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40 results about "Pharmaceutical sciences" patented technology
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The pharmaceutical sciences are a group of interdisciplinary areas of study concerned with the design, action, delivery, disposition, inorganic, physical, biochemical and analytical biology, epidemiology, statistics, chemometrics, mathematics, physics, and chemical engineering, and applies their principles to the study of drugs. The pharmaceutical sciences are further subdivided into several specific specialties, with four main branches: Pharmacology: the study of the biochemical and physiological effects of drugs on human beings. Pharmacodynamics: the study of the cellular and molecular interactions of drugs with their receptors. Simply "What the drug does to the body" Pharmacokinetics: the study of the factors that control the concentration of drug at various sites in the body. Simply "What the body does to the drug" Pharmaceutical toxicology: the study of the harmful or toxic effects of drugs. Pharmacogenomics: the study of the inheritance of characteristic patterns of interaction between drugs and organisms. Pharmaceutical chemistry: the study of drug design to optimize pharmacokinetics and pharmacodynamics, and synthesis of new drug molecules.
Hospital medication management system with medication safety monitoring and intervening functions
The invention relates to a hospital medication management system with the medication safety monitoring and intervening functions. The hospital medication management system with the medication safety monitoring and intervening functions is composed of a medication safety monitoring system and an early informatization intervening system. The computer database technology and other technologies are adopted for the medication safety monitoring system. According to the professional examination principle in the medicine science and the pharmaceutical science, with the specialized knowledge in the medicine science and the pharmaceutical science as standards, relevant medicine data information can be provided when doctor's advice is entered and examination of drug allergy histories, drug interactions, contraindications, side effects, external injection medicine compatibility and the like is performed on the doctor's advice to assist a doctor in correctly screening medicines and determining the doctor's advice, a prompt and an alarm can be given timely when problems are found, and thus the possibility of errors is reduced.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
Coupling medicament for treating diabetes mellitus and medicinal application thereof
InactiveCN102107006AFast and strongSmall side effectsMetabolism disorderBlood disorderChemical structureMedicinal herbs
The invention discloses a natural coupling medicament for treating diabetes mellitus and other blood vascular diseases. The medicament has a chemical structure with a general formula (I), and is formed by coupling natural ingredients of active Chinese medicinal herbs and a nitric oxide donor. The coupling medicament can be used for preparing finished product medicaments for treating the diabetes mellitus, and has the effects of reducing blood sugar, blood pressure and blood fat, resisting platelet aggregation, resisting atherosclerosis and the like. After entering human bodies, the coupling medicament can be subjected to enzymolysis in vivo to release nitric oxide and natural medicinal ingredients, so the natural coupling medicament has the advantages of small toxic and side effect and lasting effect of natural medicaments and has the characteristic of quick and high activity of the nitric oxide, and has the wide application range in pharmaceutical science.
Owner:CHIFCON DRUG DISCOVERY SUZHOU
2-aminothiazoles compound
The invention relates to the technical field of medicinal chemistry, in particular to a 2-aminothiazoles compound or acceptable slat in pharmaceutical science, a preparing method thereof, pharmaceutical composition comprising the same, and application thereof in antineoplastic drug preparation.
Owner:CHIA TAI TIANQING PHARMA GRP CO LTD
Medicine compounds for treating diabetic nephropathy
ActiveCN101229373AGood curative effectImprove rational drug useOrganic active ingredientsMetabolism disorderRational useTreatment effect
The invention provides a novel medical composite for treating diabetic and nephropathy, which comprises insulin sensitizer and endothelin receptor blocker. The invention scientifically combines two medicines with complete different mechanisms of action, and reaches the target of mechanism complementation, mutual coordination, enhancing treatment effect and rational use of drug. The invention not only has good coordination in reducing blood sugar, but also achieves quite good coordination effect for protecting kidney. The invention is probably a new breakthrough of the treatment method of diabetic nephropathy.
Owner:LUNAN PHARMA GROUP CORPORATION
Method for producing fullerene suspension
InactiveUS20080217445A1Improve dispersion stabilityIncrease peak outputMaterial nanotechnologyFullerenesDispersion stabilityNanoparticle
The present invention provides a fullerene suspension and a method for producing a fullerene suspension having high dispersion stability without any chemical compound. Also, the fullerene suspension and its producing method makes it possible to be applied in various fields including the field of medical and pharmaceutical science and the field of foods and environment, in which the fullerene suspension obtained by the prior methods had not been applied. The fullerene is ground to form nanoparticles by irradiating a fullerene in a poor solvent with a laser. The pulse laser having a width of several-ten femtoseconds to several-hundred nanoseconds is appropriately applied.
Owner:ABSIZE INC
Method for formulating large diameter synthetic membrane vesicles
The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
Owner:PACIRA PHARMA INC
Doxycycline hydrochloride dual-release preparation and preparation method thereof
ActiveCN102579408AImprove stabilityImprove bioavailabilityAntibacterial agentsTetracycline active ingredientsFormularyImmediate release
The invention belongs to the field of pharmaceutical science, and particularly relates to a doxycycline hydrochloride dual-release preparation and a preparation method thereof. The preparation consists of micropills with different release performance, namely the preparation is formed by mixing 50 to 85 weight percent of quick-release micropill and 50 to 15 weight percent of sustained-release micropill. The preparation method comprises the following steps of: preparing micropill cores according to a formula, and preparing the quick-release micropills by using the micropill cores; preparing thesustained-release micropills by using the quick-release micropills; and filling the quick-release micropills and the sustained-release micropills into capsules in a ratio to obtain doxycycline hydrochloride dual-release capsules. Pharmacokinetic experiments in the dual-release capsule bodies indicate that medicines in the doxycycline hydrochloride dual-release capsules can be released twice when the doxycycline hydrochloride dual-release capsules are taken once every day, and the concentration of two-time peaks is close; the concentration peak of medicines in blood plasma is reduced by a dual-release model, the possibility of side effect is reduced, and the compliance of the administration of patients is improved; and due to the adoption of a new formula and a new process, the difference among batches is reduced, and the stability of samples is improved, so the doxycycline hydrochloride dual-release preparation is suitable for industrial production.
Owner:ZHONGSHUAI PHARMA SCI & TECH CO LTD
Synergistic antifungal compositions and methods thereof
The present invention relates to the field of antimicrobials and pharmaceutical sciences. The invention provides antifungal compositions for the management of fungal growth and treatment of fungal infections, including treatment of resistant fungal infections. The present compositions comprise at least one antifungal agent and at least one medium-chain saturated or unsaturated fatty acid having carbon chain length of C-1 to C-14 or ester thereof, optionally along with excipient(s), giving rise to a synergistic antifungal activity.
Owner:VYOME THERAPEUTICS LTD
Metronidazole derivative and preparing method and application thereof
ActiveCN104926792ABroad-spectrum anti-cancerBroad-spectrum antitumor activityOrganic active ingredientsOrganic chemistryDiseaseSolvent
The invention relates to a metronidazole derivative shown in the formula (1) (please see the specific formula in the specification) and salt or solvate which can be accept by the metronidazole derivative on the pharmaceutical science. R can be the same or different and can be independently selected from hydrogen, halogen, a cyano group, nitro, C1-C6 alkyl, C1-C6 alkoxy, halogenation C1-C6 alkyl, halogenation C1-C6 alkoxy, aryl, aryloxy and the like, and n is an integer from 0 to 4. The invention further relates to a preparing method and application of the metronidazole derivative in the formula (I). The compound or the salt of the compound has the strong inhibitory activity on the colorectal cancer cell strain HCT-116, the human lung cancer cell strain A549 and the breast cancer cell strain MCF-7. The compound has broad spectrum on anti-cancer activity and can serve as candidate medicine or a lead compound for treating tumors, cancers and other diseases.
Owner:XIAMEN INST OF RARE EARTH MATERIALS
Chinese medicinal composition for treating gastropathy and preparation method thereof
ActiveCN101708306AGood treatment effectGood effectDigestive systemMammal material medical ingredientsTreatment effectAdemetionine
The invention provides a Chinese medicinal composition for treating gastropathy and a preparation method thereof. The composition is prepared from golden thread, Chinese sage herb, costustoot, medcinal evodia fruit, largehead atractylodes rhizome, poria, villous amomum fruit, chicken's gizzard-membrane, malt, rice-grain sprout, medicated leaven, hawthorn fruit, radish seed and yanhusuo. The Chinese medicinal composition for treating the gastropathy of the invention is a pure Chinese medicinal preparation. Based on the therapeutic principle of Chinese traditional medicine and the modern pharmaceutical science, the curative effect of the product is improved by separating and purifying the active components in the Chinese medicament. And the Chinese medicinal composition is used for treating the gastropathy with the symptoms of sallow complexion, hypodynamia, loose stools, poor appetite, gastrectasia, stomach ache, belching, hot drink preference, pressure-relieved gastral cavity, whitish tongue, thin and whitish fur, weak and fine pulse and the like caused by spleen deficiency and stomach cold, and has obvious efficacy.
Owner:蚌埠丰原涂山制药有限公司
Potassium sodium dehydroandrographolide succinate enteric-coated preparation and preparation method
ActiveCN107982241AImprove Medication AdherenceReduce allergic reactionsOrganic active ingredientsAntiviralsSide effectActive component
The invention belongs to the field of medicine processing, and particularly relates to a potassium sodium dehydroandrographolide succinate enteric-coated preparation and a preparation method. The preparation method comprises the specific steps of forming a specific formula based on the effective component potassium sodium dehydroandrographolide succinate and auxiliary materials acceptable in pharmaceutical science, coating an isolation layer and coating an enteric-coated layer through a specific processing technology, then adding suitable auxiliary materials so as to prepare an enteric-coatedcapsule, enteric-coated particles and enteric-coated dry suspension. The refinement method for potassium sodium dehydroandrographolide succinate greatly reduces impurities and lowers occurrence rate of side effects; the special preparation process and parameter for producing the potassium sodium dehydroandrographolide succinate enteric-coated preparation can effectively protect active components of potassium sodium dehydroandrographolide succinate, thereby guaranteeing the medicine effect of the finished product and improving the bioavailability of oral potassium sodium dehydroandrographolidesuccinate. The preparation method has easy steps, is easy to operate and is suitable for industrial production.
Owner:HUANGSHAN C KING PHARMA
Method for producing fullerene suspension
InactiveUS7900855B2Improve dispersion stabilityHigh outputMaterial nanotechnologyFullerenesDispersion stabilityNanosecond
The present invention provides a fullerene suspension and a method for producing a fullerene suspension having high dispersion stability without any chemical compound. Also, the fullerene suspension and its producing method makes it possible to be applied in various fields including the field of medical and pharmaceutical science and the field of foods and environment, in which the fullerene suspension obtained by the prior methods had not been applied. The fullerene is ground to form nanoparticles by irradiating a fullerene in a poor solvent with a laser. The pulse laser having a width of several-ten femtoseconds to several-hundred nanoseconds is appropriately applied.
Owner:ABSIZE INC
Guaiac orchid hydrocarbon azulene ramification and preparing method and application thereof
InactiveCN104003959AHas anti-peptic ulcer activityExcellent B2Organic active ingredientsOrganic chemistryPeptic ulcerPharmaceutical sciences
The invention provides guaiac orchid hydrocarbon azulene ramification shown in the formula I in the specification or a salt or pro-drug accepted in the pharmaceutical science. R represents C1-C4 alkyl group, phenyl group or substituent phenyl group. The substituent group of the substituent phenyl group is selected from C1-C4 alkyl group, halogen or C1-C4 alkoxy. As shown in the research, the compound has a certain anti-peptic ulcer activity, the activity of the compound B2 and B8 is superior, the anti-gastric ulcer function of the compound B2 and B8 is equal to or close to that of the typical medicine of omeprazole, and a new choice is provided for clinical medication.
Owner:SICHUAN UNIV
Application of N-acetylcysteine in preparation of drugs for preventing and treating DNA damage and tissue damage induced by synchrotron radiation
The invention relates to an application of an antioxidant drug in the pharmaceutical science field, and especially relates to an application of N-acetylcysteine in preparation of drugs for preventing and treating gonads and other tissue DNA damage and tissue damage induced by synchrotron radiation X-rays. According to experimental results, N-acetylcysteine is indicated to be capable of protecting the double-strand DNA damage caused by synchrotron radiation X-ray radiation, and protecting testicular seminiferous tubule cell layer number reduction caused by the synchrotron radiation X-ray radiation; and the antioxidant is indicated to have important application value in the preparation of the drugs for preventing and treating the synchrotron radiation damage.
Owner:SHANGHAI JIAO TONG UNIV
Compound antihypertensive preparation and application of compound antihypertensive preparation
InactiveCN104324377AReasonable compositionGood synergyOrganic active ingredientsCardiovascular disorderPharmaceutical medicinePharmaceutical Aids
The invention provides a medicine composition for treating hypertension. The medicine composition is characterized in that the medicine composition comprises (1) angiotensin II receptor antagonists, (2) diuretic metolazone and (3) acceptable auxiliary materials on pharmaceutical science. The weight proportion of the angiotensin II receptor antagonists to the metolazone is 20-200:0.5-10; the angiotensin II receptor antagonists and the metolazone are combined to strengthen the collaboration antihypertensive effect; untoward effects are reduced; the compliance of patients is improved; the medication crowds are wide; and the medicine composition can be used by the patients with the seriously-damaged renal function. The medicine composition is suitable for treating mild and moderate primary hypertension, and is particularly suitable for treating secondary hypertension caused by kidney damage.
Owner:XIAN LIBANG ZHAOXIN BIOTECH CO LTD
Dihydroartemisinin modified drug delivery carrier and application thereof in pharmaceutical science
ActiveCN108498485AImprove stabilityGood internal circulationOrganic active ingredientsPharmaceutical non-active ingredientsPolyethylene glycolPharmaceutical formulation
The invention belongs to the field of new auxiliary materials and new dosage forms for pharmaceutical preparations and relates to design and application of a drug delivery system taking endogenous apolipoprotein E as a target spot, comprising design and synthesis of a carrier structure modifying a hydrophobic material by virtue of a polyethylene glycol (PEG) connecting arm by dihydroartemisinin (DHA). The used carrier material actively customizing apolipoprotein E takes DHA as a target head, PEG as a connecting arm and the hydrophobic material (such as PLGA) as an anchoring part. A nano delivery preparation prepared from the carrier material can encapsulate multiple anti-tumor drugs, and by virtue of interaction of the apolipoprotein combined with DHA on the surface of the nano delivery preparation and low density lipoprotein receptors (LDLr) highly expressed by tumor cells, multiple biological transmission barriers are overcome, and accumulation of nano particles at tumor parts as well as intake and anti-tumor activity in the tumor cells are effectively improved. The nano delivery preparation has good stability, high safety and excellent targeting capability, can be applied to intravenous injection and has a relatively great market application prospect.
Owner:SHENYANG PHARMA UNIVERSITY
Traditional Chinese medicine preparation for treating stroke and preparation method thereof
InactiveCN103830482AAlleviate damage symptomsGet rid of sicknessNervous disorderAnthropod material medical ingredientsDiseaseMedicinal herbs
The invention discloses a traditional Chinese medicine preparation for treating stroke and a preparation method of the preparation, which belong to the field of traditional Chinese medicines. The traditional Chinese medicine preparation is prepared from the following raw materials as effective components: aconitum kusnezoffii, alhagi sparsifolia sugar grain, cynanchum thesioides, chufa, roughhaired holly root, calcined oyster shell, mahonia bealei carr, arrowhead, hawksbill, clematis filamentosa, herb of shiny cinquefoil, michelia figo, cassia sophera, cortex albiziae, basil and cannabis sativa. The traditional Chinese medicine preparation disclosed by the invention is reasonable in matching of selected medicine materials, meets the pharmaceutical science of traditional Chinese medicines and theories of modern medicine and pharmacology, has the functions of calming the nerve, inducing resuscitation, dispelling melancholy, restoring consciousness, dispelling wind, smoothening qi, calming down the heart and removing carbuncle, has a remarkable curative effect on symptoms of hemiplegia, facial paralysis, unconsciousness remaining, disordered consciousness, delirious speech, madness and the like caused by stroke, is short in treatment course, rapid to take the effect and free of toxic or side effect, can alleviate the symptom of nervous centralis cell damage caused by cerebral ischemia of a patient, can relieve the patient with stroke from illness, is safe, reliable and low in cost, and is worthy of clinical popularization and application since the disease does not relapse after being healed.
Owner:孙逊
Nucleus structural model
InactiveCN104392649AEasy to understandHelp with teaching activitiesEducational modelsPharmaceutical sciencesProton
The invention discloses a nucleus structural model, and relates to the technical field of nucleuses. The nucleus structural model comprises a main structure and an auxiliary structure, wherein the main structure adopts a 1-3-axis 1-7-layer gyro structure, sequentially comprising a helium axis, 8 pairs of single-stranded protons as a second layer, 8-18 pairs of protons as third, fourth, fifth and sixth layers, and supporting protons as an outmost layer; the nucleus structure model adopts a principle as follows: the second layer formed by 8 pairs of the single-stranded protons has a first determinant factor as follows: arrangement of the 8 pairs of the single-stranded protons is adapted to gyro needs and magnetic needs and the 8 pairs of the single-stranded protons are tightly arranged. The nucleus structural model helps people to understand the nature, benefits physical, chemical and mechanical researches, facilitates the development of materials, is conducive to the development of biochemical, biological, medical and pharmaceutical sciences and other related disciplines, is helpful to teaching activities, and can be a model for developing the intelligence of children.
Owner:叶恒俊
A kind of 2-aminothiazole compound
The invention relates to the technical field of medicinal chemistry, in particular to a 2-aminothiazoles compound or acceptable slat in pharmaceutical science, a preparing method thereof, pharmaceutical composition comprising the same, and application thereof in antineoplastic drug preparation.
Owner:CHIA TAI TIANQING PHARMA GRP CO LTD
Ciona intestinalis polypeptide and preparation method thereof
ActiveCN102174096ANovel structureHigh activityPeptide preparation methodsAntineoplastic agentsHplc methodFiltration
The invention belongs to the filed of pharmaceutical sciences and particularly relates to ciona intestinalis polypeptide and a preparation method thereof. The ciona intestinalis polypeptide has the N- terminal sequence of YQPDKFMLRGELRNN, the molecular weight of 5931Da and the isoelectric point of 7.25. The preparation method of the ciona intestinalis polypeptide comprises the following steps: precipitating fresh ciona intestinalis by using 10-90% acetone, dialyzing and desalting active components, and purifying by adopting ion-exchange chromatography, gel filtration chromatography and HPLC (high-performance liquid chromatography) to obtain the ciona intestinalis polypeptide which has the molecular weight of 5931Da. The in vivo and in vitro activity experiments verify and confirm that theapplication of the ciona intestinalis polypeptide to malignant tumor prevention and treatment.
Owner:INST OF OCEANOLOGY - CHINESE ACAD OF SCI
DNA (deoxyribonucleic acid) phosphorothioation modifier gene cluster
ActiveCN105087554AImprove dynamicsFermentationVector-based foreign material introductionHeterologousPhosphoric acid
The invention discloses a DNA (deoxyribonucleic acid) phosphorothioation modifier gene cluster. DNA phosphorothioation modifiers controlled by the gene cluster are single-chain modifiers, selective sequence sites are CpsC, the integral phosphorothioation modifier gene cluster comprises four genes including an encoding cysteine desulfurase gene and a 3' phosphoadenosine-5' phosphosulfate (PAPS) reductase gene, and encoding proteins of the two other genes are members of ABC transport protein families and DUF4007 super-families respectively. The DNA phosphorothioation modifier gene cluster has the advantages that the genes and the proteins of the genes can be used in the bio-pharmaceutical science fields of heterogeneous-source host DNA modification, epigenetics, cell-free phosphorothioation modification system construction, oligonucleotide medicine modification and the like.
Owner:WUHAN UNIV
Intelligent medicine box
PendingCN114366668ASimple and fast operationCreative toolDrug and medicationsParticular environment based servicesOnline doctorMedication monitoring
The intelligent medicine box comprises a box body, an induction display module, a communication module and a power module are installed in the box body, the communication module is connected with an online query module, the online query module is connected with a data analysis and mining module, and the data analysis and mining module is connected with a directional pushing module. The directional pushing module is connected with a data storage module, the data storage module is connected with a data acquisition module, the data acquisition module is connected with a data reading module, the data reading module is connected with a medication monitoring module, and the online query module comprises an online doctor and a medication consultation unit. The system is easy and convenient to operate, remote monitoring can be achieved through a mobile phone, a medicine scientific management system and an end-to-end BLE technology platform are combined, the personal medicine management system which is safe and effective and has creativity and expansibility is built, data of personal medicine taking habits are accurately collected, and analysis of the personal and medical systems is facilitated.
Owner:上海仪电溯源科技有限公司
Palladium coordination compound for antitumor drugs
InactiveCN101863927ASignificantly effective in treating tumorsGood effectGroup 8/9/10/18 element organic compoundsAntineoplastic agentsArylAliphatic hydrocarbon
The invention belongs to the field of pharmaceutical science, and relates to a palladium coordination compound for antitumor drugs. The structural formula of the palladium coordination compound is shown in the specification, wherein a substituent group N-N is independently selected from aliphatic diamine or substituted aliphatic diamine, aromatic diamine and various substituted aromatic diamine; and an R1 or R2 is independently selected from substituted or unsubstituted branched chains and linear chain or cyclic annular aliphatic hydrocarbon, aryl groups, and nonaromatic or aromatic heterocycle groups.
Owner:HEBEI UNIVERSITY
Anti-hepatic fibrosis traditional Chinese medicine compound composition and application thereof
InactiveCN112755084AHas anti-hepatic fibrosis effectAvoid bleedingDigestive systemPlant ingredientsAngelica Sinensis RootAcute hepatic failure
The invention discloses an anti-hepatic fibrosis traditional Chinese medicine compound composition and application thereof The traditional Chinese medicine compound composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of astragalus membranaceus, 10-30 parts of radix pseudostellariae, 5-15 parts of angelica sinensis, 5-15 parts of glossy privet fruit, 5-15 parts of poria cocos, 10-30 parts of roasted rhizoma atractylodis macrocephalae, 5-15 parts of pericarpium citri reticulatae, 5-15 parts of wine-processed scutellaria baicalensis and 3-10 parts of honey-fried licorice root. According to the pathogenesis of hepatic fibrosis, a syndrome differentiation and treatment method is adopted, a prescription is screened in combination with pharmacological experiments, and after the medicines in the prescription are scientifically compatible, the traditional Chinese medicine composition has a good liver protection effect on chronic and acute hepatic failure patients clinically, has a good prevention and treatment effect on hepatic fibrosis in vivo, inhibits proliferation of activated hepatic stellate cells in vitro, has the efficacy of preventing liver cell injury, has a good anti-hepatic fibrosis effect, is a promising traditional Chinese medicine compound, and has a good market promotion value.
Owner:NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Medicine composition for treating malaria
ActiveCN108078989AImprove living conditionsImprove symptoms of nerve damageOrganic active ingredientsNervous disorderCurative effectPharmaceutical drug
The invention belongs to the field of pharmaceutical science, and relates to a traditional Chinese medicine composition, in particular to a medicine composition for treating malaria. The medicine composition disclosed by the invention has the characteristics of good curative effect, quick effect, stable quality and capability of relieving nerve injury symptoms. The medicine composition disclosed by the invention is prepared from artesunate and ligustrazine or medicinal salt thereof, and the weight ratio of which is (1 to 10):(10 to 1).
Owner:INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
Traditional Chinese medicine capsule for preventing or treating ED (erectile dysfunction) of middle-aged and elderly men
ActiveCN103432313AImprove the level ofEnhanced target organ effectsCapsule deliverySexual disorderMonkshoodsPharmaceutical sciences
The invention discloses a traditional Chinese medicine capsule for preventing or treating ED (erectile dysfunction) of middle-aged and elderly men. The capsule comprises active ingredients and auxiliary materials acceptable in pharmaceutical science, wherein the active ingredients are prepared through water extract and alcohol precipitate by the following traditional Chinese medicinal mater in parts by weight: 12-18 parts of polygala tenuifolia, 8-12 parts of monkshood, 8-12 parts of asarum, 20-30 parts of pulp of dogwood fruit, 30-40 parts of longan aril and 15-22 parts of rhizoma alismatis. The traditional Chinese medicine capsule for preventing or treating ED of middle-aged and elderly men becomes effective rapidly, has good curative effect, can help men maintain long time in erection, and can well improve the sexual capacity of the middle-aged and elderly men.
Owner:广州恒健健康产业有限公司
A kind of Yanhuning enteric-coated preparation and its preparation method
ActiveCN107982241BImprove Medication AdherenceReduce allergic reactionsOrganic active ingredientsAntiviralsOral medicationPharmaceutical sciences
The invention belongs to the field of medicine processing, and particularly relates to a potassium sodium dehydroandrographolide succinate enteric-coated preparation and a preparation method. The preparation method comprises the specific steps of forming a specific formula based on the effective component potassium sodium dehydroandrographolide succinate and auxiliary materials acceptable in pharmaceutical science, coating an isolation layer and coating an enteric-coated layer through a specific processing technology, then adding suitable auxiliary materials so as to prepare an enteric-coatedcapsule, enteric-coated particles and enteric-coated dry suspension. The refinement method for potassium sodium dehydroandrographolide succinate greatly reduces impurities and lowers occurrence rate of side effects; the special preparation process and parameter for producing the potassium sodium dehydroandrographolide succinate enteric-coated preparation can effectively protect active components of potassium sodium dehydroandrographolide succinate, thereby guaranteeing the medicine effect of the finished product and improving the bioavailability of oral potassium sodium dehydroandrographolidesuccinate. The preparation method has easy steps, is easy to operate and is suitable for industrial production.
Owner:HUANGSHAN C KING PHARMA
Medicine compounds for treating diabetic nephropathy
The invention provides a novel medical composite for treating diabetic and nephropathy, which comprises insulin sensitizer and endothelin receptor blocker. The invention scientifically combines two medicines with complete different mechanisms of action so as to reach the target of mechanism complementation, mutual coordination, enhancement of treatment effect and rational usage of medicine. The novel medical composite for treating the diabetic and the nephropathy not only has good coordination in reducing blood sugar, but also achieves quite good coordination effect on protecting kidney. The novel medical composite for treating the diabetic and the nephropathy is probably a new breakthrough of the method for treating the diabetic nephropathy.
Owner:LUNAN PHARMA GROUP CORPORATION
Ciona intestinalis polypeptide and preparation method thereof
The invention belongs to the filed of pharmaceutical sciences and particularly relates to ciona intestinalis polypeptide and a preparation method thereof. The ciona intestinalis polypeptide has the N- terminal sequence of YQPDKFMLRGELRNN, the molecular weight of 5931Da and the isoelectric point of 7.25. The preparation method of the ciona intestinalis polypeptide comprises the following steps: precipitating fresh ciona intestinalis by using 10-90% acetone, dialyzing and desalting active components, and purifying by adopting ion-exchange chromatography, gel filtration chromatography and HPLC (high-performance liquid chromatography) to obtain the ciona intestinalis polypeptide which has the molecular weight of 5931Da. The in vivo and in vitro activity experiments verify and confirm that the application of the ciona intestinalis polypeptide to malignant tumor prevention and treatment.
Owner:INST OF OCEANOLOGY - CHINESE ACAD OF SCI
Doxycycline hydrochloride dual-release preparation and preparation method thereof
ActiveCN102579408BImprove stabilityImprove bioavailabilityAntibacterial agentsTetracycline active ingredientsFormularyImmediate release
Owner:ZHONGSHUAI PHARMA SCI & TECH CO LTD
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