Gel coating accessory capable of preventing brain surgery cerebrospinal fluid leakage

Abstract

The invention relates to a gel coating accessory capable of preventing brain surgery cerebrospinal fluid leakage, comprising a first fluid component in a first buffer solution which contains lysine, dimeric lysine or polylysine and has the pH value of 3-12 in a first container, a second fluid component of a second buffer solution with the pH value of 3-12 in a second container, a combined solid component which is composed of poly (trimethylene carbonate), polylactic acid, polyethylene glycol, polyethylene glycol polytomy isomer, polyurethane, gelatine, polyphosphate, polyglycolic acid and copolymer thereof and blend thereof in a third container as well as a coating tool. When the first fluid component, the second fluid component and the solid component are mixed, gel is formed, and the gel is directly coated onto the part used for preventing brain surgery cerebrospinal fluid leakage.

Description

technical field [0001] The invention relates to the field of medical instruments, in particular to a surgical kit for hemostasis and anti-seepage. technical background [0002] Surgical operations and trauma will form bloody wounds, during which a large amount of blood will be lost, and it is necessary to use hemostatic means in time. The use of biocompatible absorbable hemostatic materials to stop bleeding on bleeding wounds is a common means of hemostasis, and there is an urgent need for hemostasis in surgical hemostasis, trauma, first aid, and home self-help hemostasis. It can be seen that providing a safe, The importance of effective, easy-to-use, and low-cost hemostatic materials to human health. Cerebrospinal fluid leakage is one of the complications after brain surgery and spinal surgery. Continuous cerebrospinal fluid leakage will hinder the healing of the incision. If the treatment is not timely or handled properly, it may cause wound healing, wound infection, meni...

AI Technical Summary

Problems solved by technology

First of all, from the aspect of application, this hemostatic material is mainly limited to the hemostasis of skin or soft tissue wounds, and the hemostasis of tissues and organs in the deep part of the body cavity, especially the hemostasis under endoscopy (such as minimally invasive endoscopy, colonoscopy and laparoscopy). During operation) there is still lack of effective means; the second, from the preparation method, epichlorohydrin is a colorless oily liquid, toxic and anesthetic, so producing this product is unfavorable to the environment, and the production cost is also higher; the third, from In terms of hemostatic effect, because its water absorption is not strong enough, the water absorption rate is low, and the speed of water absorption is slow, the hemostatic effect is not ideal, especially for active bleeding. The viscosity of the gel is poor, so the clot formed after interacting with blood has poor adhesion to the tissue, and cannot effectively block the damaged tissue and blood vessels, thus affecting the effect of hemostasis; fifth, during active bleeding, The hemostatic powder is difficult to adhere to the bleeding site and is easily washed away by the blood flow. If the auxiliary material is pressed on the hemostatic powder, the auxiliary material is easily adhered by the blood clot, causing re-bleeding when the auxiliary material is uncovered

Therefore, it is not effective for active bleeding hemostasis

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