59 results about "Ethyl pyruvate" patented technology

The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof. The present invention further discloses a new process for the isolation and purification of racemic and optically active bicalutamide.

The invention relates to a method for synthesizing an organic compound. The method for synthesizing ethyl pyruvate adopts ethyl lactate and sodium hydroxide bicarbonate as raw materials, and the raw materials of ethyl lactate and sodium bicarbonate are prepared according to certain mole ratios and are processed by synthetic reaction in an organic solvent under the existence of an oxynitride catalyst and oxidizer trichloroisocyanuric acid; and after reaction, reaction liquid is processed by filtration, solvent removal, pressure reduction and distillation and then is collected to obtain the ethyl pyruvate product. Compared with the traditional method, the method for synthesizing the ethyl pyruvate is outstandingly characterized by reasonable proportion of reaction raw materials, simple and easily operated process, nearly 100 percent of percent conversion of the raw materials by particularly adopting the novel catalyst oxynitride and the oxidizer trichloroisocyanuric acid (TCCA), capability of quantitative reaction and high purity and yield of products obtained by reaction, thereby meeting the requirement of each industry on application.

The present invention provides methods for conferring cytoprotection and treating, suppressing or reducing the incidence of ischemia. The methods make use of an ester or amide of an alpha-ketoalkanoic acid, such as ethyl pyruvate, or compositions comprising the same.

The invention discloses a 4-halogenated-2-methyl-2-ethyl crotonate preparing method which includes following steps: (1) performing a Grignard reaction to ethyl pyruvate (II) and a vinyl magnesium halide Grignard reagent (III) to obtain a condensation compound (IV) after the reaction finished, and carrying out a hydrolysis reaction to the condensation compound (IV) to obtain a hydroxyl compound (V); and (2) performing a halogenating reaction to the hydroxyl compound and a haloid acid to obtain the 4-halogenated-2-methyl-2-ethyl crotonate (I). The 4-halogenated-2-methyl-2-ethyl crotonate preparing method is simple in total technology, allows raw materials to be obtained easily, is good in reaction selectivity, is less in by-products and is high in yield. The employed raw materials are all low-toxic or toxic-free and are all corrosiveness-free so that the method is not rigorous in requirement of devices, is environmental-friendly and is suitable for industrialized production.

The invention discloses a fresh flower preservative and a preparation method thereof. The fresh flower preservative is prepared from the following components in parts by weight: 70-80 parts of ethanol, 40-50 parts of ethyl pyruvate, 10-20 parts of citric acid, 8-15 parts of sodium citrate, 3-8 parts of sodium thiosulfate, 1-5 parts of stearic acid, 1-5 parts of salicylic acid, 0.5-2 parts of potassium sulphate, 1-5 parts of monopotassium phosphate, 5-10 parts of thiourea and 30-40 parts of water. The preparation method comprises the following steps: mixing ethanol and water, heating to 30-35 DEG C, adding with ethyl pyruvate, stirring for 10-20 min, then adding the other components, stirring for mixing uniformly, cooling to room temperature, and sealing for storage. With the fresh flower preservative, the flowering phase can be prolonged by 15-20 days on average, and meanwhile, fresh flowers with damaged branches, buds and leaves can bloom into bright flowers, so that the utilization ratio of the fresh flowers is greatly improved.

The invention relates to a method for synthesizing resorcinol by m-hydroxybenzoic acid. A one-step synthesis reaction is used, raw materials of m-hydroxybenzoic acid and a solvent are added in a high-pressure reaction vessel for being dissolved according to a mol ratio being 1-8:10-30, a catalyst is added for catalysis, the catalyst is a mixture of ethyl pyruvate and inulase, and m-hydroxybenzoicacid is obtained through steps of extraction and distillation. The reaction reduces soda acid pollution during a traditional technical production process and reduces the usage of a lot of organic solvents, which belongs to the environment friendly chemical reaction; waste water generated by post-treatment is less, and environment pollution is reduced.

The invention provides synergistic insecticide for oriental cherry trees, and a preparation method of the insecticide. The insecticide comprises an insecticide component and a synergistic component, wherein the insecticide component comprises carbamic acid ester, octachlorodipropyl ether, clove oil, acetamiprid, deltamethrin, chlorofluorocyantraniliprole, ethyl pyruvate, acetic anhydride and ethyl acetate; the synergistic component comprises castor oil, glyceryl oleate, emulsified silicone oil, 2-amino-2-methyl-1-propyl alcohol, ethyl acetate and ethanol. The preparation method comprises the following steps: preparing the insecticide component and the synergistic component respectively; mixing the insecticide component and the synergistic component to obtain the insecticide. The synergistic insecticide for the oriental cherry trees, provided by the invention, has significant prevention and control effects on aphides, red spiders and coccids on the oriental cherry trees, and does not influence the growth of shoots of the oriental cherry trees after being sprayed on the oriental cherry tree. The leaf color, the leaf quantity and the leaf quality of the oriental cherry trees which use the insecticide are obviously superior to those of the oriental cherry trees which do not use the insecticide.

The invention relates to a heterogeneous catalyst used in an asymmetric catalytic hydrogenation reaction of Alpha-keto ester, and the preparation as well as the application thereof, and belongs to the technology field of a chemical catalyst and synthesis. The expression of the catalyst is Pt/FDU-14; when in preparation, platinic chloride or Tetrammine platinum (2) Chloride is used as an active component precursor, and FDU-14 is used as a carrier; part of catalyst precursor is vacuum-roasted in a muffle furnace after insuccation and torrefaction, and finally the catalyst precursor is deoxygenized in sodium formate water solution to prepare the heterogeneous catalyst, wherein, the dispersion degree of active component platinum on the surface of the FDU-14 is 0.14 to 0.35, the loading of metallic platinum is 5.0 percent, and the mean particle size of platinum particles ranges from 3.2 to 8.0nm. When the heterogeneous catalyst is used in the asymmetric catalytic hydrogenation reaction of ethyl pyruvate under the room temperature and the medium hydrogen pressure, high activity and optical selectivity more than 70 percent are obtained in acetic acid solution, and the heterogeneous catalyst can be repeatedly used for more than 15 times.

The invention discloses a preparation method of a slow-release fertilizer for Brassica alboglabra. The preparation method includes: mixing organics, sodium bicarbonate, calcium carbonate, diatomite, and humic acid to obtain mixture I; adding corn meal, sucrose ester and a chemical fertilizer into the mixture I, stirring and mixing, adding ethyl pyruvate, stirring, and granulating to obtain a granulated fertilizer; drying the granulated fertilizer to obtain the slow-release fertilizer for Brassica alboglabra. The slow-release fertilizer for Brassica alboglabra prepared via the preparation method can continuously release fertility for long time and can increase the yield of Brassica alboglabra.

The invention relates to a solid waste treatment method of ethyl pyruvate, and the method comprises the following steps: mixing solid waste containing sodium isocyanurate for producing ethyl pyruvatewith tap water, performing dissolving, and keeping the temperature at 50-70 DEG C for 4-5 hours to obtain a first mixture; adding a sodium hypochlorite solid into the first solution, and performing stirring for 6-10 hours at 50-70 DEG C to obtain a second mixture; cooling the second mixture to room temperature, and keeping stirring for 1.5-2 hours to obtain a third mixture; carrying out centrifugal drying on the third mixture to obtain a first solid product and centrifugal mother liquor; and employing the first solid product for preparing ethyl pyruvate. According to the solid waste treatmentmethod of ethyl pyruvate, provided by the invention, the solid waste generated in the production of ethyl pyruvate is chlorinated and oxidized again to become a reaction raw material with a reaction effect again, almost no harmful effect is caused to the environment, and the solid waste can continuously participate in the circulation of synthesizing ethyl pyruvate after harmless treatment, so theproduction cost is greatly reduced.