37results about How to "Prevent macular degeneration" patented technology

An improved lens with Rugate filter specifically designed to be worn in prescription and non-prescription glasses, contact lenses, intraocular lenses and sunglasses, and to provide protection against macular degeneration by reducing harmful visible blue light transmission and ocular photochemical damage. The lens at least includes a single lens layer with a Rugate filter deposited thereon to selectively block visible blue light. Other layers may be added including a polarizing layer, dielectric layer and / or color tint in a lens sandwich configuration, to additionally give a high degree of UVA and UVB protection, color contrast, and glare reduction. The Rugate filter is a stop band which yields an exceptional light transmission profile under all light conditions, thereby maximizing protection as well as clarity of vision. In the multi-layer embodiment, all of the lens layers provide comprehensive protection for preventing macular degeneration, cataracts and other ocular injuries, yet maintain a balanced light transmission profile for visual acuity.

Preparations are disclosed containing the 3R-3'R stereoisomer of zeaxanthin as a sole detectable isomer, packaged for oral ingestion by humans as a therapeutic drug or nutritional supplement. Zeaxanthin is a yellow carotenoid pigment found in the macula (in the center of the human retina), which helps protect retinal cells against phototoxic damage. The pure R-R stereoisomer can be prepared by fermenting cells, such as Flavobacterium multivorum (ATCC 55238), which do not create any detectable quantity of the undesired and potentially toxic S-S or S-R isomers, and which do not synthesize any other carotenoids. The R-R isomer can be concentrated, in large quantities and at low cost, into a viscous oily fluid containing about 5 to 20% zeaxanthin, by means of a simple solvent extraction process. This oily fluid can be mixed with a carrier such as vegetable oil and enclosed within a digestible capsule, comparable to a conventional capsule containing Vitamin E. Alternately, a zeaxanthin fluid can be added to various types of foods, such as margarine, dairy products, syrup, cookie dough, and certain types of meat preparations which are not subjected to harsh cooking. Additional purification steps can also be used to purify zeaxanthin to a granular or powdered state which contains nearly pure zeaxanthin. Such processing can be used to create formulations such as ingestible tablets, and particulate formulations that can be added to soups, salads, drinks, or other foods. Preferred stabilizers and anti-oxidants are also disclosed herein. When consumed by humans in any of these modes, the purified R-R stereoisomer of zeaxanthin can help treat and prevent macular degeneration, one of the leading causes of blindness and vision loss, especially among the elderly.

The invention relates to functional grease composition which is rich in omega-3 unsaturated fatty acid and xanthophyll. The functional grease composition disclosed by the invention can effectively protect eyes from being damaged by light rays, slow down the aging of the eyes, prevent the eyes from generating pathological changes, strengthen the brain and improve the memory.

The invention provides a functional drink with a function of relieving visual fatigue and a preparation method thereof, belonging to the technical field of functional drinks. The functional drink with the function of relieving the visual fatigue is prepared from five raw materials of lutein, medlar, chrysanthemum, white granulated sugar and citric acid, wherein the lutein is extracted from marigold; the functional drink is prepared by adopting a series of steps of pretreating raw materials, extracting, blending and the like. The functional drink prepared by adopting the preparation method is safe and reliable in raw materials; meanwhile, no caffeine, preservative and artificial color are added, and the functional drink has functions of improving the eyesight and relieving the visual fatigue.

A screen protection sheet with a function of blue light filtering comprises a PET film (bi-direction extensible polyester film); an anti-glare layer (or a surface hard-coating layer) on an upper surface of the PET film; an adhesive layer on a lower side of the PET film. A blue light filtering layer is installed on an upper side of the anti-glare layer (or the surface hard-coating layer) or between the film and the adhesive layer, or on an upper side of the anti-glare layer (or the surface hard-coating layer) and a second blue light filtering layer is installed between the film and the adhesive layer. The screen protection sheet may also be formed by a PET film; an anti-glare layer on a lower side of the film; an adhesive layer on a lower side of the anti-glare layer; and a blue light filtering layer on an upper side of the film.

Methods of treating, preventing and / or managing macular degeneration are disclosed. Specific embodiments encompass the administration of a selective cytokine inhibitory drug, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent and / or surgery. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

The invention relates to blueberry and lutein ester bicolor composite tablets and a preparation method thereof, and belongs to the technical field of health-care products. The blueberry and lutein ester bicolor composite tablets comprise the following raw materials in percentage by weight of 40-80% of a glycitols sweetening agent, 3-10% of blueberry powder, 1-5% of black Chinese wolfberry fruit powder, 3-10% of lutein esters, 0.6-2% of zeaxanthin, 1-2.5% of a sour agent, 0-1% of essence and 0.5-8% of a demoulding agent. According to the blueberry and lutein ester bicolor composite tablets provided by the invention, the taste of the lutein esters can be improved, the eating desire and interest are increased, and the blueberry and lutein ester bicolor composite tablets have excellent efficacy of resisting oxidation, improving immunity and the like. Besides, the invention provides the preparation method of the blueberry and lutein ester bicolor composite tablets.

A method of vacuum evaporation coating process that effectively block blue light and infra red light on optical lenses includes five steps. Step one is to provide a lens substrate. Step two is via vacuum evaporation coating process to evaporate silicon dioxide layer on the surface of said lens substrate. Step three is to use the vacuum evaporation coating process to evaporate zirconium dioxide layer on top of the silicon dioxide layer. Step four is to repeat step two and three to coat a plurality of silicon dioxide layers and zirconium dioxide layers. Step five is to repeat step two thus forming a multilayer stacking structure. Therefore, said stacking structure can block partial blue light and infrared light on optical lenses to achieve the effect of eye protection.

The invention relates to a blue-light-resistant resin lens of 1.60 in refractivity. The blue-light-resistant resin lens comprises a resin substrate of 1.60 in refractivity, a hardened film layer is dipcoated on the resin substrate, and a first SiO2 film layer, a ZrO2 film layer, a second SiO2 film layer, a Ti2O3 film layer, an In2O3 film layer and a third SiO2 film layer are sequentially deposited on the surface of the hardened film layer. The blue-light-resistant resin lens can filter 40-50% of blue light of 400-500nm in wavelength and can effectively filter blue light radiation, pricking and soreness of eyes can be reduced, eye dryness and eye fatigue can be reduced, and cataract and maculopathy can be prevented.

The invention relates to an anti-blue-ray resin lens with the refraction index of 1.56. The anti-blue-ray resin lens with the refraction index of 1.56 comprises a resin substrate with the refraction index of 1.56; the resin substrate is dip-coated with a hardened film; a first SiO2 film, a ZrO2 film, a second SiO2 film, a Ti2O3 film, an In2O3 film and a third SiO2 film are deposited on the surface of the hardened film in sequence. According to the resin lens disclosed by the invention, the effect of filtering blue rays with the wavelength of 400 to 500 nm can reach 40 to 50 percent; blue ray radiation can be filtered effectively; sharp pain, soreness and swelling of eyes can be reduced; eye dryness and eye fatigue can be reduced; cataract and macular degeneration can be prevented.

The present invention relates to the compositions and methods for treating or alleviating conditions that affect the epidermis (e.g., wrinkles, sun damaged skin, symptoms of aged skin, or the like).

The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.

The invention provides a cereal rice production system and a production process thereof. The cereal rice production system mainly comprises a proportioning machine, a twin-screw extrusion cutting forming machine, a vibrating screening machine, a microwave drying system, a drum type cooling device and a vacuum packaging machine sequentially. A cereal rice production process comprises proportioning, extrusion forming and granulating, screening, drying, cooling and packaging. The cereal rice produced by using the cereal rice production equipment and the production process is balanced in nutritional proportion, wherein components such as corn, sorghum, tartary buckwheat and the like are coarse food grain which is less in sugar content and facilitates human health. The cereal rice is particularly suitable for crowds inappropriate to intake excessive sugar such as diabetics and the like to eat. The cereal rice finished product is uniform in granularity and relatively attractive, the water content is controlled with 11-12%, so that the cereal rice is properly stored and is hard to mildew. The production process provided by the invention is short in process, the production system is simple in equipment structure, energy-saving and environmental-friendly, and the production cost is lowered.

The present invention provides a pharmaceutical composition for removing drusen, suppressing formation of drusen, and / or treating and / or preventing age-related macular degeneration comprising the compound of formula (I) wherein Ra is independently selected from the group consisting of halo, hydroxy, alkyl, halo-substituted alkyl, aryl, halo- or alkyl-substituted aryl, alkoxy, hydroxy- or carboxy-substituted alkoxy, aryloxy, halo- or alkyl-substituted aryloxy, CHO, C(O)-alkyl, C(O)-aryl, C(O)-alkyl-carboxyl, C(O)-alkylene-carboxy ester and cyano, and m is an integer selected from 0 to 4.

The invention discloses a preparation method for nutrient five-cereal coarse food. The nutrient five-cereal coarse food is prepared by the following raw materials in parts by mass: 5-15 parts of rice,5-15 parts of wheat, 5-15 parts of beans, 5-15 parts of corn, 5-15 parts of potatoes, 5-20 parts of sesame, 0.5-1 part of a spice agent, 1-2 parts of a flavoring agent, 40-60 parts of water, and 1-5parts of salad oil. The nutrient five-cereal coarse food is capable of, through adding the rice, the wheat, the beans, the corn, the potatoes and the sesame, supplementing nutrients to many symptoms well, has the prevention and treatment effect, and has a great promotion value.

The invention discloses a contact lens material. The contact lens material is prepared from the following raw materials: hydroxyethyl methacrylate, 2-methacryloyloxyethyl phosphorylcholine, azophenylmethacrylate, ethylene glycol dimethacrylate, 3-methacryloxypropyltrimethoxysilane, 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate, azodiisobutyronitrile, methacrylic acid and sodium hyaluronate. The preparation method of the contact lenses specifically comprises the following steps: (1) weighing raw materials; (2) respectively manufacturing a male die and a female die; (3) conducting pattern printing; (4) conducting blank forming; (5) conducting demoulding; and (6) conducting stripping to obtain a product. The contact lens material provided by the invention has the advantages of good hydrophilicity, high water content and good biocompatibility, so that the prepared contact lens has good oxygen permeability and water content, is comfortable to wear, also has ultraviolet protection and purplelight and blue light filtering functions, and better cares eyes.

The invention discloses an emulsion with stable liposome and a preparation method thereof, and relates to the field of food processing. The preparation method of the emulsion with stable liposome comprises the following steps: preparing a liposome film, preparing a dispersion liquid, preparing a crude emulsion and preparing the emulsion with stable liposome. By reasonably proportioning the components of the liposome and optimizing the preparation steps and parameters, the loading rate of vitamin E, vitamin B2 and beta-carotene is improved, and meanwhile, the thermodynamic stability of the emulsion with stable liposome is also improved, so that the emulsion can be kept stable during ultrahigh-temperature instantaneous sterilization, the vitamin B2, vitamin E and beta-carotene are delivered in target, digestion and absorption are promoted, the effect of preventing maculopathy is achieved, and meanwhile the beneficial health-care function is achieved.

The present invention discloses one kind of health flour of various kinds of grains and its production process. The health flour is produced with coix seed, corn and buckwheat in certain weight proportion. It may be produced into food with special flavor, high nourishing health care function, good taste and high marketability.

The invention discloses nutrient-enriched natural astacin containing quail feed. The quail feed contains, by mass, 1-10% of natural astacin and 90-99% of poultry feed. Natural astacin is extracted from algae, fungi, fish, shrimps, crabs and plants. According to the quail feed, the biological and pharmaceutical characteristics of astacin are utilized, peculiar super-strong tinting strength and a nutritious health-care function are brought into play, natural astacin is adopted and is transferred and stored in quail egg yolk by aid of the effective conversion ability of quails, and therefore a nutrient-enriched and health-care functional product easy to accept by the mass is produced. Astacin in obtained quail eggs rich in natural astacin is mainly concentrated in quail egg yolk; the quail eggs can serve as common food or health-care food with a special function or main materials or auxiliary materials or the like of other food.

The present invention includes a method for the use of N-acetylcysteine amide (NACA) or (2R,2R′)-3,3′-disulfanediyl bis(2-acetamidopropanamide) (diNACA) for prevention and treatment of radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), or bronchitis in a human that comprises administering to the human a therapeutically effective amount of NACA or diNACA sufficient to treat, reduce the symptoms, or prevent radiation pneumonitis and treatment of pulmonary function in Cystic Fibrosis (CF), chronic obstructive pulmonary disease (COPD), bronchitis, or respiratory disorder due to oxidative stress, and diNACA for the reduction of mucus viscosity and / or elasticity.

The invention discloses a nutrition fortified cattle feed containing natural astaxanthin. The nutrition fortified cattle feed is prepared from the following components in percentage by weight: 1-10% of natural astaxanthin and 90-99% of a compound feed, wherein the natural astaxanthin is extracted from algae, funguses, fish, shrimps, crabs, plants and the like. The biologic characteristics and the pharmacal characteristics of the astaxanthin are utilized, and specific super-strong tinting strength and nutritive health-care functions are exerted; based on the compound feed for cattle, the natural astaxanthin is added, the absorption, the conversion and the storage of the cattle are effectively utilized, the natural astaxanthin in the feed can promote microorganisms and body tissue in cattle rumens to be synthesized into various vitamins, the appetite is stimulated, reproduction and lactation are facilitated, the healthy state of a respiratory system and mucosae is maintained, and normal eyesight is maintained; and the natural astaxanthin which is not converted finally is transferred and stored into the muscle cells of the cattle, the generation of allochromatic metmyoglobin cells is avoided, and the generation of oxidation reactions in muscle cells of beef is thoroughly avoided.

The invention relates to a lutein soft capsule and a preparation method thereof. The lutein soft capsule is composed of a capsule skin and a capsule content, wherein the capsule content is made of the following raw materials in parts by weight: bilberry extract 110 ~130, lutein 12~20, taurine 45~60, natural β-carotene 7~11, phospholipids 2~2.4, beeswax 24~29 and linseed oil 200~250; the capsule skin consists of the following weight 130~170 parts of raw materials: gelatin 130~170, glycerin 62~72, purified water 110~130, brilliant blue 0.029~0.032, allura red 0.0275~0.0295, caramel color 0.1428~0.1628 and titanium dioxide 0.2192~0.2392. The invention has beneficial effects: reasonable compatibility, effective relief of asthenopia, improvement of blurred vision, dry eyes, eye swelling, eye pain, photophobia and other symptoms of patients.

The present invention discloses a composite nutrient noodles, it is characterized by that in the dough for making noodles the food grain flour other than wheat flour and rice flour can be added, and in the flavouring material several vitamin powders and trace element powders are added, so that said noodles not only can provide 6 nutrients-water, protein, fat, carbohydrate, mineral matter and vitamin necessary for human body, but also can supplement other nutrient components, such as vitamin A, D, B1, B2, folic acid, nicotinic acid and calcium, iron and zinc, etc.

The invention relates to eye drops prepared by using a liposome technology, in particular to a formula of zeaxanthine dipalmitate liposome eye drops and a preparation method thereof. The zeaxanthine dipalmitate liposome eye drops are prepared from the following raw materials in percentage by mass: 78.00 to 94.00 percent of water for injection, 5.00 to 25.00 percent of zeaxanthine dipalmitate liposome, 0.05 to 0.30 percent of sodium hyaluronate, 0.05 to 0.15 percent of panthenol, 0.05 to 0.10 percent of boric acid, 0.01 to 0.05 percent of vitamin B12, 0.01 to 0.05 percent of vitamin B6, 0.01 to 0.05 percent of glycerol, 0.50 to 0.70 percent of sodium chloride and 0.10 to 0.30 percent of phenoxyethanol. The eye drops are relatively simple in formula, good in stability and non-irritant to human eyes, zeaxanthin dipalmitate is entrapped by lipidosome, the problems of poor water solubility and low bioavailability are fundamentally solved, the eye drops can enter corneal cells more easily, leakage is reduced, meanwhile, the stability is improved. The efficient delivery of the zeaxanthine dipalmitate is fully realized, and the effect of improving eyesight is achieved.