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87 results about "Interphase Cell" patented technology

Interphase is the phase of the cell cycle in which a typical cell spends most of its life. During this phase, the cell copies its DNA in preparation for mitosis. Interphase is the 'daily living' or metabolic phase of the cell, in which the cell obtains nutrients and metabolizes them, grows, reads its DNA, and conducts other "normal" cell functions.

Formulations for cell-schedule dependent anticancer agents

The present invention provides a flowable composition suitable for use as a controlled release implant. The composition includes: (a) a biodegradable, biocompatible thermoplastic polymer that is at least substantially insoluble in aqueous medium, water or body fluid; (b) a cell-cycle dependent biological agent, a schedule-dependent biological agent, a metabolite thereof, a pharmaceutically acceptable salt thereof, or a prodrug thereof; and (c) a biocompatible organic liquid, at standard temperature and pressure, in which the thermoplastic polymer is soluble. The present invention also provides a method of treating cancer in a mammal. The present invention also provides a method of blocking, impeding, or otherwise interfering with cell cycle progression at the G1-phase, G1 / S interphase, S-phase, G2 / M interface or M-phase of the cell cycle in a mammal. The methods includes administering to a mammal an effective amount of a flowable composition of the present invention.
Owner:QLT USA INC

Polymer electrolyte, intercalation compounds and electrodes for batteries

Solid battery components are provided. A block copolymeric electrolyte is non-crosslinked and non-glassy through the entire range of typical battery service temperatures, that is, through the entire range of at least from about 0° C. to about 70° C. The chains of which the copolymer is made each include at least one ionically-conductive block and at least one second block immiscible with the ionically-conductive block. The chains form an amorphous association and are arranged in an ordered nanostructure including a continuous matrix of amorphous ionically-conductive domains and amorphous second domains that are immiscible with the ionically-conductive domains. A compound is provided that has a formula of LixMyNzO2. M and N are each metal atoms or a main group elements, and x, y and z are each numbers from about 0 to about 1. y and z are chosen such that a formal charge on the MyNz portion of the compound is (4-x). In certain embodiments, these compounds are used in the cathodes of rechargeable batteries. The present invention also includes methods of predicting the potential utility of metal dichalgogenide compounds for use in lithium intercalation compounds. It also provides methods for processing lithium intercalation oxides with the structure and compositional homogeneity necessary to realize the increased formation energies of said compounds. An article is made of a dimensionally-stable, interpenetrating microstructure of a first phase including a first component and a second phase, immiscible with the first phase, including a second component. The first and second phases define interphase boundaries between them, and at least one particle is positioned between a first phase and a second phase at an interphase boundary. When the first and second phases are electronically-conductive and ionically-conductive polymers, respectively, and the particles are ion host particles, the arrangement is an electrode of a battery.
Owner:MASSACHUSETTS INST OF TECH

Automated segmentation, classification, and tracking of cell nuclei in time-lapse microscopy

InactiveUS20060127881A1Efficient dynamic cell imaging studyIncrease capacityImage enhancementImage analysisAutomated segmentationInterphase Cell
Methods and apparatus are provided for the automated analysis of images of living cells acquired by time-lapse microscopy. The new methods and apparatus can be used for the segmentation, classification and tracking of individual cells in a cell population, and for the extraction of biologically significant features from the cell images. Based upon certain extracted features, the inventive image analysis methods can characterize a cell as mitotic or interphase and / or can classify a cell into one of the following mitotic phases: prophase, metaphase, arrested metaphase, and anaphase with high accuracy.
Owner:THE BRIGHAM & WOMENS HOSPITAL INC

Fiber-reinforced ceramic composite material comprising a matrix with a nanolayered microstructure

A fiber-reinforced ceramic matrix composite material exhibiting increased matrix cracking strength and fracture toughness is produced by sequentially depositing a plurality of 5-500 nanometer-thick layers of a primary ceramic matrix material phase periodically separated by 1-100 nanometer-thick intermediate layers of a secondary matrix material phase onto the reinforcing fibers upon their consolidation. The resultant nanolayered matrix enhances the resistance to the onset of matrix cracking, thus increasing the useful design strength of the ceramic matrix composite material. The nanolayered microstructure of the matrix constituent also provides a unique resistance to matrix crack propagation. Through extensive inter-layer matrix fracture, debonding and slip, internal matrix microcracks are effectively diverted and / or blunted prior to their approach towards the reinforcing fiber, thus increasing the apparent toughness of the matrix constituent. This unique toughening mechanism serves to dampen energetic co-planar macrocrack propagation typically observed in conventionally manufactured ceramic matrix composites wherein matrix cracks are usually deflected at the fiber / matrix interphase region.
Owner:ROLLS ROYCE HIGH TEMPERATURE COMPOSITES INC

Polymeric core-shell nanoparticles with interphase region

A polymeric nanoparticle composition is provided. The nanoparticle may be of a core / shell configuration with an interphase region connecting the core and the shell. The mean average diameter of the polymer nanoparticles may be less than about 250 nm. The size, composition, and / or configuration of the interphase region may be varied to achieve desired physical and / or chemical properties of the resulting polymeric nanoparticles, and of the compositions into which the nanoparticles are compounded.
Owner:BRIDGESTONE CORP

Negative pole piece for lithium battery, preparation method of negative pole piece and lithium battery with negative pole piece

The invention belongs to the technical field of lithium batteries, and in particular relates to a negative pole piece for a lithium battery. The negative pole piece comprises a current collector and a graphitic layer arranged on the current collector, and further comprises a protecting layer and a metal lithium layer, wherein the protecting layer is arranged on the graphitic layer; and the metal lithium layer is arranged on the protecting layer. Compared with the prior art, the negative pole piece is provided with the protecting layer on the surface of the graphitic layer, and the metal lithium layer on the surface of the protecting layer, when the negative pole piece is assembled into the lithium battery, metal lithium powder diffuses in the negative pole piece in an electrochemical manner, so that the first time efficiency of a negative pole is improved, and moreover, the energy density of the lithium battery is increased, and the capacity of the lithium battery is enhanced; and at the same time, the protecting layer is equivalent to a buffer layer which can effectively prevent the graphitic layer from internally peeling off, so that the stability of an SEI (Solid Electrolyte Interphase) membrane on the surface of the negative pole piece is improved, and the circulation performance of the battery is improved. In addition, the invention also discloses a preparation method of the negative pole piece and a lithium battery with the negative pole piece.
Owner:DONGGUAN AMPEREX TECH

Inverter Apparatus

An objective of the present invention is to improve current detection accuracy and to reduce noise of carrier frequency. A motor apparatus and a motor drive apparatus calculate motor currents Iu, Iv, and Iw using a DC bus current detected value Idc of an inverter and control a magnitude and a phase of an applied voltage of a motor to drive the motor. A carrier adjuster decreases a carrier frequency Fc of the inverter if a motor output is relatively larger and that increases the carrier frequency Fc of the inverter if the motor output is relatively smaller. A pulse shift adjuster shifts an interphase waveform of a PWM pulse according to the carrier frequency Fc.
Owner:HITACHI ASTEMO LTD

Polymer electrolyte, intercalation compounds and electrodes for batteries

Solid battery components are provided. A block copolymeric electrolyte is non-crosslinked and non-glassy through the entire range of typical battery service temperatures, that is, through the entire range of at least from about 0° C. to about 70° C. The chains of which the copolymer is made each include at least one ionically-conductive block and at least one second block immiscible with the ionically-conductive block. The chains form an amorphous association and are arranged in an ordered nanostructure including a continuous matrix of amorphous ionically-conductive domains and amorphous second domains that are immiscible with the ionically-conductive domains. A compound is provided that has a formula of LixMyNzO2. M and N are each metal atoms or a main group elements, and x, y and z are each numbers from about 0 to about 1. y and z are chosen such that a formal charge on the MyNz portion of the compound is (4−x). In certain embodiments, these compounds are used in the cathodes of rechargeable batteries. The present invention also includes methods of predicting the potential utility of metal dichalgogenide compounds for use in lithium intercalation compounds. It also provides methods for processing lithium intercalation oxides with the structure and compositional homogeneity necessary to realize the increased formation energies of said compounds. An article is made of a dimensionally-stable, interpenetrating microstructure of a first phase including a first component and a second phase, immiscible with the first phase, including a second component. The first and second phases define interphase boundaries between them, and at least one particle is positioned between a first phase and a second phase at an interphase boundary. When the first and second phases are electronically-conductive and ionically-conductive polymers, respectively, and the particles are ion host particles, the arrangement is an electrode of a battery.
Owner:MASSACHUSETTS INST OF TECH

Composite-structure bearingless switched reluctance motor and control method thereof

The invention relates to a composite-structure bearingless switched reluctance motor and a control method thereof and belongs to the field of bearingless switched reluctance motors and control methods thereof. A torque stator and a levitation stator are axially stacked to form a stator; a winding is wound on teeth of the stator and passes the torque stator and the levitation stator, and the winding is wound in a central winding manner; a rotor comprises a torque rotor and a levitation rotor, the torque rotor and the levitation rotor are axially stacked in the stator, the torque rotor is located below the torque stator, the torque stator and the torque rotor are equal in axial length, and the levitation stator corresponds to the levitation rotor while the levitation stator and the levitation rotor are equal in axial length; the levitation stator is in a pole shoe structure, and the polar arc angle of the levitation stator is larger than that of the torque stator. Levitation and torque decoupled control is achieved; the control method is simple; radial bearing force is large; the motor is fine in levitating performance. Levitation control is achieved by minimum inductance zone; the levitating current has low effect on torque current, and interphase coupling effect is low.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS

Novel enhanced electrochemical cells with solid-electrolyte interphase promoters

An electrochemical cell with an alkali metal containing anode having high discharge capacity, charge efficiency and low self-discharge. The addition of at least one nitramide or dinitramide salt of a metal cation to the electrochemical cell electrolyte unexpectedly lowers first cycle irreversible capacity, adds higher cycle life, lowers self-discharge and beneficially addresses several additional degrees of freedom with respect to electrolyte solvent selection while providing higher charge capacity. Additives include the lithium metal salts of nitramide or dinitramide, and the electrolyte consists essentially of a lithium metal salt dissolved in a at least one of an aqueous solvent, molten salt solvent system and a non-aqueous solvent mixture of at least one of organic ethers, esters, carbonates, acetals.
Owner:MATERIAL METHODS

System for automatically controlling winding tension of transformer coil

InactiveCN102360930AAchieving Resistance Unbalance RatioCoils manufactureFrequency changerLine resistance
The invention relates to a system for automatically controlling winding tension of a transformer coil. The system comprises an uncoiler, a recoiler, an uncoilder rotary torque adjusting device and a recoiler rotary torque adjusting device, wherein the uncoilder rotary torque adjusting device comprises an uncoiling drum winding diameter detection component and an adjustment controller; the uncoiling drum coiling diameter detection component is used for detecting the coiling diameter variation of the uncoiling drum; the adjustment controller is used for dynamically adjusting the rotary torque of the uncoiling drum according to the coiling diameter variation, so that the current tension of a winding material wound on the uncoiling drum in the rotating process is in the error range of the preset tension value; the recoiler rotary torque adjusting device comprises a coil coiling diameter detection component and a transducer; the coil coiling diameter detection component is used for detecting the coiling diameter variation of a winding carrier; and the transducer is used for dynamically adjusting the rotary torque of the winding carrier, so that the tension of a winding material wound on the winding carrier is constant. The resistance unbalance ratio of the transformer coil can meet the related requirement of the national standard, for example, the interphase resistance unbalance ratio is less than or equal to 4 percent and the line resistance unbalance ratio is less than or equal to 2 percent.
Owner:EMERSON NETWORK POWER CO LTD

Sodium supplementing method for sodium-ion battery and sodium-ion battery

The invention discloses a sodium supplementing method for a sodium-ion battery. The sodium supplementing method includes: mixing a metal element and a sodium salt according to a certain molar ratio, adding the mixture as the anode additive into an anode active material to prepare a sodium-ion battery anode plate, and assembling into a battery; in a battery formation stage, controlling an initial charge voltage range to allow the metal element to have complete reaction with the sodium salt so as to release sodium ions from the anode additive to a cathode plate to form an SEI (solid electrolyte interphase) film; controlling a battery cyclic charge-discharge voltage range to allow the sodium-ion battery to enter a normal charge-discharge use state, wherein the metal element in the additive exists in the battery in the form of a metal compound. The sodium supplementing method for the sodium-ion battery has the advantages that the loss of active sodium ions in the anode material is reduced, the initial coulombic efficiency of the sodium-ion battery is increased, and the method is safe, practical and convenient to operate.
Owner:SUNWODA ELECTRIC VEHICLE BATTERY CO LTD

Strain tower with shape like Chinese character 'gan' of compact transmission line

The invention relates to a strain tower with a shape like a Chinese character 'gan' of a compact transmission line, comprising tower legs (8), a tower body (7), a tower head (13), a conducting wire strain string (11), a common jumper suspension string (9) and a united jumper suspension string (10), wherein a second conducting wire strain string (11-2) is connected with an upper-phase jumper suspension wire clamp (10-3) of the interphase united jumper string (10) by a second jumper (12-2), and a third conducting wire strain string (11-3) is connected with a lower-phase jumper suspension wire clamp (10-7) of the interphase united jumper string (10) by a third jumper (12-3). The invention has simple structure, increases the earth height of the lower-phase jumper, solves the detects of higher calling height, complicated structure and high self cost of the traditional compact type strain tower structure and reduces tree felling and earth and rock extraction. The compact ultra-high-voltage transmission line has more advanced technology, is more reasonable in economy and more environment-friendly in ecology.
Owner:CENT SOUTHERN CHINA ELECTRIC POWER DESIGN INST CHINA POWER ENG CONSULTING GROUP CORP

Multi-power-supply gridconnected system control method based on modularized multilevel convertor

The invention discloses a multi-power-supply gridconnected system control method based on a modularized multilevel convertor. The multi-power-supply gridconnected system control method comprises the following steps: the power control part of the modularized multilevel convertor generates a sinusoidal modulation wave; the sinusoidal modulated wave is sequentially subject to direct current supply control, an interphase circumfluence control and a gridconnected current direct current component inhibit control to superpose corresponding regulation value, and is finally subject to carrier wave dephasing SPWM modulation to generate a switch driving signal. The multi-power-supply gridconnected system control method can flexibly control the interphase circumfluence according to the operation state of the multi-power-supply gridconnected system.
Owner:SHANDONG UNIV

Battery system and evaluation method for battery

A battery system 1 includes a secondary battery 10 including a positive electrode 11, a negative electrode 15, and electrolytes 12 and 14, a storing section 23 configured to store peculiar information of the secondary battery 10 measured in advance including an initial resistance value and an evaluation frequency, a power supply section 20 configured to apply an alternating current signal having the evaluation frequency stored in the storing section 23 to the secondary battery 10, a measuring section 22 configured to measure impedance of a solid electrolyte interphase 17 of the secondary battery 10 from the alternating current signal, and a calculating section 24 configured to calculate at least one of a deterioration degree and a charging depth of the secondary battery 10 from the impedance and the peculiar information.
Owner:WASEDA UNIV

Methods and uses of leptin in immune modulation and hepatocellular carcinoma

Leptin was previously demonstrated to exert potent immune modulatory properties in several immune mediated disorders. The aim of the study was to determine leptin's anti-tumor effect in a murine model of human hepatocellular carcinoma (HCC). In vivo, Athymic T cell deficient (nude) mice transplanted with 1×106 human Hep3B cells, followed by administration of two daily intraperitoneal doses of 0.5 mg / gram leptin for 6 weeks. Leptin administration induced a significant reduction in tumor size and improved survival in nude mice. Histologically, tumors of leptin-administered mice featured increased inflammatory exudate in interphase areas. Leptin-induced tumor suppression was associated with a significant increase in peripheral natural killer (NK) cell number. Splenocytes from leptin-treated mice featured decreased expression of CIS mRNA. To determine which lymphocyte subset is a prerequisite for the anti tumor effect of leptin, T&B cell deficient (Scid) mice and T,B& NK deficient (Scid-Beige) mice were subcutaneously implanted with Hep3B tumor cells, with and without the daily intraperitoneal administration of 0.5 mg / gram leptin for 6 weeks. SCID mice featured leptin-associated tumor suppression similar to those of nude mice. In contrast, NK-deficient SCID-Beige mice developed larger tumors. To further establish natural killer cell's central role in mediation of leptin's anti-tumor effect, NK cells were incubated in vitro with increasing doses of leptin, demonstrating a dose-dependent increase in cytotoxic activity. Incubation of leptin with hepatoma cell line was found to induce a dose-dependent reduction in hepatoma cell proliferation, suggesting an additive direct anti-tumor effect. Further synergism in inhibition of hepatoma cell proliferation in vitro was achieved following addition of natural killer cells. HCC cells expressed leptin receptor mRNA, while addition of leptin induced increased mRMA expression of STAT2 and SOCS1 on tumor cell lines. Leptin administration induces a significant suppression of human HCC. This effect is mediated by induction of natural killer cell proliferation and activation, and by direct inhibition of tumor growth. Decreased natural killer cell expression of inhibitory CIS protein and over expression of the anti-proliferative STAT2 and SOCS1 proteins in HCC lines may underline both anti cancerous effects of leptin.
Owner:ENZO THERAPEUTICS

Harmonic cancelling interphase magnetic device

A harmonic cancelling interphase magnetic device (1) comprising a magnetic core of rectangular shape with three wound legs (14) and two non-wound legs (12), wherein the cross-section of said non-wound legs (12) is thinner than the cross-section of said wound legs (14). The magnetic device is designed for a front end multi-pulse rectifier or inverter. Its use enables reduction of the harmonics of the currents absorbed or injected to three-phase power line. Compare to known solutions, cost, material and dimensions of the magnetic device are significantly reduced.
Owner:SCHAFFNER EMV

Interphase insulating sheet of rotating electric machine, and electric compressor

An interphase insulating sheet of a rotating electric machine is disclosed. The interphase insulating sheet includes a first insulating portion arranged between first coil ends of two different phases, a second insulating portion arranged between second coil ends of two different phases, and bridge pieces inserted in slots. The first insulating portion includes a first coupling aid. The second insulating portion includes a second coupling aid. The first coupling aid and the second coupling aid each includes an outer surface facing radially outward of the stator core and an inner surface facing radially inward of the stator core. The first end portion of the bridge piece is located on the outer surface of the first coupling aid, and the second end portion of the bridge piece is located on the inner surface of the second coupling aid.
Owner:TOYOTA IND CORP

Motor positive and negative rotation control circuit

ActiveCN103633888APrevent phase-to-phase short circuitGuaranteed switching timeEmergency protective circuit arrangementsPolyphase induction motor starterSufficient timeEngineering
The invention relates to a motor positive and negative rotation control circuit, comprising a contactor KM, a contactor KM1, a contactor KM2, a contactor KM3, a time relay KT1, a time relay KT2, a positive rotation switch SB3 and a negative rotation switch SB2. When a motor is switched into a negative direction from a positive direction or switched into a positive direction from a negative direction, on one hand, after a main contact KM1-1 of the contactor KM1 or a main contact KM2-1 of the contactor KM2 is completely subjected to arc extinction, the main contact KM2-1 of the contactor KM2 or the main contact KM1-1 of the contactor KM1 is closed under the condition that a main circuit is disconnected, so that the effect is played in protecting the main contact KM1-1 and the main contact KM2-1, and the interphase short circuit in the direction switching process is prevented; on the other hand, enough time is reserved for the motor being subjected to power failure for enabling that the speed of the motor is gradually reduced, so that the risks of damage of the motor and a transmission device are reduced; due to the arrangement of the contactor KM3 which is connected between two phases of a power supply in the main circuit, phase-lack protection can be provided.
Owner:STATE GRID CORP OF CHINA +1

Electric power conversion system

An electric power conversion system includes: a primary electric power conversion circuit including primary right and left arms; a secondary electric power conversion circuit including secondary right and left arms; and a control circuit controlling transfer of electric power between the primary and secondary electric power conversion circuits by magnetically coupling a primary coil to a secondary coil. The control circuit sets an interphase difference in switching between right and left arm lower transistors in the primary electric power conversion circuit and an interphase difference in switching between right and left arm lower transistors in the secondary electric power conversion circuit on the basis of off times of the primary and secondary electric power conversion circuits such that a phase difference between terminal voltage waveforms of the primary and secondary coils is 0 and duty ratios of the terminal voltage waveforms are equal to each other.
Owner:TOYOTA JIDOSHA KK

System and method for power conversion

InactiveUS20150138859A1Reduce common mode signalAc-dc conversionEngineeringMode selection
A power conversion system is presented. The power conversion system includes a power converter. The power converter includes at least two circuits, where each of the at least two circuits includes two or more phase legs, where each of the two or more phase legs includes at least two semiconductor switches. Also, the at least two circuits includes an interphase reactor configured to couple one of the two or more phase legs to at least one other phase leg in the two or more phase legs. Moreover, the power conversion system includes a controller configured to obtain a switching pattern for each of the at least two semiconductor switches of the at least two circuits and selectively switch each of the at least two semiconductor switches based on the obtained switching pattern to reduce a common mode signal in the power conversion system. Method for power conversion is also presented.
Owner:GENERAL ELECTRIC CO

Methane synthesizing method and equipment with slurry bed member

The present invention discloses a method for synthesizing methyl alcohol by using component slurry bed and its equiopment. Said invention utilizes the introduction of specific inert solvent, and makes it and fine granule catalyst and synthetic gas in the reactor form three-phase slurry bed reaction system; and adds internal component and gas distributor in the slurry bed reactor to make bubbles uniformly distribute in the reactor; its operation temp. is easily controlled, and service life of said catalyst is long, under the condition of low operatino gas speed the phase circulation can be increased, the mass transfer heat-transfer can be forcedly intensified, so that the interphase mass transfer speed in the slurry bed reactor can be greatly raised, and its reaction conversion rate can be raised.
Owner:TSINGHUA UNIV

Method of isolating purified RNA with reduced DNA contaminations

The present invention pertains to a method of isolating RNA from a sample comprising RNA, and DNA, comprising: a) adding an acidic denaturing composition comprising a chaotropic agent and phenol to the sample; b) adding a water-insoluble organic solvent and separating the resulting phases thereby forming a multi-phase mixture comprising an aqueous phase, optionally an interphase and an organic phase, wherein the RNA is concentrated in said aqueous phase and DNA and proteins are concentrated in said organic phase and / or in said interphase; and c) isolating said RNA from said aqueous phase, wherein at least one cationic detergent is added before separating the phases. It was found that the addition of at least one cationic detergent considerably reduces the amount of DNA in the aqueous, RNA containing phase. Therefore, the present invention allows to easily isolate pure RNA which comprises considerably less DNA contaminations.
Owner:QIAGEN GMBH

Polymer Films

This invention relates to a non-supported (or free standing) cross linked polymer film obtainable by initiating the polymerization of one or several monomers at an interphase. The interphase may be between two immiscible liquids or at a liquid-gas, solid-gas or solid-liquid interphase. The polymer may be used to facilitate chemical reactions, for separation of substances, as a chromatographic stationary phase, as an adsorbent, in sensors or actuators. It may also be used for drug delivery, as a responsive valve or in artificial muscles. The invention also relates to a method for producing thin film polymers, wherein controlled radical polymerization (CRP) is used to produce a thin film cross-linked polymer at an interface where one of the phases (liquid, solid or gas) can be removed after polymerization and be replaced with another phase (liquid, solid or gas).
Owner:MIP TECH AB

Transformer Neutral Current Suppression Method

The invention aims to provide a method for suppressing the neutral current of a transformer. In the method provided by the invention, a neutral current suppression model is constructed aiming at the influence of a compensation range of reactive power compensation on compensation effects based on the relation among interphase reactive power compensation, relative reactive power compensation and the second side current and load side current of the transformer by leading an optimization theory; and on the premise of ensuring the stability and reliability of compensation, the neutral current suppression is realized by setting constraint conditions and target function weight coefficients in the model. The method provided by the invention determines the optimal reactive power compensation quantity by solving the neutral current suppression model, thereby enabling the compensation effects and the reactive power compensation configuration to be optimal.
Owner:四川得丰电气有限公司
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