Awake laboratory mouse bladder pressure measuring catheter suite

Abstract

The invention discloses an awake laboratory mouse bladder pressure measuring catheter suite which comprises a bladder cannula and a lengthening component. A guide wire is arranged inside the bladder cannula. The front end of the guide wire is designed to be a conic sharp end and the rear end of the bladder cannula is provided with a closing clamp. The lengthening component comprises a PE-50 catheter, a double-head connecting tube and a three-way catheter. One end of the PE-50 catheter is connected with the double-head connecting tube and the other end of the PE-50 catheter is connected with one catheter opening of the three-way catheter. The double-head connecting tube is connected with the rear end of the bladder cannula and fixed through the closing clamp. The awake laboratory mouse bladder pressure measuring catheter suite has the advantages that the inserting end of the bladder cannula can be fixed through an automatic curling structure generated after the guide wire of the inserting end of the bladder cannula is extracted, and the detection success rate and detection result accuracy are improved; by the use of the suite, operation difficulty is greatly lowered, experiment efficiency is improved, and damage to the skin and the bladder wall of an experiment mouse is reduced.

Description

technical field [0001] The invention relates to a bladder pressure measuring catheter set for conscious experimental mice, which belongs to the technical field of medical equipment. Background technique [0002] In the field of urological animal experiments, urodynamic examination is an important part of evaluating the urinary system function of experimental animals. Urodynamic examination is based on the basic principles and methods of fluid mechanics and electrophysiology to detect the pressure, flow rate and physiological electrical activity of various parts of the urinary tract, so as to reflect the function of the urinary tract to excrete urine and related innervation nerves. Among them, filling cystometry is a relatively mature and widely used measurement method. In this method, water is artificially injected into the bladder of experimental animals by using the perfusion pipeline of the urodynamic measurement system (such as Powerlab or Urodynamic), and the pressure ...

AI Technical Summary

Problems solved by technology

These methods not only add cumbersomeness to the experiment, but also do not work well

The reason is that on the one hand, the PE-50 catheter is slender and smooth and not easy to fix;

These factors make the PE-50 catheter easy to slip out of the bladder, resulting in measurement failure and even death of the experimental mice

[0006] 2. It is difficult to insert the PE-50 catheter into the bladder

This operation is not only tedious and difficult, but also extremely traumatic to the experimental mice

Images