Method for establishing fingerprint of flos lonicerae medicinal preparation
A technology of pharmaceutical preparations and fingerprints, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of inability to detect and control quality, difficult to apply to production practice, and time-consuming, so as to improve safety, stability, and stability High, high-precision effects
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0055] In the following examples and experimental examples, the preparation method of honeysuckle formula granules is as follows: taking honeysuckle, heating and refluxing extraction for 2 times, adding 15 weight times of water for 0.5h for the first time, and adding 13 weight times of water for the second time to extract 0.5h, filter, combine the filtrate, concentrate the filtrate to 60°C with a relative density of 1.05-1.10, add conventional auxiliary materials, and make granules according to conventional technology.
Embodiment 2
[0057] The present embodiment establishes the method for the fingerprint of honeysuckle formula granules, comprising the following steps:
[0058] (1) Take 0.4 g of the medicinal preparation of honeysuckle to be tested, accurately weigh it, accurately add 25 mL of 50% methanol aqueous solution, weigh it, heat under reflux for extraction or ultrasonic extraction for 30 minutes, let it cool, weigh it again, and take 50% methanol The water solution supplements the lost weight, shakes well, filters, and takes the subsequent filtrate as the test solution;
[0059] (2) Precisely weigh the chlorogenic acid reference substance, add 50% methanol aqueous solution to make a solution containing 0.00004 g per 1 mL, shake well, and use it as the reference substance A solution;
[0060] Precisely weigh the reference substance of luteolin, add 50% methanol aqueous solution to make a solution containing 0.00004g per 1mL, shake well, and use it as the reference substance B solution;
[0061] P...
Embodiment 3
[0066] The present embodiment establishes the method for the fingerprint of honeysuckle formula granules, comprising the following steps:
[0067] (1) Take 0.3 g of the medicinal preparation of honeysuckle to be tested, accurately weigh it, accurately add 20 mL of 60% methanol aqueous solution, weigh it, heat under reflux for extraction or ultrasonic extraction for 40 minutes, let it cool, weigh it again, and take 60% methanol The water solution supplements the lost weight, shakes well, filters, and takes the subsequent filtrate as the test solution;
[0068] (2) Precisely weigh the chlorogenic acid reference substance, add 60% methanol aqueous solution to make a solution containing 0.00002 g per 1 mL, shake well, and use it as the reference substance A solution;
[0069] Precisely weigh luteolin reference substance, add 60% methanol aqueous solution to make a solution containing 0.00002g per 1mL, shake well, and use it as reference substance B solution;
[0070] Accurately w...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com