89 results about "Research center" patented technology

The invention provides a system and methods for the determination of the pharmacogenomic phenotype of any individual or group of individuals, ideally classified to a discrete, specific and defined pharmacogenomic population(s) using machine learning and population structure. Specifically, the invention provides a system that integrates several subsystems, including (1) a system to classify an individual as to pharmacogenomic cohort status using properties of underlying structural elements of the human population based on differences in the variations of specific genes that encode proteins and enzymes involved in the absorption, distribution, metabolism and excretion (ADME) of drugs and xenobiotics, (2) the use of a pre-trained learning machine for classification of a set of electronic health records (EHRs) as to pharmacogenomic phenotype in lieu of genotype data contained in the set of EHRs, (3) a system for prediction of pharmacological risk within an inpatient setting using the system of the invention, (4) a method of drug discovery and development using pattern-matching of previous drugs based on pharmacogenomic phenotype population clusters, and (5) a method to build an optimal pharmacogenomics knowledge base through derivatives of private databases contained in pharmaceutical companies, biotechnology companies and academic research centers without the risk of exposing raw data contained in such databases. Embodiments include pharmacogenomic decision support for an individual patient in an inpatient setting, and optimization of clinical cohorts based on pharmacogenomic phenotype for clinical trials in drug development.

The invention discloses two lactobacillus separation strains with anti-inflammatory activity and beneficial properties, which are Lactobacillus sakei GMNL-76 and Lactobacillus reuteri GMNL-89. The two lactobacillus separation strains are respectively preserved in the Bioresouce Collection and Research Center (BCRC) of the Food Industry Research and Development Institute (FIRDI) by preservation numbers of BCRC 910355 and BCRC 910340 and preserved in the China Center for Type Culture Collection (CCTCC) by the preservation numbers of CCTCC M 207153 and CCTCC M 207154. The two lactobacillus separation strains and subculture offspring thereof can be used for preparing various food products and pharmaceutical composition for curing and / or mitigating diseases (such as rheumatoid arthritis) relevant to inflammation.

The invention discloses two Lactobacillus isolated strains with anti-inflammatory activity and beneficial probiotic characteristics, namely lactobacillus sakei GMNL-76 and Lactobacillus reuteri GMNL-89, which are respectively preserved at the Bioresource Collection and Research Center (BCRC) of the Food Industry Research and Development Institute (FIRDI) with the preservation numbers of BCRC 910355 and BCRC 910340, and preserved at the China Center for Type Culture Collection (CCTCC) with the preservation numbers of CCTCC M 207153 and CCTCC M 207154. The two Lactobacillus isolated strains and subculture progeny thereof can be used for preparing various food products, and drug composites used for curing and / or relieving diseases related to inflammation, such as rheumatoid arthritis.

The invention discloses an agricultural pest and growth condition forecasting, prevention and control Internet of things, which consists of an agricultural pest and growth condition information acquirer, an information transmission network and an agricultural pest and growth condition forecasting, prevention, control and research center. In an agricultural pest and growth condition forecasting, prevention and control method, a method for acquiring comprehensive agricultural pest and growth condition information, software for processing the comprehensive information and a forecasting, prevention and control expert system database are provided. The agricultural pest and growth condition forecasting, prevention and control Internet of things is constructed creatively; a high-efficiency, high-quality and standardized informationization platform is supplied to develop deep research on various agricultural, forestal, animal husbandry and fishery pests and growth conditions in a large area, and agricultural informationization can be realized really in a large area, so that pests can be prevented and controlled designedly and timely step by step; furthermore, agricultural planting is instructed, and fertilizers are used rationally; therefore, pollution to the environment is reduced greatly, the insecticide resistance of the pests is reduced, and the agriculturally sustainable development is promoted greatly.

Disclosed are a system and a method for analyzing and utilizing intellectual property information. The method comprises the steps of registering search strategy formulas for extracting intellectual property (IP) information; accessing and searching Internet websites that provide IP information based on the registered search strategy formulas, and extracting first IP information according to the search; placing the first IP information in a standard form and performing a first storage operation of the first IP information, and transmitting the converted IP information to research center PCs; determining whether a request for detailed information has been made from the research center PCs, and if it has, accessing the Internet websites and extracting second IP information corresponding to the first IP information; and placing the second IP information in a standard form and performing a second storage operation of the converted IP information, and transmitting the converted IP information to the research center PCs. The system comprises an IP information extraction unit for extracting IP information according to the operation of software from at least one on-line IP information DB; an IP information analyzing unit for controlling the operation of the software, receiving the extracted IP information and storing the same together with data containing predetermined opinion contents, and outputting the IP information; and an E-mail receiving / transmitting unit for transmitting the IP information received from the IP information analyzing unit to research center PCs, and receiving feedback of data containing opinion contents from the research center PCs.

The invention discloses a coated carrier and the application thereof in the method for detecting maturity of sperms and separating mature sperms noninvasively; the coated carrier is a carrier coated by hyaluronic acid, or hyalurate or hyaluronic acid derivatives; the detecting method is as follows: preparing specimens; loading the specimens to the coated carrier and covering with microscopic glass; reacting for 5-60 minutes at room temperature; observing by a microscope and counting; and calculating the combination ratio of hyaluronic acid of active sperms. The separating method is as follows: preparing specimens; loading the specimens to the coated carrier, reacting for 5-120 minutes at the temperature of 18-37 DEG C; and collecting the combined sperms. The coated carrier has the advantages of precise and reliable results, simple and fast operation, low cost and good safety performance, and can be used for estimating sperms quality, sperms maturity and analysis of the causes of sterility disease of mails, and is applicable to assisting reproduction or reproduction research center to safely collect mature and active sperms, so that the goal of improving embryo quality greatly is achieved.

There are provided medical data providing system and method which separate ID (identification) data and non-ID data of a patient to provide only medical data of the patient. The system is comprised an ID information storage unit, an non-ID information storage unit, a medical care code generating unit, a care database and medical care code list database. To epidemiological research, the system is connected to the hospital or research center. When the medical data of a patient are intended to use for medical researches, only the non-ID data are provided to the hospital side in a state where the ID data of the patient exist only in the patient terminal physically separated from a computer system of a hospital, so that it is possible to prevent the personal information of the patient from being leaked.

The invention discloses a Aquamicrobium defluvii and application thereof in removing sulfur-containing odorants. The Aquamicrobium defluvii SU1 disclosed by the invention is an isolate obtained by treating a reactor containing H2S and other odorants in Water Pollution Control Laboratory in Research Center for Eco-Environmental Sciences of Chinese Academy of Sciences; and the strain is collected in China General Microbiological Culture Collection Center, and the collection number is CGMCC No. 7399. The strain can be prepared into a microbial active filler for purifying sulfur-containing odorant gases, thereby solving the problem of odor pollution generated in the process of sewage or sludge treatment, refuse treatment, composting and the like. The degradation efficiency for sulfur-containing odorants, such as hydrogen sulfide, methyl mercaptan, dimethyl sulfide and the like, can reach higher than 83%.

The invention discloses a central stochastic system applied to a medical clinical test, belonging to the field of computer data processing. The system comprises a test management unit, a testee grouping unit and a trial medicine distribution unit. The competitive grouping of testees is realized, so the grouping process of the medical clinical test can be acknowledged and controlled in time and the period of the medical clinical test is ensured. In addition, every time a testee is visited, medicines are distributed to the testee according to the process of the test and a required medicine dose, thereby reducing the medicine waste and saving the cost. Furthermore, the trial medicines can be periodically produced and led in according to the stock conditions of various research centers and the requirement conditions along with the practical process of the test, thereby greatly reducing the waste of overdue medicines, greatly improving the efficiency of the medicine replenishment and replenishing the medicines more promptly.

The invention relates to a medical resource sharing system based on a mobile internet. The system comprises a data center, a medical resource integration center, a self-diagnosis platform, a process customization platform, a remote consultation platform and a disease research center. By establishing an informatization platform and an integrated data warehouse, and by means of a big data analysis method, the management and decision-making levels of medical institutions are significantly improved, resource allocation and personnel allocation management are optimized, and business processes are simplified. A series of problems such as insufficient supply of medical resources, unequal information between patients and hospitals, low resource utilization rate, backward information construction and weak decision support information can be effectively solved, and convenience is brought to hospitals, doctors and patients.

The invention discloses a method, a device and a system for testees to randomly group in a medical clinical test, belonging to the field of computer data processing. The method comprises the following steps: generating a corresponding relation between random numbers and group numbers; assigning a random number for a testee applying a group when receiving a grouping application of the testee; obtaining the group number corresponding to the random number which is assigned to the testee applying the group according to the corresponding relation between random numbers and group numbers and recording the corresponding relation between the testee applying the group and the group number. The device comprises a corresponding relation generating module, a random number assigning module and a group number recording module. The system comprises a research center terminal device and a testee randomly grouping device in the medical clinical test. The invention realizes the competitive grouping of testees so as to acknowledge and control the grouping process of the test in time and ensure the period of the test.

The invention relates to a risk monitoring method and a system for quality supervision of a clinical trial research center, and the method comprises the following steps: providing an index configuration setting page, and receiving a first input of a normal value range and a weight of a risk index on the index configuration setting page; providing a docking configuration page, and selecting a clinical test research center to be subjected to quality supervision on the docking configuration page; acquiring data related to the risk indexes from the selected clinical test research center; calculating the risk index according to the data; dividing the risk indexes into a plurality of risk files according to the risk degree; and providing a result display page, simultaneously displaying a plurality of risk indexes of the plurality of clinical trial research centers on the result display page, and representing different risk files by using different colors. According to the method, quality supervision and risk monitoring can be timely and accurately carried out on a clinical test research center.

The invention provides a method for establishing a xenogeneic graft-versus-host disease model for NOD / SCID (non-obese diabetic / severe combined immunodeficient) mice, which includes: preparing active human PBMCs (peripheral blood mononuclear cells), establishing a model of NOD / SCID mice, detecting number and content of mouse-to-human white blood cells in implantation, and establishing pathologicalmanifestations of a mouse GVHD (graft-versus-host disease) target organ. Application of cyclophosphamide with anti-mouse CD122 (IL-2R beta chain) monoclonal antibody to pretreatment is used to substitute the sublethal dose irradiation process to establish the humanized GVHD model for NOD / SCID mice. The model is capable of simulating characteristics of graft-versus-host diseases after allogeneic hematopoietic stem cell transplantation in clinical chemotherapeutic pretreatment, and is high in establishing efficiency and high in repeatability. The model establishment process is simple and easy. The shortage that domestic research centers lacking relevant irradiation equipment fail to carry out relevant researches is overcome, and an experimental platform for human immune system GVHD researchon live animals can be provided.

A market research management and optimization system includes a plurality of geographically dispersed market research centers and a centralized computer management system, accessible via a single client interface, for coordinating the plurality of geographically dispersed market research centers and human capital requirements in order to conduct research exercises in the market research centers. The centralized computer management system includes a database for storing facility information for the geographically dispersed market research centers, and human capital data associated with research participants. A scheduling engine is used to reserve and coordinate the research exercises in the geographically dispersed market research centers, and for reserving and coordinating lodging requirements for research exercise participants. An optimization system communicates with the database and scheduling engine for selecting one or more of the geographically dispersed market research centers and a subset of research volunteers based on criteria provided by a corporate research sponsor. A centralized payment processing system facilitates financial transactions and settlements associated with the scheduling engine.

The invention discloses ochrobactrum anthropi SL1 and application thereof to removal of repugnant substances containing sulfur. Ochrobactrum anthropi SL1 is an isolate obtained from a reactor for treating repugnant substances containing H2S and the like in a water pollution control laboratory in Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. The strain is collected in China General Microbiological Culture Collection Center (CGMCC), with collection number of CGMCC No.7400. The strain can be used for preparing microbial active fillers, is used for purifying the repugnant substances containing sulfur and solving the problem of odor pollution produced in the processes of sewage, sludge and refuse treatment and composting, and has more than 90% of efficiency of degrading repugnant substances containing sulfur such as hydrogen sulfide, methanethiol, dimethyl sulfide and the like.

There are provided medical data providing system and method which separate ID (identification) data and non-ID data of a patient to provide only medical data of the patient. The system is comprised an ID information storage unit, an non-ID information storage unit, a medical care code generating unit, a care database and medical care code list database. To epidemiological research, the system is connected to the hospital or research center. When the medical data of a patient are intended to use for medical researches, only the non-ID data are provided to the hospital side in a state where the ID data of the patient exist only in the patient terminal physically separated from a computer system of a hospital, so that it is possible to prevent the personal information of the patient from being leaked.

The invention provides a test consumable automatic stock replenishment method which is applied to a research center. The method comprises the steps that the current stock E of a test consumable within the research center and the historical data of using the test consumable are acquired; according to a preset stock replenishment forecasting period T, the estimated total number of exfoliation L in the stock replenishment forecasting period T is calculated; according to the preset number N of test consumables used by subjects in each interview and the interview period P of the subjects, the number S of the interviews of enrolled subjects in the stock replenishment forecasting period, the number U of the interviews of to-be-enrolled subjects in the stock replenishment forecasting period, and the total number R of used test consumables are calculated; the number Q of replenishment test consumables in the stock replenishment forecasting period is calculated, and then a stock replenishment request is sent to a warehouse; and the warehouse replenishes test consumables for the research center. According to the invention, the method can adaptively replenish the stock of the test consumables, and automatically ensures that the stock of the test consumables is sufficient but not wasted.

The invention provides an investigational drug inventory management system applied to research centers, the system comprising a processor and a computer readable storage medium. The system can implement the following steps: judging whether current inventories E of various investigational drugs in a research center are all greater than or equal to a preset safe inventory V of the research center in real time; if not, obtaining the current inventory E and historical data of use of each investigational drug in the research center, and calculating the predicted total number L of dropout people in a prediction period T according to the preset warehouse prediction period T; according to the number N of drugs a preset subject takes upon each visit and a subject visit period of P weeks, calculating the number S of visits in the prediction period of enrolled subjects, the number U of visits in the prediction period of to-be-enrolled subjects and the total number R of drugs to be taken; calculating the drug supply quantity Q in the prediction period; generating a drug transport list according to which warehouses supplement the inventories of the investigational drugs for the research center.

The invention discloses two Lactobacillus isolated strains with anti-inflammatory activity and beneficial probiotic characteristics, namely lactobacillus sakei GMNL-76 and Lactobacillus reuteri GMNL-89, which are respectively preserved at the Bioresource Collection and Research Center (BCRC) of the Food Industry Research and Development Institute (FIRDI) with the preservation numbers of BCRC 910355 and BCRC 910340, and preserved at the China Center for Type Culture Collection (CCTCC) with the preservation numbers of CCTCC M 207153 and CCTCC M 207154. The two Lactobacillus isolated strains andsubculture progeny thereof can be used for preparing various food products, and drug composites used for curing and / or relieving diseases related to inflammation, such as rheumatoid arthritis.

The invention relates to a feed, and particularly relates to a biological feed capable of reducing cholesterol and increasing protein. The feed is prepared from Juncao and fungus chaff by adding yeast and stacking and fermenting, wherein the Juncao is a new variety of Juncao cultivated in the National Research Center of Juncao, and the fresh Juncao has a high content of protein. In the biological feed, since the raw materials are fermented by use of high-activity yeast, the yeast is massively multiplied in the feed, and more yeast is further produced at an extremely high speed. A great amount of feed is converted into organic yeast ingredients, the enzyme of the yeast strain promotes the digestive absorption of an animal, and an aim of saving feed and reducing cost is achieved; by feeding the livestock / poultry with the feed, the epidemic diseases are reduced, the immunity is enhanced, and the survival rate is improved; an obvious effect is realized after two-week feeding, for example, the fur is bright, the health status is obviously improved, the livestock / poultry likes sports, the growth speed is obviously increased, stink of the livestock / poultry house is avoided, and the feeding environment is effectively improved.

The invention relates to a sterile line selective-breeding and hybrid breeding method of pest-resistant and low-gossypol natural colored cotton. The sterile line selective-breeding and hybrid breeding method is characterized in that low-gossypol Shandong cotton-12 as a female parent and pest-resistant Shandong cotton research center (SCRC)-21 as a male parent are subjected to hybridization matching, and in the F2 generation group, plants of which cotyledons, stems and leaves do not contain gossypol are selected and a low-gossypol cotton line 8HN538 is obtained after continuous selfing plantation of the plants for 3-4 generations; a pest-resistant genic male sterile line variety Shandong RH-1 as a female parent and a nut-brown low-gossypol natural colored cotton parent 00S17 as a male parent are subjected to hybridization matching, pest-resistant plants in the F2 generation group are retained, and male fertile low-gossypol cotton plants are selected and are used for pollination on low-gossypol cotton male sterile plants; nut-brown cotton offspring is selected and retained; a continuous selective-hybridization process is carried out until the 4th generation so that a pest-resistant low-gossypol natural colored cotton genic male sterile line 0-173-3A is obtained; and the low-gossypol cotton line 8HN538 having pest resistance as a male parent and the pest-resistant low-gossypol natural colored cotton genic male sterile line 0-173-3A as a female parent are subjected to hybridization matching plantation so that the pest-resistant and low-gossypol natural colored cotton hybrid is obtained. The pest-resistant and low-gossypol natural colored cotton hybrid has a high yield, good fiber quality and a stable and uniform color, does not contain gossypol in cotton seeds, and greatly improves a comprehensive utilization value.

The invention discloses an early-maturing high-ginning-outturn cotton line breeding method which comprises the steps: A, utilizing early-maturing gene resources to breed an early-maturing novel material in a growth period: performing middle 5168 parent selection of an early-maturing variety; B, increasing spacetime selection pressure and breeding a very early-maturing cotton novel material with high pre-frost yield, high yield and stable yield; 1) increasing time selection pressure; 2) increasing space selection pressure; C, a breeding method in which low-generation mixed selection, high-generation single selection and Hainan island progeny planting are combined: 1) performing low-generation mixed selection; 2) performing high-generation single selection; D, a molecular marker screening method of middle 5168: utilizing identified SSR markers of HAU3318, MGHES-73 and NAU3913 related to early-maturing characters to distinguish the middle 5168 from short season cotton varieties like middle 425, China cotton research institute 16, China cotton research institute 36 and China cotton research institute 74 and spring cotton varieties like deltapine cotton 15, Shandong research center 28,China cotton research institute 12, China cotton research institute 41, China cotton research institute 45 and Shandong cotton research center 1. The method has the advantages of easiness, practicability, convenience in operation, quick selection speed and high selection efficiency; the selected novel variety has the characteristics of early maturity and high ginning outturn.

The invention discloses a triene mycin compound, a preparation method and application thereof in treating prostatic cancer, particularly relates to four triene mycin compounds, a preparation method and active application thereof in resisting cells PC-3 of prostatic cancers, and discloses a chemical structural formula, physical and chemical properties and corresponding nuclear magnetism data of the compounds. The compound is separated from fermenting liquid of streptomyces cacaoi subsp.asoensis separated from moss soil of north slope of Taibai Mountain at main peak of Qinling; the strain is separated and identified by the Xuhongquan topic group of Resource and Environment Institute of Northwest Agriculture and Forestry University, the number of GenBank is KF620296, the number of strain is H2S5, the strain is collected into the Natural Medicine Chemical Study Center of Chemical and Medicine Institute of Northwest Agriculture and Forestry University, and the collection number is No.CA20151025.

The invention discloses a modular configuration structure of a research and development institution building. The research and development institution building is a three-layer structure which is in a Chinese character hui shape; three function areas and a corridor which is in a Chinese character hui shape are arranged inside the research and development institution building; the three function areas comprise an experimental area (1), a detection area (2) and a scientific and technical information area (3); the experimental area (1) is provided with small-sized testing equipment needed by researches of technological processes, technological conditions and relative productions; the detection area (2) is provided with detection equipment; the scientific and technical information area (3) is provided with a scientific and technical information center, a technical research center and a multimedia conference room; the internal side of the corridor (4) which is in the Chinese character hui shape is a courtyard (5); the external side of the corridor which is in the Chinese character hui shape are the function areas; a rear portion of an external wall on a non-front surface of the main building is externally provided a distribution room and a fire protection control room (6) in a hanging mode; the experimental area (1), the detection area (2) and the scientific and technical information area (3) are provided with subsidiary rooms (7); and the subsidiary rooms comprise rest areas, washrooms, conference rooms, staircases, storehouses, dedusting machine rooms and the like.

The invention discloses formaldehyde-scavenging wallpaper and a production method thereof and belongs to the technical field of decoration materials. The formaldehyde-scavenging wallpaper comprises a bottom layer (1), a decoration layer (2) and an absorbing layer (3) from bottom to top and is formed by means of printing and stacking layer upon layer by a multicolour press, wherein the bottom layer (1) is non-woven fabric, the decoration layer (2) is a multicolor printing layer, and the absorbing layer (3) is made of materials with a formaldehyde adsorbing function. The formaldehyde-scavenging wallpaper has the advantages that the formaldehyde-scavenging wallpaper is capable of adsorbing and decomposing formaldehyde in the environment truly after being stuck on a wall, and recurrence is avoided; through testing of National Quality Supervision and Testing Center for Environment-Friendly products, formaldehyde scavenging ratio in 24 hours is 81%; through testing of (National) Technical Supervision and Research Center of the Building Materials Industry, the formaldehyde-scavenging wallpaper conforms to technical specifications of 'class-I materials' in JC / T1074-2008, and formaldehyde scavenging ratio is up to 80.6% (formaldehyde scavenging ratio is not less than 75% according to standard requirements of the class-I materials).

The invention discloses a method, a device and a system for distributing trial medicines in a medical clinical test, belonging to the field of computer data processing. The method comprises the following steps: generating the information of trial medicines for a testee according to the a test group corresponding to the random number of the testee when receiving a random number which is assigned to a testee and is submitted by a research center terminal device; obtaining the information of a required medicine dose and assigning medicines to the testee according to the information of the required medicine dose. The device comprises a trial medicine information generating module, an acquisition module and an assigning module. The system comprises the medical clinical test trial medicine distributing device and the research center terminal device. In the process of a clinical test, the medicines are distributed to testees according to the process of the test and the required medicine dose, thereby greatly reducing the medicine waste.

A new strain of Lactobacillus plantarum LP28, which has deposited at Bioresource Collection and Research Center of Taiwan with a deposited number of BCRC No. 910435, also at China General Microbiological Culture Collection Center (CGMCC), has a deposit number of CGMCC No. 3346. The Lactobacillus plantarum LP28 or its metabolic products are beneficial for allergy releasing, and therefore the Lactobacillus plantarum LP28 is well developed to be used in food products and medications for allergy therapy or hypersensitivity releasing.

The invention relates to a polymer emulsifier for resisting decomposition of biopesticides in an emulsion in water (EW), and application of the polymer emulsifier. The polymer emulsifier is any one ora composition of two of a polymer emulsifier N-300 or G-100A produced by Shantou Daqian High-tech Research Center Co.Ltd.. The invention further provides application of the polymer emulsifier for resisting decomposition of the biopesticides in the EW, and the EW containing the polymer emulsifier. The polymer emulsifier lowers high-temperature decomposition, strong light decomposition or ultraviolet light decomposition of the biopesticides in the EW; that the polymer emulsifier N-300 or G-100A can decrease the decomposition rate of the biopesticides in the EW is discovered by the invention, especially for the EW prepared from viral biopesticide, bacterial biopesticide, fungus biopesticide, microbial metabolite biopesticide and the plant extract biopesticide, and the emulsifier provided byinvention greatly decreases the decomposition rate.