123 results about "Laboratory rat" patented technology

The invention relates to antrodia cinnamomea extract liquor for reducing blood alcohol concentration. The antrodia cinnamomea extract liquor comprises maleic imide compounds extracted from oil in a cracked cell wall of antrodia cinnamomea mycelium as an effective ingredient, and mixed with a certain amount of edible oil to form a solution form, wherein the edible oil and the effective ingredient are mixed according to the weight ratio of (9:1) to (7:3). Therefore, the activity of alcohol dehydrogenase in the body of a small laboratory rat fed by the antrodia cinnamomea extract liquor disclosed by the invention is obviously increased by about 50-60% relatively, and the alcohol concentration in the blood is also obviously reduced by about 30-40% relatively.

The invention relates to the field of laboratory mouse motion recognition, and discloses a laboratory mouse sniffing motion recognition method, module and system, and the method comprises the steps: collecting laboratory mouse video data; determining key points of the shape and posture of the laboratory mouse, and constructing a key point model; generating a key point identification module according to the experimental mouse video data and the key point model; and using the key point identification module to identify the sniffing action of the laboratory mouse. The identification module comprises a video acquisition sub-module, a key point model construction sub-module and a key point identification module generation sub-module. The identification system comprises a box body, a diffuse reflection plate, a lining plate, an illumination device and an identification module. According to the invention, the sniffing action of the laboratory mouse is identified based on the attitude data ofthe laboratory mouse, so that the sniffing action and attitude change of the laboratory mouse can be accurately and efficiently identified in real time; shadow-free laboratory mouse video data can becollected, accurate video data collection is guaranteed, and automatic recognition of laboratory mouse sniffing actions is achieved.

The invention relates to the technical field of animal blood sampling equipment and particularly discloses a laboratory rat tail cutting blood sampling device. The laboratory rat tail cutting blood sampling device comprises a latex cover, a detachable glass tube, a conical groove, an air suction hole, a vacuum surrounding wall, an exhaust hole, a bottom adjusting device and a passing hole. According to the laboratory rat tail cutting blood sampling device, the vacuum principle is mainly used, air in a bottle is sucked, so that negative pressure is formed in the bottle, blood can flow out soon under the action of negative pressure, and thus the purpose of carrying out multiple times and a large amount of blood sampling on a laboratory rat is achieved; the blood sampling device is provided with the vacuum surrounding wall so that blood back jetting due to air leakage can be avoided, the height of the bottom of the blood sampling device can be adjusted according to the length of different tails through the bottom adjustor, and the blood sampling device is easy and convenient to use and capable of saving time.

The invention relates to a dynamic rat weight loss training running platform and a control system thereof. The dynamic rat weight loss training running platform comprises a treadmill, a dynamic weightloss support device and a control system, wherein the treadmill comprises a case body and an electronic runway; the electronic runway is mounted at the upper end of the case body; the case body is internally provided with a speed adjusting motor; a transmission mechanism which is driven by the speed adjusting motor to implement transmission is arranged on the outer side of the case body; the transmission mechanism is used for driving the electronic runway to move; mounting plates are arranged on both sides and at the upper end of the case body; the dynamic weight loss support device is used for providing support and position adjustment on experiment rats; and in the training process of the experiment rats, in case of gravity center fluctuation, the motor is rotated forwards or reversely along with gravity center fluctuation, and then weight loss force can be kept constant. The control system is used for implementing systematic control on the whole device. By adopting the dynamic rat weight loss training running platform and the control system thereof, a weight loss treatment method with the combination of running platform training and weight loss support can be applied to rats suffering from dyskinesia of hind legs, and experiment bases can be also provided for research on spinal cord injury.

The invention relates to a laboratory mouse monitoring system. The laboratory mouse monitoring system comprises a box body, a body weight monitoring unit, a water drinking unit, a diet unit, a track monitoring unit, a food recovery unit and a control unit. The laboratory mouse monitoring system has the advantages that through the double arrangement of the diet unit and the food recovery unit, the diet weight of each laboratory mouse in the box body each time can be accurately measured, and measurement errors are reduced; by improving the weighing of the water drinking unit, the water drinking amount of each laboratory mouse in the box body each time can be accurately obtained without manual repeated measurement, and the water drinking amount per hour and/or every day can be conveniently counted; motion tracks of the laboratory mice are monitored through the track monitoring unit, the structure is simple, and the motion amount of each laboratory mouse in the box body is accurately obtained.

The invention discloses a full-angle adjusting and fixing device for a high-precision experiment of an ophthalmic laboratory mouse. The full-angle adjusting and fixing device comprises an X-axis sliding block, an X-axis adjusting plate, a Y-axis sliding block, a Z-axis adjusting device and an experiment table assembly which are sequentially arranged from bottom to top, wherein the Y-axis sliding block is composed of a right-angle sliding block I and a right-angle sliding block II; the right-angle sliding block I and the right-angle sliding block II are arranged on the X-axis adjusting plate and are symmetrically distributed; the Y-axis adjusting plate is further clamped between the X-axis adjusting plate and the Y-axis sliding block; the Z-axis adjusting device comprises a rhombic retractable frame, a vertical fixing rod I, a vertical fixing rod II and a horizontal fixing rod; the bottom of the rhombic retractable frame is arranged on the Y-axis adjusting plate and a fixed platform isarranged at the top of the rhombic retractable frame; the bottoms of the vertical fixing rod I and the vertical fixing rod II are arranged on the Y-axis adjusting plate; the fixed platform, the vertical fixing rod I and the vertical fixing rod II are connected through the horizontal fixing rod; and the experiment table assembly is arranged above the fixed platform.

A garbage deodorant is prepared from substances in parts by mass as follows: 10-20 parts of a plant hydrated extract, 30-50 parts of edible mushroom waste and 5-10 parts of a microbial agent. The garbage deodorant has an effective application in the aspect of deodorization of stale refuse or domestic organic garbage. The plant deodorant product is toxic-free and harmless and has no irritation. Experiments through laboratory rats and little white rabbits prove that the deodorant has no transoral toxicity or irritation to skin. The efficient compound microbial deodorant for a garbage dump is lowin cost, high in efficiency, wide in application and very practical in specific production.

A composition for culturing the spleen lymphocytes of laboratory rats comprises an RPMI-1640 culture medium, and concanavalin A, phytohemagglutinin, beta-mercaptoethanol, mannitol, sodium azide, dimethyl sulfoxide and the like are further added into the RPMI-1640 culture medium. Test results prove that the composition can achieve the purpose of maintaining in-vitro long-term proliferation of rat lymphocytes, the number of lymphocytes required by fundamental researches can be achieved through proper proliferation, and the ratio of T cells to B cells is kept unchanged.

The invention relates to a multifunctional brain stereotaxic device. The device includes a fixing mechanism, a three-dimensional location mechanism and an auxiliary mechanism; the fixing mechanism, the three-dimensional location mechanism and the auxiliary mechanism are arranged on a base plate; the three-dimensional location mechanism is arranged above the fixing mechanism; the base plate is provided with a horizontal sliding groove; and the auxiliary mechanism is slidingly arranged in the horizontal sliding groove, and can slide to the upper part of the fixing mechanism and the lower part ofthe three-dimensional location mechanism. The device is scientific and reasonable in design and convenient in using, utilizes the fixing mechanism and the three-dimensional location mechanism to realize the fixing of an experimental rat, and can precisely and effectively perform adjusting and fixing on a three-dimensional coordinate; through the arrangement of a rotary limit disc, the device canbe suitable for drill bits and micro-syringes with various specifications, so that experiment accuracy and efficiency can be effectively enhanced; the supporting on the head skin of the experimental rat can be realized through an experimental supporting unit and an auxiliary unit of the auxiliary mechanism; through the auxiliary unit, the collection of residual blood and the monitoring on the heart of the experimental rat can be realized; and therefore, the integrated multifunctional brain stereotaxic device has high application values and good actual use effect.

The invention relates to the field of laboratory mouse feed, and particularly discloses immunodeficient mouse feed. The immunodeficient mouse feed is prepared from the following raw materials in partsby weight: 80-90 parts of corn flour, 4-8 parts of bran, 5-9 parts of soybean meal, 1-2 parts of beer yeast, 5-8 parts of vegetable oil, 0.001-0.003 part of organic zinc, 0.001-0.002 part of selenoprotein, 0.2-0.5 part of methionine, 0.2-0.5 part of lysine, 0.1-0.2 part of vitamin A, 0.1-0.2 part of vitamin B6, 0.01-0.02 part of ferrous sulfate and 0.08-0.12 part of calcium bicarbonate, wherein the organic zinc is prepared as follows: iminodiacetonitrile reacts with epoxy chloropropane, then an obtained product reacts with chitosan oligosaccharide, a generated compound is hydrolyzed, and thencoordination reaction with zinc ions is conducted. The immunodeficient mouse feed has the advantage of improving the reproductive rate of immunodeficient mice. In addition, the invention further provides a preparation method of the immunodeficient mouse feed.

The invention provides a method for determining tissue distribution of MSC. The method comprises the following steps of (1) infusing human mesenchymal stem cells into a laboratory mouse body, sampling organs or tissues to be monitored at regular intervals, and extracting DNA (deoxyribonucleic acid) samples; (2) extracting DNA from the determined number of human mesenchymal stem cells and diluting the DNA into DNA solutions with a series of concentrations; (3) carrying out real-time fluorescent quantitative PCR (Polymerase Chain Reaction) by taking the sequences as shown in SEQ ID NO: 1 and SEQ ID NO: 2 as primers and taking the DNA sample in the step (1) and the DNA solution in the step (2) as templates; and (4) making a standard curve according to the CT values of the DNA solutions with the series concentrations in the step (2), and calculating the number of the DNA samples in the step (1). According to absolute quantification of the tissue mesenchymal stem cells, the colonization rate of the mesenchymal stem cells in each tissue and the metabolism condition of the mesenchymal stem cells in each tissue along with time in the body can be detected, and a reference basis is provided for designing the administration route and dosage in a clinical scheme.