The invention discloses a method for efficiently synthesising and extracting
anthocyanin in blueberry, and specifically discloses a synthesis and extraction preparation technology for blueberry
anthocyanin. The method comprises the following steps: culturing blueberry cells by high hydrostatic-pressure assisted microbial
fermentation, and extracting blueberry
anthocyanin by
ultrafiltration chromatography; breaking the
cell walls of blueberry fruits by virtue of a high hydrostatic-pressure assisted
microbial metabolite to adequately release anthocyanin; adding producing enzymes of L-
phenylalanine,
rhodotorula glutinis and the like to promote synthesis for precursors which are not converted to anthocyanin in blueberry into anthocyanin simultaneously; subjecting the
fermentation liquor to treatment of centrifuging,
ultrafiltration separation, chromatographic purification, vacuum freeze-
drying and the like to obtain anthocyanin with the purity of 99.31%, wherein the extraction amount of anthocyanin is increased by 15-30%. The method disclosed by the invention is simple to operate, clean and harmless in
generation process, low in cost, high in anthocyanin yield, high in purity, without the need of human intestinal microbial degradation, high in
medical treatment health value, suitable for large-scale production application, and extremely high in market prospect.