The invention provides a
biological repair membrane and a preparation method thereof. In the prior art, the existing
biological repair membrane has the following disadvantages that the
mechanical strength is poor, the suture point has the
cerebrospinal fluid leakage risk, the tissue regeneration and repair promoting performance is weakened, the residual
toxicity exists after the degradation, the
biocompatibility is poor, and the adhesion between the
repair material and the
brain tissue is easily caused, and other complications are easily induced. According to the present invention, the animal-derived membrane tissue is subjected to
cell removing and
antigen removing, and a natural
polymer material
coating capable of being adsorbed and providing bleeding stopping effect is coated on the
treated animal-derived membrane tissue so as to solve the problems in the prior art; the method specifically comprises: pretreatment,
degreasing with an organic
reagent,
cell removing and
antigen removing with an alkali liquid,
coating preparation, vacuum compression and freeze-
drying, packaging, and sterilization so as to complete the preparation of the
biological repair membrane; and the biological repair membrane has advantages of bleeding stopping,
antibacterial property, adhesion, natural three-dimensional space structure retaining, good
mechanical property, good
biocompatibility, good tissue growth induction, degradation non-
toxicity, wide
raw material source, low price, and easy
mass-production.