A high-concentration salty wastewater MVR (mechanical vapor recompression) evaporative crystallization treatment system comprises a raw material storage tank, a feed pump, a plate heat exchanger, a DTB evaporation crystallizer heating chamber, a DTB evaporation crystallizer, a vacuum evaporation crystallizer heating chamber, a vacuum evaporation crystallizer, a first hydraulic cyclone, a sodium sulfate slurry barrel, a double-stage pusher centrifuge, a vibration fluidized-bed dryer, a first mother liquor storage tank, a first mother liquor pump and a mother liquor circulating pump. The high-concentration salty wastewater MVR evaporative crystallization treatment system is characterized in that the raw material storage tank is sequentially connected with the feed pump, the plate heat exchanger, the DTB evaporation crystallizer heating chamber, the DTB evaporation crystallizer and the vacuum evaporation crystallizer heating chamber. The system is low in comprehensive energy consumption, finally obtained anhydrous sodium sulfate quality meets the requirements of GB / T6009-2014 industrial anhydrous sodium sulfate class-II top quality goods, sodium sulfate content is higher than or equal to 98%, and industrial sodium sulfate meets solarized sodium sulfate secondary standard requirements of national industrial sodium sulfate standards (GBT5462-2003).