The invention discloses a method for extracting
chlorogenic acid and
isochlorogenic acid from
gynura procumbens. The method comprises the following steps of
drying and smashing fresh
gynura procumbensleaves, and obtaining
powder; mixing the
powder and an
ethanol solution, adopting ultrasonic extraction to obtain an extracting solution, and then centrifuging, filtering and concentrating to obtaina turbid dark green concentrated solution; adding a
clarifying agent into the concentrated solution for clarifying; adding modified
silicon dioxide
pellets into the clarified concentrated solution, de-coloring, and enabling the color of the concentrated solution to change into light gray from dark green; adding absolute ethyl
alcohol into the light-gray concentrated solution, and eliminating carbohydrates; adsorbing the carbohydrates-eliminated through a middle0high-pressure
chromatographic column; after completely adsorbing, desorbing in a classification way, concentrating, and
drying to obtain a
chlorogenic acid finished product
dry powder and
isochlorogenic acid mixture. The method provided by the invention is simple in process, convenient to operate, low in cost, free of harmful
solvent, high in product purity, better in purification and
impurity cleaning effects, energy saving, environmental-friendly, high in production safety, and suitable for industrial production, and has a favorable market prospect.