36 results about "Experimental drug" patented technology

The invention relates to a chemical laboratory drug placement rack, in particular to a chemical laboratory drug detachable placement rack. The technical problem to be solved is to provide the chemicallaboratory drug detachable placement rack which is easy to assemble and disassemble and can reduce the occupied space. The technical solution of the present invention is the chemical laboratory drugdetachable placement rack, the laboratory drug detachable placement rack comprises a square placement plate, a moving plate, a placing frame, partition plates, a handle, a large roller, a small roller, and the like; the right side of the square placement plate is provided the moving plate, the lower part of the right side of the moving plate is connected with the placing frame, a plurality of partition plates are placed on the placing frame, the handle is connected to the middle of the right side surface of the moving plate, and the handle is located at the front side of the partition plate. The square placement plate and the moving plate of the invention are separated, the partition plates are placed between the left and right placement grooves to place the experimental drug on the partition plates; a clamping ball is inserted into a clamping slot, and the square placement plate and the moving plate can be fixed together, so that the chemical laboratory drug placement rack can be easily assembled and disassembled, and the occupied space can be reduced.

The invention relates to a quantitative taking device, in particular to a quantitative taking device for chemical experiment drugs. The technical problem to be solved is to provide a quantitative taking device for chemical experimental medicines that can reduce labor intensity and improve quantitative taking efficiency. The technical scheme of the present invention is: a quantitative taking device for chemical experimental drugs, including a suction cup base, etc.; a cup that can measure chemical experimental drugs is placed in the middle of the top of the suction cup base, and there are two brackets, which are respectively fixed on the top of the suction cup base. On the left and right sides, the lower hopper that can place the medicine bottle is arranged between the tops of the left and right brackets, and the quantitative device that can measure the chemical experiment medicine is installed at the lower part of the lower hopper. The invention can facilitate users to quantitatively take the chemical experimental medicine through the quantitative device, and can prevent the chemical experimental medicine from overflowing and falling on the ground through the inclined baffle, thereby reducing labor intensity and improving quantitative taking efficiency.

The invention discloses a method for rapidly extracting total RNA from lotus root tissue. The steps are: first, the preparation of experimental medicines and the treatment of experimental supplies; second, the collection of materials, the young leaves of lotus root and the petioles connected with the leaves; the third, extraction, precipitation, and centrifugation to obtain total RNA; the fourth is The identification of total RNA was detected by UV spectrophotometer and formaldehyde-denatured agarose gel electrophoresis respectively. According to the obtained data and electrophoresis results, it was shown that the obtained lotus root tissue total RNA had good integrity, high purity and high yield. The invention has the advantages of simple and convenient experimental process, convenient and safe operation, accurate and effective results and good repeatability, and the method is also suitable for extracting total RNA from plant tissues of other species rich in polysaccharides and polyphenols.

The invention relates to a middle school experimental medicine distribution device which is characterized by comprising a base, two hollow circular discs and a circular plate, wherein a vertical supporting rod is arranged at the middle of the base; a supporting ring is arranged at the middle of the vertical supporting rod; a sleeve hole allowing the supporting rod to penetrate through is formed in the center of each of the two hollow circular discs; the diameter of each of the sleeve holes is smaller than that of the supporting ring; the hollow circular discs adopt hollow structures and the hollow parts of the circular discs adopt fan-shaped structures; the fan-shaped hollow parts of the corresponding hollow circular disc are annularly distributed by taking the center of the circular disc as the circle center; the diameter of the circular plate is greater than or equal to that of each hollow circular disc; a sleeve hole is further formed in the middle of the circular plate; the diameter of the sleeve hole is greater than or equal to that of the supporting ring; the circular plate is composed of two semicircle parts. According to the middle school experimental medicine distribution device provided by the invention, drugs can be partitioned by the medicine distribution device, and partitioned drugs can drop down after the circular plate is taken out, so that the purpose of uniform partition can be achieved.

The invention provides an investigational drug inventory management system applied to research centers, the system comprising a processor and a computer readable storage medium. The system can implement the following steps: judging whether current inventories E of various investigational drugs in a research center are all greater than or equal to a preset safe inventory V of the research center in real time; if not, obtaining the current inventory E and historical data of use of each investigational drug in the research center, and calculating the predicted total number L of dropout people in a prediction period T according to the preset warehouse prediction period T; according to the number N of drugs a preset subject takes upon each visit and a subject visit period of P weeks, calculating the number S of visits in the prediction period of enrolled subjects, the number U of visits in the prediction period of to-be-enrolled subjects and the total number R of drugs to be taken; calculating the drug supply quantity Q in the prediction period; generating a drug transport list according to which warehouses supplement the inventories of the investigational drugs for the research center.

This application involves the use of non-nucleoside HIV-1 reverse transcriptase inhibitor 1-[(2-hydroxyethoxy)-methyl]-6-(phenylthio)thymine (HEPT) as the lead substance, which is combined into clinical The experimental drugs MKC-442 and TNK-651, based on the theory of bioelectron isosterism and hydrogen bonding, designed a new class of molecules with related structures. See general formula I, the definition of each group in the formula is as described in the claims. At the same time, it also relates to the evaluation of the reverse transcriptase activity of the compounds and the application of these compounds as HIV-1 reverse transcriptase inhibitors. The conformation of the synthesized new compound is more conducive to the combination with HIV-1 reverse transcriptase, which is more conducive to its inhibition of reverse transcriptase activity, and becomes a new type of HIV-1 reverse transcriptase inhibitor with high activity and low toxicity agent.

The invention relates to a pesticide composition, and especially relates to an emulsion in water of the pesticide composition for controlling cotton aphids and thrips. The emulsion in water of the pesticide composition for controlling cotton aphids and thrips comprises the following components in percentage by weight: 5-20% of Guadipyr, 5-20% of cyhalothrin, 10-15% of solvent, 4-10% of an emulsifier, 0.2-0.5% of a defoamer, 5-10% of an anti-freezing agent, 2-6% of a disintegrating agent and the balance of water. By compounding the Guadipyr and the cyhalothrin, the resistant cotton aphids can be effectively controlled, the control efficiency is superior to the reference, the lasting period is long, the control effect is up to 90%, and no phytotoxicity is caused to the target crops in the experimental drug scope. According to the emulsion in water of the pesticide composition for controlling cotton aphids and thrips, the defects that the cyhalothrin is relatively bad in environmental friendliness and the Guadipyr is relatively bad in fast-acting property and relatively slow in drug action can be effectively solved.