41 results about "Dermal collagen" patented technology

An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response. The method of the invention creates more normal dermal architectures in skin with limited depths of skin removal by the series of superficial treatments that may be comparable to the extent of neocollagenesis caused by a deep skin removal treatment (e.g., CO2 laser skin removal).

The present invention refers to a Laser therapy system and a method for skin treatment, comprising:a unit for dispensing a Photosensitizer containing agent;a first light source which generates at least one first light with a first wavelength;a second light source as a Laser light source which generates at least a second light with a second wavelength;an optical system which is connected to the first and to the second light source, comprising an electromechanical displacement device with an optical deflection and focusing system such that the first and second light gets focused and a respective focus point can be controllably positioned in the skin; anda control unit for controlling the electromechanical displacement device and the first and the second light source such that the respective light spot with a controlled energy and position in the skin is produced.

The invention relates to an application of flavonoid quercetin in inhibition of skin scar formation and skin fibration. The application verifies that quercetin has no toxicity to fibroblast, human dermal fibroblast I / III-type collagen mRNA expression and protein synthesis can be inhibited by inhibiting a TGF beta1 signal pathway in cells, fibroblast can be inhibited to myofibroblast differentiation, so that skin scar formation or dermal collagen deposition (fibration) can be inhibited, Animal in-vitro experiment confirms that quercetin is effected on mice skin, bleomycin-induced mice skin fibration and tension force-induced mice skin scar formation can be inhibited. Because that quercetin has the characteristics of small molecular weight, high lipid solubility and good transdermal absorption capability, the molecules can be used for preparing the medicine for resisting skin scar formation and skin fibration, and have wide application prospect in medical, shaping and cosmetic fields.

A method for non-surgical rejuvenation of facial skin to correct both Type 1 aging changes in the epidermis layer of the skin causing visual changes in the skin and Type 2 aging changes in the dermis layer of the skin causing damage to supportive elements of the skin. The method includes the steps of exfoliation of the facial skin, stimulation of new dermal collagen deposition, removal of at least one of pigment and superficial blood vessels, relaxation of facial expression muscles, filling of soft tissue defects including at least one of deep facial lines and contour deformities, and tightening of the facial skin, and the steps of the method are applied according to a selected one of a plurality of age determined regimens.

A method for non-surgical rejuvenation of facial skin to correct both Type 1 aging changes in the epidermis layer of the skin causing visual changes in the skin and Type 2 aging changes in the dermis layer of the skin causing damage to supportive elements of the skin. The method includes the steps of exfoliation of the facial skin, stimulation of new dermal collagen deposition, removal of at least one of pigment and superficial blood vessels, relaxation of facial expression muscles, filling of soft tissue defects including at least one of deep facial lines and contour deformities, and tightening of the facial skin, and the steps of the method are applied according to a selected one of a plurality of age determined regimens.

At present, the synthetic leathers are made of artificial fibers, and due to the performance difference between the artificial fibers and real leather collagen fibers, the performances of the artificial leathers are greatly different from the performances of the real leathers. The existing reclaimed leathers have harder handfeel and the environment is polluted in the production processes of the reclaimed leathers. The invention provides a method for producing an artificial leather base material by compounding collagen fibers by utilizing spun-laced water jetting. The method comprises the following steps: 1) firstly preparing the collagen fibers into a collagen fiber sheet for compounding by utilizing spun-laced water jetting; and 2) opening and entangling the collagen fiber sheet by utilizing spun-laced water jetting in a spun-laced nonwoven process, at the same time, compounding the collagen fiber sheet with an opened and carded synthetic fiber sheet, and after compounding, implanting the synthetic fibers in the collagen fibers so that the two different fiber sheets are firmly bonded as a whole. The method has the following beneficial effects: after undergoing the subsequent coating processing, the obtained base material has stronger leather feel and better simulation than the traditional synthetic leathers and softer handfeel than the reclaimed leathers; and the method is more environment-friendly than the traditional production methods of the reclaimed leathers.

The invention belongs to the field of dermatology, and in particular relates to a recombinant collagen product used for repairing skin ultraviolet damage. The invention provides a recombinant collagen, which has a good repair effect on the skin damaged by ultraviolet rays, has a good adhesion effect on fibroblasts, can promote the proliferation of skin fibroblasts, and has no effect on the skin. Stimulating effect, good safety; at the same time, the recombinant collagen can significantly improve the inflammatory symptoms after skin damage, maintain the moisture of the epidermis, induce the growth of skin epidermal cells, and help repair the collagen fibers of the dermis, repair the skin damaged by light, and can be used for Preparation of cosmetic or medical cosmetic products.

A method for non-surgical rejuvenation of facial skin to correct both Type 1 aging changes in the epidermis layer of the skin causing visual changes in the skin and Type 2 aging changes in the dermis layer of the skin causing damage to supportive elements of the skin. The method includes the steps of exfoliation of the facial skin, stimulation of new dermal collagen deposition, removal of at least one of pigment and superficial blood vessels, relaxation of facial expression muscles, filling of soft tissue defects including at least one of deep facial lines and contour deformities, and tightening of the facial skin, and the steps of the method are applied according to a selected one of a plurality of age determined regimens.

The invention discloses an oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane and a preparation method thereof. The oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane is characterized in that the preparation method comprises the steps: by applying an electrostatic spinning technology and using traceable purified porcine dermis as a raw material and hexafluoroisopropanol as a solvent, stirring at 4-10 DEG C until the mixture is transparent, formulating to obtain electrostatic spinning mother liquor with concentration of 0.5-10%, and directly spinning to obtain the porcine dermal collagen micro-nano fiber membrane; then performing graft modification on the porcine dermal collagen micro-nano fiber membrane by using oxidation chitosan, thereby finally obtaining the oxidation chitosan graft modified porcine dermal collagen micro-nano fiber membrane. A membrane material not only has good bio-compatibility, biodegradability and mechanical properties, but also has anti-oxidation effects, antibacterial activities, anti-inflammation / wound healing promotion effects, anti-cancer / anti-tumor effects and antiviral effects of chitosan, is significantly better than a collagen composite membrane material prepared by using collagen as the raw material, and can be widely applied to the preparation of biomedical materials such as hemostatic materials, tissue engineering scaffold materials, biological dressings and the like.

The invention discloses a dermal collagen fiber prepared from tanning chromium-containing subsidiary waste and a preparation method thereof. In the preparation method, the tanning chromium-containing subsidiary waste is used as a raw material, is subjected to processing of puffing, separating fibers, splitting fibers and carding and the like by a physical, chemical and biochemical combination method on the premise of ensuring unchanged good physical and mechanical conditions of collagen fibers, and is prepared into the dermal collagen fiber with good performance and wide application ranges. The dermal collagen fiber reaches the following technical indexes: (1) the outer surface is provided with light blue fiber materials and does not have visible impurities; (2) the moisture content is between 18 and 25 percent; (3) the linear density is between 1.2 and 2.0 dtex; (4) the fiber length is between 20 and 30mm; (5) the breaking strength is more than or equal to 3.5 cN / tex; (6) the elongation at break is between 10 and 30 percent; and (7) the moisture regain is between 6 and 10 percent. The dermal collagen fiber can be used as raw materials of high-simulation leather (automobile seat leather, furniture leather, instep leather, garment leather, shoe lining leather, belt leather, luggage leather and the like), natural leather base cloth, senior carpets, senior wall paper, dermal fiber bedding and the like.