at risk; d, designing a radiotherapy plan; e, extracting tumor related parameters; f, calculating the occurrence probability of the concurrent radiation pneumonitis; g, screening predictive factors; and H, obtaining an intercept point. According to the invention, a novel predictive factor Lung / PTVL which has the highest correlation with RP greater than or equal to 2 in lung cancer SBRT treatment is screened out by using a radioactive biological model for the first time; the intercept point value of the novel predictive factor is obtained for the first time. The novel predictive factor can help clinicians to distinguish patients with high and low RP occurrence risks greater than or equal to 2 levels, and the clinicians can adopt appropriate treatment strategies according to the RP occurrence risks of the patients, so that the RP occurrence probability is reduced, and individualized precise radiotherapy is realized.

The invention discloses an astragalus polysaccharide sustained release microsphere for treating radiation pneumonitis. The astragalus polysaccharide sustained release microsphere comprises the following components in parts by weight: 1 part of astragalus polysaccharide and 3-7 parts of chitosan, wherein the degree of polymerization of chitosan is 30CPS, 50CPS and 130 CPS. The invention simultaneously discloses a preparation method of the astragalus polysaccharide sustained release microsphere. The astragalus polysaccharide sustained release microsphere prepared by virtue of the preparation method has an ideal targeting effect, can slowly release after being administrated, is long in action time and is capable of increasing the concentration of astragalus polysaccharide in target organs, and the high local blood concentration is avoided; the astragalus polysaccharide sustained release microsphere is safe and environmentally friendly and has high treatment effect to radiation pneumonitis and little side effect; the operation is simple and convenient, a process is stable, and industrial production is easily realized; the astragalus polysaccharide sustained release microsphere is high in encapsulation efficiency and drug loading capacity; the skin of a patient is smooth and fine after the administration.

The invention discloses a training method and application of a radiation pneumonia early warning model, and the device comprises a data preprocessing module which is used for dividing a lung CT image into a high lung function region and a low lung function region according to a lung function image; the feature extraction module is used for extracting radiomics and dosiomics from the high-lung function region and the low-lung function region respectively so as to screen out an optimal feature set; and the training module is used for training a radiation pneumonitis early warning model according to the optimal feature set. According to the training method and application of the radiation pneumonia early warning model, the regional difference of high and low functional lungs is fully considered, so that the early warning model obtains a more accurate and robust prediction effect.

The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicine for radiation pneumonitis caused by malignant tumor radiotherapy and a preparation method of the traditional Chinese medicine for radiation pneumonitis caused by malignant tumor radiotherapy. Active ingredients of the traditional Chinese medicine include radix ilicis asprellae, viola acuminata, Chinese forgetmenot root, rhizoma polygonati, herba pholidotae chinensis, selaginella delicatula, perfoliote knotweed herb, northern bedstraw, fiveleaf gynostemma herb, herb of glabrous torenia, root of Chinese eriosema, poria cocos, parochetus communis buch, disporum calcaratum, mulberry fruit, angelica sinensis, picrarrhiza kurroa royle, chlorephytum capense var variegatum hort, radix asparagi, lilies, radix cynanchi, aernaria przewalskii maxim, radix ophiopogonis, radix glycyrrhizae, root of axillaryflower twistedstalk, begonia fimbristipula, tremella and rhizoma menispermi. By symptomatic treatment, the traditional Chinese medicine for radiation pneumonitis caused by malignant tumor radiotherapy has efficacies of Qi tonifying, Yin nourishing, heat clearing, detoxifying, blood circulation promoting, stasis removing, lung moisturizing, cough relieving, sputum reducing, body fluid production promoting, moistening, mind calming and nerve soothing and has the advantages of excellent absorption effects, remarkable curative effects, avoidance of toxic and side effects and clinical adverse reaction and high cure rate of radiation pneumonitis according to clinical verification.

The invention discloses a Chinese medicinal preparation for treating radiation pneumonitis. The radiation pneumonitis belongs to the categories of 'cough' and 'consumptive lung disease' considered by the traditional Chinese medicine, belongs to the evil of toxic heat burns fluid for the irradiation of the radioactive rays and harms the human body vital Qi and Yin blood; and the pathogenesis is heat toxin, Yin deficiency, Qi deficiency, phlegm dampness and blood stasis. Therefore, peristrophe, rhizoma panacis majoris, lignum dalbergiae odoriferae, chicken with yellow feet, adenophora tetraphylla, Ilex cornuta lindl, tricuspid cudrania bark, Chinese pulsatilla root, cacumen biotae, radix tetrastigme, dandelion, gynostemma pentaphyllum, callicarpa bodinieri, argentina anserine, white atractylodes rhizome and licorice are decocted by using water. Clinical experiments in the hospital prove that the total effective rate is 95.3% and the Chinese medicinal preparation is worthy of clinical popularization and application.

Provided is a method for determining whether an individual is likely to be susceptible to radiation pneumonitis from radiation therapy and for developing a treatment based on the determination of susceptibility. The method involves measuring SOD and GPX activity levels. A high SOD or low GPX activity, or a combination thereof, is indicative that the individual is likely to be susceptible to radiation pneumonitis.

The invention provides a traditional Chinese medicine composition for treating radiation pneumonitis. The raw materials of the traditional Chinese medicine composition include Rehmannia glutinosa, Radix Asparagus, Radix Paeoniae Alba, Platycodon grandiflorum, Cordyceps sinensis, Fritillaria sichuanensis, sarcophagus, Eclipta chinensis, Dogwood, loquat leaves, Shouwu vine, scrophulariaceae, honeysuckle, scutellaria baicalensis, licorice, sealwort, American ginseng, three-lens grass, native ginseng, duck celery, golden buckwheat, wintersweet and peacock tail. It not only has the definite effect of anti-radiation pneumonitis, but also can strengthen the whole body and enhance immunity, thus reducing and delaying the recurrence and metastasis of tumors. , significant curative effect, less side effects, and can improve the quality of life of patients, it is worthy of clinical promotion and use.