The invention discloses feed for gene editing laboratory mice. The feed is prepared from components in parts by weight as follows: 30-35 parts of corn, 10-15 parts of wheat, 15-20 parts of soybean meal, 5-12 parts of broken rice, 3-10 parts of fish meal, 1-5 parts of oil, 2-9 parts of a yeast hydrolysate, 0.8-1.2parts of stone powder, 1-2 parts of calcium hydrogen phosphate, 0.5-1 part of compound minerals, 0.1-0.5 parts of decavitamin, 0.1-0.2 parts of methionine and 0.1-0.2 parts of lysine. The feed has balanced nutrition and good palatability and can increase the feed intake of the gene editing laboratory mice, promote growth and breeding and significantly increase the survival rate of the gene editing laboratory mice, the nutrition index of the feed meets the nutrition index of national standard GB14924.3-2010 of Complete Nutritional Feed for Laboratory Animals, the hygienic index meets the hygienic index requirements of national standard GB14924.1-2010 of Complete Nutritional Feed for Laboratory Animals, and the feed for the gene editing laboratory mice has bright application prospects.