32results about How to "Prevent and reduce injury" patented technology

Embodiments of the present disclosure include a user detection system for exercise equipment, such as a treadmill. In an embodiment, a sensor monitors displacement between a deck supporting a moveable treadmill belt and aspects of a treadmill frame. As users interact with the treadmill, a processor uses a sensor signal indicative of the displacement to determine whether a user has mounted the treadmill belt.

The present disclosure relates to an apparatus and a method for controlling a vehicle, which include a vehicle information acquisition module calculating a distance from a following vehicle and a relative speed of the following vehicle, if the following vehicle is detected on the rear side of a host vehicle based on detection information received from a detection module detecting an object around the host vehicle, a collision prediction module determining a probability of a potential collision of the following vehicle with the host vehicle based on the distance from the following vehicle and the relative speed of the following vehicle, and a controller accelerating or decelerating a traveling speed of the host vehicle, or adjusting brake torque of the host vehicle, if the potential collision of the following vehicle with the host vehicle is predicted. According to the apparatus and the method of the present disclosure, when a probability of a potential collision with the following vehicle is predicted, injuries to a driver and occupants can be prevented or reduced.

A microprocessor controlled system for ensuring the safe operation of an auxiliary device, such as a wheelchair lift used in conjunction with a vehicle. The microprocessor preferably allows operation of the lift device when one or more parameters are met. These parameters include the following: the vehicle is in “park”, the parking brake is engaged, the vehicle ignition is “on”, the lift power switch is “on”, and the lift door is open. The present invention does not allow the vehicle to be shifted out of park if the lift door is open and / or when the parking brake is “on”.

The present invention relates generally to the prevention and / or treatment of cardiac and stroke injury. In particular, the present invention provides compositions and methods for preventing and treating tissue injury in cardiac and stroke settings and injury due to ischemia / reperfusion, hypoxia, cardiotoxicity of certain therapeutic regimens, and other causes, by administering an agent that inhibits sphingosine-1-phosphate lyase (SPL) activity.

The present invention provides methods of reducing the cytotoxic effects of nitric oxide and sulfides comprising coadministering nitric oxide with sulfide. In addition, the present invention provides novel pharmaceutical compositions comprising both nitric oxide and sulfide. The methods and compositions of the present invention may be used in the treatment or prevention of a variety of diseases and disorders, and also in the prevention of cell or tissue damage, including that resulting from ischemi hypoxia.

A fall arrest system for a billboard is disclosed. The billboard may have horizontally extending ribs and vertically extending sprits. A first bracket and a second bracket, each having a horizontal portion and a vertical portion, are provided. The horizontal portion extends beyond the billboard. The vertical portion has channels for receiving the ribs therein. At least one mechanical fastener connects the brackets to the ribs. An arresting line extends from the first bracket to the second bracket.

The present invention provides methods for conferring cytoprotection and treating, suppressing or reducing the incidence of ischemia. The methods make use of an ester or amide of an alpha-ketoalkanoic acid, such as ethyl pyruvate, or compositions comprising the same.

The invention is related to methods of protecting, preventing and reducing intestinal injury in a human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation (HS / R) comprising administering heparin binding epidermal growth factor (HB-EGF). The invention is also related to methods of inhibiting deterioration of intestinal blood flow and methods of preserving and increasing intestinal blood flow by administering HB-EGF to a human subject. In addition, the methods of the invention should improve the clinical outcome of human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation.

A vehicular head and neck safety system for use by an occupant of a vehicle comprising a net sized to contain the occupant's head while the occupant is seated in a seat of a vehicle, wherein the net is secured behind a headrest of the seat using fasteners. During a rapid deceleration event, such as a frontal collision, the system limits the forward movement and downward rotation of the occupant's head to prevent or reduce injury.

A top guide having an extendable and retractable guide plate for engaging and aligning lengths of pipe over a pipe gripping device is described. The top guide employs a linear actuator such as a hydraulic cylinder to extend and retract the guide plate into and out of a protective housing. The guide plate has a bumper with a V-shaped Stu face for engaging and aligning a pipe segment upon extension of the guide plate. The guide plate has an adjustment mechanism to allow the position of the guide plate to be changed to accommodate pipe of varying diameters.

The invention is related to methods of protecting, preventing and reducing intestinal injury in a human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation (HS / R) comprising administering heparin binding epidermal growth factor (HB-EGF). The invention is also related to methods of inhibiting deterioration of intestinal blood flow and methods of preserving and increasing intestinal blood flow by administering HB-EGF to a human subject. In addition, the methods of the invention should improve the clinical outcome of human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation.

The present invention relates to CD44 binding molecules, preferably anti-CD44 antibodies, and their use in methods for the prevention or reduction of ischemia-reperfusion injury in e.g. solid organ transplantation or in patients in shock. The invention further relates to methods wherein levels of soluble CD44 are determined in e.g. serum or urine as a prognostic factor for the risk of organ rejection.

Provided herein are methods for prevention and treatment of ischemia-reperfusion (IR) injury in the cardiac myocytes of a subject, by administration to the subject, a compound of formula I, or a salt, solvate, or stereoisomer thereof, in a sufficient amount either prior to, or during and / or after an ischemic event to mitigate or prevent IR injury to the cardiac tissue. Pharmaceutical compositions including the compound of formula I, or a salt, solvate, or stereoisomer thereof, and / or at least one additional therapeutic agent, are also provided.

This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.

A set of panels for protecting livestock during transportation, for use in a lorry with a cage for carrying livestock having railings and a guillotine door, comprising: a plurality of fixed panels, and four mobile panels, wherein the fixed panels comprise one or more layers of flexible material and a backing plate made of rigid material, to be arranged forming a horizontal strip along the inner walls of the cage railings, and wherein the mobile panels comprise pivoting wings that can adopt a folded position and an unfolded position, and wherein said mobile panels are arranged at the sides of the guillotine door, two on the inside of the cage and two on the outside thereof.

A system and method for reducing and preventing head injuries using a combination of hardware and software. Elevated neck stiffness can be learned through the system, device, and the method described in the present invention by delivering and pairing a certain appropriate sensory cue (SnC) with a certain appropriate significance cue (SgC). the system, device, and method are used to generally facilitate and validate an increase in neck stiffness to prevent or reduce the likelihood of concussion upon impact. The system employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver visual, auditory, and other cues (somatosensory, vestibular, etc.) as SnC. The system also employs a combination of hardware and software, such as using modified virtual reality (VR) headsets (in both hardware and software), to deliver somatosensory, vestibular, visual, auditory, and other cues as SgC.

Neuroinflammation mediated by microglia and infiltrating peripheral immune cells is a major component of stroke pathophysiology. The calcium activated potassium channel KCa3.1 is expressed selectively in the injured CNS by microglia, and KCa3.1 function has been implicated in proinflammatory activation of microglia. KCa3.1 is further implicated in the pathophysiology of ischemia / reperfusion (stroke) related brain injury. Senicapoc, an investigational drug with a proven safety profile and shown to cross the blood-brain barrier, is a potent and selective KCa3.1 inhibitor that intervenes in the inflammation cascade that follows ischemia / reperfusion, and is a potential treatment for stroke.

The invention provides a vibrator assembly of a centering structure, which comprises a flat plate assembly and a heavy hammer assembly, a hammer body of the heavy hammer assembly is connected with the flat plate assembly through an elastic connecting piece, and the two ends of a piston rod of the heavy hammer assembly are fixedly connected with the flat plate assembly through end covers; the elastic connecting piece comprises a centering spring, a centering spring seat and a centering spring seat limiting seat, a centering spring mounting hole is formed in the hammer body, and the centering spring is in close fit with the centering spring mounting hole of the hammer body through tolerance fit. Due to the closed box type structural design, the vibrator assembly has high torsion resistance and sufficient rigidity, the overall performance of the vibrator assembly is more stable, meanwhile, space is saved, the length and width of the whole vehicle are greatly reduced, and the vibrator assembly is beneficial to exploration in cities and towns. The mechanical structure is more stable and firmer, and compared with an air bag, the wear resistance is longer, and the service life is longer.

A method and apparatus for servicing a pressurized system is described. A purge fitting can be used to vent the pressurized system. Venting can release a gas, such as air, from the system. The pressurized system can be a climate control system (e.g., an air conditioning or refrigeration system), a brake system, a hydraulic system, or a service device for servicing a climate control system. The purge fitting allows air that may be trapped in the pressurized system to be vented by depressing a purge actuator, such as a purge button attached to the fitting. The air can be vented from an opening adjacent to the actuator or other orifice. By purging air directly from the system, the amount of air introduced into the system during servicing can be minimized. The invention also features a coupling member that can be compact in size. The coupling member can include a self-sealing valve assembly that prevents opening the coupling member until a proper coupling interconnection with a system to be serviced has taken place. The purge fitting can be incorporated in the coupling member or other service device.

Neuroinflammation mediated by microglia and infiltrating peripheral immune cells is a major component of stroke pathophysiology. The calcium activated potassium channel KCa3.1 is expressed selectively in the injured CNS by microglia, and KCa3.1 function has been implicated in proinflammatory activation of microglia. KCa3.1 is further implicated in the pathophysiology of ischemia / reperfusion (stroke) related brain injury. Senicapoc, an investigational drug with a proven safety profile and shown to cross the blood-brain barrier, is a potent and selective KCa3.1 inhibitor that intervenes in the inflammation cascade that follows ischemia / reperfusion, and is a potential treatment for stroke.

An air bag device for a driver's seat may include a main-cushion unit provided on a steering wheel and having a front chamber that comes into contact with the steering wheel and a rear chamber that faces a driver, a sub-cushion unit communicating with the main-cushion unit and protruding outwards from the main-cushion unit, and a guide chamber located in the main-cushion unit to define a passage for guiding gas produced in an inflator to the sub-cushion unit.

The present invention relates generally to a hinge assembly and refrigerator having the same. More particularly, the present invention relates to a hinge assembly and refrigerator having the same, in which the thickness of the hinge assembly is increased in the up and down direction compared to the conventional hinge structure to significantly increase the resistance to a continuous load, whereby it is possible to guarantee a sealing force above a predetermined level even in long-term use of the refrigerator.

This invention relates to privacy screens, specifically, portable privacy screens with an integrated vertical height measuring tool. A portable lightweight privacy screen that can be conveniently carried and assembled and disassembled. The privacy module has one ruled segmented crown and one ruled segmented base which are identical and interchangeable with each other. They are each considered a single unit that is detachably connected together by a plurality of tubular couplers and bungee cord. The privacy module also has a plurality of ruled segmented supporting poles which are identical and interchangeable with each other. Each is considered a single unit that is detachably connected together by a plurality of tubular couplers and bungee cord. The present invention provides the collapsibility aspect by attaching bungee cord at two points on each of the separate units, giving the user the quick ease of assembling and disassembling of the structure. Further intent of the present invention is to increase the privacy area for the user, by providing a plurality of walls. The design of the present invention to provide privacy on a plurality of sides is also facilitated by an easily detachable fabric cover, interlaced with elastic from end to end, on top and bottom, which attaches and secures the fabric cover at a plurality of points by an elastic loop on the ends of the ruled segmented crown and ruled segmented base. The present invention also provides the option of attaching a plurality of privacy module together. The present invention also presents an integrated means of measuring a person's standing height by adding graduating marks to the segmented supporting poles, as well as to the segmented crown and the segmented base. Height indicator marks are placed on top of the ruled segmented crown in conjunction with the ruled segmented supporting poles, to align them with the vertically placed ruled auxiliary arm, for height extensions above 6-feet.