The invention discloses an automatic tire charging control device, which comprises a power supply, a MCU (microprocessor control unit), an LCD screen, a control panel, an illumination lamp, a backlight lamp, an electric control valve, a limit switch, a manual charge switch, a pressure sensor, a buzzer, an LED state indicator lamp, a manual exhaust valve, and an air pressure input and output interfaces. The device can be used for charging a tire respectively by using two control air paths for manual charging and automatic charging. Before the preparation for automatic charging, the charging pressure of the device is preset and the charging process can be controlled in real time, thus achieving timely detection of set pressure, discharge and accurate electronic metering for the automatic charging process, preventing the occurrence of overpressure or underpressure, and achieving pressure setting, measurement and accuracy control of the charging process to meet the charging requirement of different tires. The device may also be used for other occasions requiring accurate charging other than tires.