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62 results about "Bee Venoms" patented technology

Venoms obtained from Apis mellifera (honey bee) and related species. They contain various enzymes, polypeptide toxins, and other substances, some of which are allergenic or immunogenic or both. These venoms were formerly used in rheumatism to stimulate the pituitary-adrenal system.

Methods

InactiveUS20100166804A1Ameliorating side effectSevere reactionBiocideAllergen ingredientsMetaboliteProphylactic treatment
The present invention relates to methods of prophylactically treating, reducing, delaying or controlling severe allergic reaction, e.g., to food and / or hymenoptera allergen, e.g. peanut allergen or bee venom allergen, in patients at risk of systemic anaphylaxis, e.g., patients receiving allergen desensitization therapy, through the use of a mast cell stabilizer, e.g., ketotifen and / or its metabolites or derivatives in free or pharmaceutically acceptable acid addition salts thereof. The invention further provides methods to desensitize a patient to one or more allergens comprising administering (i) one or more allergen to induce tolerance and (ii) one or more mast cell stabilizers in free or pharmaceutically acceptable salt thereof.
Owner:MASTCELL PHARMA

Useful properties of a bee venom protein and gene encoding same

The invention provides a novel protein, PX3.101, which can be isolated from honey bee venom, antibodies against the polypeptide and nucleic acids encoding PX3.101 and fragments thereof. The invention also provides pharmaceutical compositions based upon PX3.101 polypeptide and methods for using same in the treatment of various diseases, including various inflammatory diseases such as rheumatoid arthritis.
Owner:PAN PACIFIC PHARMA

High-yield wasp greenhouse breeding method

The invention discloses a high-yield wasp greenhouse breeding method. The method includes that a nest box and a hanging bracket are arranged in a sealed greenhouse; well-bred same standard swarms are moved to the greenhouse, the swarms can be both 'scoliid' and 'gourd bees', 3-5 swarms for each greenhouse, temperature, humidity and light are controlled manually, sufficient baits, beverage and nesting materials are provided, wasps are bred in the greenhouse all manually, bee venom is collected through a bee venom collector, bee pupa nest cakes are selected and cut via broken nest shell holes in bee pupa harvest seasons, broken nest cake layers are plugged and fixedly connected, nest shells are restored and covered, the bee pupa nest cakes of each swarm can be cut interruptedly and repeatedly. The method is safe, high yield is achieved, various shortcomings of wild breeding of the wasps are overcome, and the method is practical.
Owner:龙陵县黄氏蜂业有限公司

Ventilating anti-puncturing type anti-bee coat for firefighter

The invention relates to a ventilating anti-puncturing type anti-bee coat for a firefighter, which comprises a hood, a coat main body, gloves and boots, wherein the anti-bee coat is wholly in white color; the outer layer of the hood is made of a material of the coat main body; a knob type tightness-adjusting head hoop is arranged in the hood; an anti-pricking gasket having a supporting function is arranged at the head top; a convex high-density fine metal wire net is arranged on a face part of the hood; during a wearing process, a goggle is built in, so as to prevent the spilling of bee venom, and the anti-bee coat is ventilating and comfortable to wear; the outer layer of the coat main body is made of a ventilating coating material with a high-strength flame-retarding three-proofing functions; the interiors of the front and rear shoulders, rear sleeve pieces, front leg pieces and buttocks are enhanced, so that the anti-puncturing property is enhanced; and the inner layer is made of a thick sandwich netted material, so that the anti-bee coat is anti-puncturing and has a better supporting ventilating function. The ventilating anti-puncturing type anti-bee coat for the firefighter is anti-puncturing, fitting and light, excellent in ventilating property and high in safety and comfort.
Owner:SHANGHAI FIRE RES INST OF MEM

Bee venom emplastrum and preparation technology thereof

The invention relates to a special emplastrum prepared by mixing far-infrared ceramic powder with traditional Chinese medicinal micro-powder, active carbon micro-powder and a medical pressure-sensitive adhesive, and concretely relates to a bee venom emplastrum for blood circulation invigorating, vein relaxing and pain relieving. The bee venom emplastrum has an obvious local microcirculation improvement function, and is suitable for pains in neck, shoulder, waist and legs, hyperosteogeny, intervertebral disc protrusion and other symptoms. The bee venom emplastrum comprises a lining material, an emplastrum medicine layer and an emplastrum surface covering. The lining material is a nonwoven fabric; the emplastrum medicine layer is formed by the far-infrared ceramic powder, the active carbon micro-powder, the traditional Chinese medicinal micro-powder and the medical pressure-sensitive adhesive; and the emplastrum surface covering is a release paper or a release film. The bee venom emplastrum is prepared through the steps of stirring and mixing the above components, coating, cutting and packaging. The bee venom emplastrum has the characteristics of fast effectiveness, low allergy rate, use convenience and the like.
Owner:凌中鑫

Physical therapy liquid for treating neck-shoulder and lumbocrural pains and preparation method thereof

The invention discloses a physical therapy liquid for treating neck-shoulder and lumbocrural pains and a preparation method thereof. The physical therapy liquid is prepared from bee venom, scorpion venom, centipede venom, flowers carthami, angelica sinensis, cortex acanthopanacis, radix clematidis, caulis spatholobi, achyranthes root, mint, borneol and the like. The invention discloses a preparation method of the physical therapy liquid for treating neck-shoulder and lumbocrural pains. The preparation method comprises the following steps: grinding flowers carthami, angelica sinensis, cortex acanthopanacis, radix clematidis, caulis spatholobi, achyranthes root and mint into ultrafine powder according to a specific ratio; soaking by alcohol to extract effective ingredients out of the Chinese herbal medicines; filtering out medicine liquid; adding bee venom, scorpion venom, centipede venom, borneol and laurocapam; evenly mixing, filtering, and finally subpackaging. The physical therapy liquid can be widely applied to all pains caused by rheumatism and cold, such as rheumatic arthritis, rheumatoid arthritis, hyperostosis, periarthritis of shoulder, ischioneuralgia, lumbocrural pains caused by gynaecology, gastroenteropathy, neck-shoulder and lumbocrural pains.
Owner:王学林

Preparation method of effective polypeptide components in Vespula insects, and medicinal uses of effective polypeptide components

The invention relates to a preparation method of effective polypeptide components in Vespula insects, and medicinal uses of the effective polypeptide components. The effective components are obtained through a step of dialyzing crude hornet venom through a 30KDa dialysis membrane, and a step of freeze-drying or reduced pressure concentration drying of the above obtained dialysis liquid. A series of pharmacodynamic experiments verify that the effective biotoxin polypeptide components and transdermal absorption preparations thereof can substantially control the cerebral thrombus, can recover the mobility of cerebral palsy animals, can mitigate the ischemic brain injury, have stronger pharmacodynamic performances than first-line medicines comprising plavix, Xingnaojing and the like, and can be expected to be used for preparing innovative biochemical medicines for preventing and treating cardiovascular and cerebrovascular diseases in order to prevent and treat ischemic cardiocardiovascular diseases, such as myocardial infarction, cardiovascular thrombus, cerebral thrombus, cerebral infarction, acute / chronic cerebral apoplexy, and sequelae caused by cerebral infarction injury, like lateral hemiplegia, hemidysesthesia, hemiopia, facial and lingual paralysis, aphasia and general paralysis.
Owner:DALI UNIV

Bee venom toothpaste and preparation method of bee venom toothpaste

ActiveCN113476375ARepair rednessFix bleedingCosmetic preparationsToilet preparationsFoaming agentToothpaste
The invention relates to the technical field of antibacterial toothpaste, and particularly discloses bee venom toothpaste and a preparation method of the bee venom toothpaste. The bee venom toothpaste is composed of the following components by mass percentage: 0.1%-15% of composite antibacterial peptide, 1%-10% of solubilizer, 10%-36% of humectant, 0.4%-2% of adhesive, 0.5%-5% of foaming agent, 15%-25% of water, 0.65%-4.2% of other auxiliaries and 5%-40% of friction agent; each mass percentage of the composite antibacterial peptide is prepared from the following components in percentage by mass: 1-3% of honeysuckle, 2-6% of dandelion, 10-15% of liquorice, 2-10% of honey, 0.01-0.1% of bee venom extract, 0-1% of grain insects and the balance of edible oil. The bee venom toothpaste prepared by the invention is good in antibacterial effect, safe in components, low in irritation and not easy to cause allergic reaction of a human body.
Owner:广东日和堂医药科技有限公司

External bee venom liniment

The invention discloses an external bee venom liniment, and belongs to the preparation and a method for an external Chinese medicinal herb preparation. The method comprises the following steps: smashing clove, safflower, frankincense, ningpo yam rhizome, common jasminorange leaf and twig, szechuan lovage rhizome, cinnamon and shichimi into fine powder; putting the fine powder and bee glue into a multi-functional automatic extractor; soaking the mixture by using 95 percent ethanol for 5 hours; performing automatic circulation and reflux extraction on the soaked mixture to obtain extract; vacuumizing and drying the extract and smashing the vacuumized and dried extract into fine powder; grinding borneol into fine powder; uniformly mixing the two fine powder and the bee venom; adding a solvent into the mixture, uniformly stirring and standing the mixture; and filtering the mixture to obtain a product. The liniment product prepared by scientific mixing has the effects of promoting blood circulation and removing blood stasis, expelling wind, removing dampness and dispersing cold, and reducing swelling and easing pain. The external bee venom liniment can be used for treating diseases, such as cervical and lumbar intervertebral disc protrusions caused by cold and damp stagnation and qi stagnation and blood stasis, herpes, partial edema pain and functional limitations and the like.
Owner:缪晓青

Parischnogaster spp vespo bee venom polypeptide effective part and preparation and medical application thereof

InactiveCN103638060AProlong breathing timeSignificant antithromboticNervous disorderAnthropod material medical ingredientsDialysis membranesDisease
The invention relates to a Parischnogaster spp vespo bee venom polypeptide effective part and preparation and medical application thereof. Specifically, the effective part is prepared by dialyzing in the Parischnogaster spp rough bee venom with a dialysis membrane with molecular weight cutoff of 25KDa, and drying the eluate by means of freeze drying or concentration under reduced pressure. By a series of pharmacodynamic experiments, the inventor verifies that the biotoxin polypeptide effective part and transdermal absorption preparation thereof have the effects of remarkably preventing and treating generation of cerebral thrombus, recovering capacity for action of animal with cerebral palsy and relieving ischemic brain injury, have stronger pharmacodynamic performance than the first-line medicines, such as plavix and Xingnaojing, can be expectedly used for preparing cardiovascular and cerebrovascular disease prevention and treatment biochemical drugs for preventing and treating ischemic cardiovascular and cerebrovascular diseases, such as myocardial infarction, cardiovascular thrombosis, cerebral thrombosis, cerebral infarction and acute / chronic cerebral apoplexy, and sequelae caused by cerebral infarction injury, such as hemiplegia, hemidysesthesia, hemianopsia, facial-tongue paralysis, aphasia and general paralysis.
Owner:DALI UNIV

Automatic control system for bee venom collector

The invention relates to an automatic control system for a bee venom collector. The automatic control system comprises a power supply, a singlechip control circuit and a pulse generation circuit, wherein the power supply is a direct current rechargeable storage battery or an external alternating current power supply; the singlechip control circuit is an automatic switching circuit controlled by a chip, controls a switch to be regularly switched, controls the power supply and the pulse generation circuit, automatically stops working when the voltage of the power supply is insufficient; and the pulse generation circuit generates electric pulses to stimulate the stinging of bees to discharge bee venom. The automatic control system has the advantages of low energy consumption, automatic control, convenience for operation and the like; and a bee venom collection circuit and a bee venom collection program can be automatically started on time to automatically collect the bee venom, so that labor intensity can be reduced.
Owner:SHANGHAI UNIV

Bee venom inflammation-diminishing gel toothpaste and preparation method thereof

The invention discloses bee venom inflammation-diminishing gel toothpaste. The bee venom inflammation-diminishing gel toothpaste comprises the following components in parts by weight: 230-300 parts ofwater, 260-340 parts of calcium carbonate, 210-260 parts of sorbitol, 45-58 parts of polyethylene glycol, 45-55 parts of hydrated silica, 25-36 parts of lauryl sodium sulfate, 5-10 parts of sodium carboxymethyl cellulose, 5-10 parts of calcium hydrophosphate, 4-10 parts of xanthan gum, 3-8 parts of sodium benzoate, 3-8 parts of titanium dioxide, 3-8 parts of a mint extract, 3-7 parts of a propolis extract, 0.2-0.6 part of bee venom, and 8-15 parts of basic salt. After the toothpaste is used, the toothpaste can refresh the oral cavity, remove pathogenic bacteria in the oral cavity, resist bacteria, diminish inflammation, has high cleaning power and reduce allergy, and active ingredients in the formula can well exert the efficacy.
Owner:广东人为峰健康管理科技有限公司

Bee venom permeating agent, preparation method thereof, preparation and application

The invention discloses a bee venom permeating agent, a preparation method of the bee venom permeating agent, a preparation and an application. Raw materials of the bee venom comprise alcohol, wasp bee venom powder, old working bee of live wasp and picadura. After the steps of the bee venom original fluid preparation, the worker bee material preparation, the mother liquid preparation and the preparation, the bee venom permeating agent is obtained. The bee venom permeating agent can be directly smeared on the pain areas caused by rheumatism, scapulohumeral periarthritis and arthritis. The bee venom permeating agent rapidly permeates through the histocyte, the blood capillary and other areas of the pain areas through the skin clearance. The effect is direct, the curative effect is rapid, and the efficacy of the bee venom especially the wasp bee venom is fully utilized. Accordingly, the current problems of the low efficacy of the wine steeping with the old worker bee and non-drinkers are thoroughly solved.
Owner:德宏职业学院

Bee venom-containing external liniment composition for dredging collateral, removing blood stasis, diminishing inflammation and easing pain

The invention provides a bee venom-containing external liniment composition for dredging collateral, removing blood stasis, diminishing inflammation and easing pain. The bee venom-containing externalliniment composition is composed of bee venom, royal jelly, honey, rose oil, litsea cubeba oil, oil-tea camellia oil, wintergreen oil, turpentine oil, white camphor oil, cinnamon leaf oil, cinnamaldehyde oil, soybean oil, safflower oil and clove oil. The bee venom-containing external liniment composition for dredging collateral, removing blood stasis, diminishing inflammation and easing pain can converge and tighten the skin, so that the skin is finer and softer. The bee venom-containing external liniment composition is used as massage oil and scraping oil for massaging or scraping related acupoints, and thereby bronchitis and asthma are effectively relieved. The effects of dredging collateral, removing blood stasis, diminishing inflammation and easing pain are achieved.
Owner:黔东南苗族侗族自治州农业科学院 +1

Ventilating anti-puncturing type anti-bee coat for firefighter

The invention relates to a ventilating anti-puncturing type anti-bee coat for a firefighter, which comprises a hood, a coat main body, gloves and boots, wherein the anti-bee coat is wholly in white color; the outer layer of the hood is made of a material of the coat main body; a knob type tightness-adjusting head hoop is arranged in the hood; an anti-pricking gasket having a supporting function is arranged at the head top; a convex high-density fine metal wire net is arranged on a face part of the hood; during a wearing process, a goggle is built in, so as to prevent the spilling of bee venom, and the anti-bee coat is ventilating and comfortable to wear; the outer layer of the coat main body is made of a ventilating coating material with a high-strength flame-retarding three-proofing functions; the interiors of the front and rear shoulders, rear sleeve pieces, front leg pieces and buttocks are enhanced, so that the anti-puncturing property is enhanced; and the inner layer is made of a thick sandwich netted material, so that the anti-bee coat is anti-puncturing and has a better supporting ventilating function. The ventilating anti-puncturing type anti-bee coat for the firefighter is anti-puncturing, fitting and light, excellent in ventilating property and high in safety and comfort.
Owner:SHANGHAI FIRE RES INST OF MEM

Bee venom acupoint plaster and preparation method thereof

The invention discloses a bee venom acupoint plaster which comprises a medicine application layer and a protective film. A base material is arranged between the medicine application layer and the protective film, and the base material comprises the following raw materials including, by weight, 0.07-10 parts of a pressure-sensitive adhesive, 0.07-12 parts of far infrared germanite powder, one permanent magnet and 0.01-70 parts of pharmaceutical composition; the pharmaceutical composition comprises bees, propolis, cantharides, huechys, camphor, scorpions, centipedes, frankincense, radix aconitipreparata, prepared monkshood mother roots, flos caryophylli, cudrania cochinchinensis, ephedra, radix angelicae, cortex cinnamomi, cassia twigs and bee venom. The plaster can be attached to differentacupoints, can promote blood circulation, promote menstruation, improve blood circulation, remove blood stasis and relieve pain, has a good curative effect on arthritis like rheumatoid arthritis andother diseases, avoids pains of live bee sting and toxic and side effects caused in the treatment process, and is simple and easy to use, safe and free of side effects.
Owner:SHIYAN SINOHIVE BIOTECH

Polypeptide valid target in Ropalidia fasciata insects and application thereof in preventing and treating cerebral thrombosis

The invention relates to a polypeptide valid target in Ropalidia fasciata insects and application thereof in preventing and treating cerebral thrombosis. The valid target is prepared by the following steps: dialyzing Ropalidia fasciata crude bee venom with a 30kDa dialysis membrane, and carrying out freeze-drying or vacuum concentration and drying on the dialysis solution. A series of pharmacodynamic experiments by people prove that the biotoxin polypeptide valid target and a transdermal absorption preparation thereof have obvious effects on preventing and treating cerebral thrombosis, restoring mobility of animals with cerebral palsy, preventing and treating platelet accumulation and relieving ischemic brain injury, and have better pharmacodynamic performance than Plavix, Xingnaojing injection and other first-tier medicines. The valid target is expected to be used for preparing innovative biochemical medicines for treating cardiovascular and cerebrovascular diseases and for preventing and treating ischemic cardiovascular and cerebrovascular diseases, such as myocardial infarction, cardiovascular thrombosis, cerebral thrombosis, cerebral infarction, acute / chronic cerebral apoplexy, and sequelae caused by cerebral infarction injury, including hemiplegia, hemidysesthesia, hemianopsia, facioplegia, paralysis lingualis, aphasia, pamplegia and the like.
Owner:DALI UNIV

Preparation method of effective polypeptide components in Polistidae insects, and medicinal uses of effective polypeptide components

The invention relates to a preparation method of effective polypeptide components in Polistidae insects, and medicinal uses of the effective polypeptide components. The effective components are obtained through a step of dialyzing crude hornet venom of Polistidae hornet through a 25KDa dialysis membrane, and a step of freeze-drying or reduced pressure concentration drying of the above obtained dialysis liquid. A series of pharmacodynamic experiments verify that the effective biotoxin polypeptide components and transdermal absorption preparations thereof can substantially control the cerebral thrombus, can recover the mobility of cerebral palsy animals, can mitigate the ischemic brain injury, have stronger pharmacodynamic performances than first-line medicines comprising plavix, Xingnaojing and the like, and can be expected to be used for preparing biochemical medicines for preventing and treating cardiovascular and cerebrovascular diseases in order to prevent and treat ischemic cardiocardiovascular diseases, such as myocardial infarction, cardiovascular thrombus, cerebral thrombus, cerebral infarction, acute / chronic cerebral apoplexy, and sequelae caused by cerebral infarction injury, like lateral hemiplegia, hemidysesthesia, hemiopia, facial and lingual paralysis, aphasia and general paralysis.
Owner:DALI UNIV

Apparatus for collecting bee poison

Disclosed herein is a bee venom collector device, comprising: a covering member (1); a frame (5) to which the covering member is attached, having wire guiding grooves 5 arranged at regular intervals in one side thereof; a control bar (2), having a plurality of wire grooves (2') formed at regular intervals thereon, combined with the frame (5) at a position opposite to the guiding grooves (5') in such a way that it is movable to modulate the tension of wires guided by the wire grooves; a pair of wires (3), each being connected to both a cathode and an anode supported and guided by the guiding grooves (2') and (5') formed respectively at the control bar (2) and the frame (5), repeatedly running therebetween on tracks arranged at regular intervals according to the grooves; a glass plate, fitted in the frame (5), for receiving the bee venom; ; a base plate (8) attached at the back of the glass plate (7) to protect the glass plate; a fixing member (9) for firmly fixing the glass plate (7) and the base plate (8) in an inner space (4) of the frame; a controller (11), electrically connected to the pair of the wires (3) supported by the frame (5), for freely controlling the supply time of currents and elevating an output voltage to a predetermined level; and a power supply (15) for supplying electrical power to the controller (11).
Owner:REPUBLIC OF KOREA (MANAGEMENT RURAL DEV ADMINISTRATION) +1

Bee venom peptide and separation and purification method thereof

The invention discloses melittin and a separation and purification method thereof, and relates to the technical field of biology. The method comprises the following steps: carrying out primary reversed-phase C18 semi-preparative column separation on a bee venom crude extract to be separated and purified, carrying out gradient elution by taking a formic acid aqueous solution and acetonitrile as mobile phases, collecting an eluent, then freeze-drying the eluent, redissolving, and carrying out secondary reversed-phase C18 semi-preparative column separation on the redissolved solution, in the secondary reversed-phase C18 semi-preparative column separation, a trifluoroacetic acid aqueous solution and methanol are used as mobile phases for isocratic elution. The method can achieve the technical effects of high separation purity, less target substance loss and less organic solvent dosage without combining with an ultrafiltration process for impurity removal in a specific pH environment, and has the technical advantages of environmental friendliness, simple device, simplicity and convenience in process operation and suitability for industrial production.
Owner:INST OF QUALITY STANDARD & TESTING TECH FOR AGRO PROD OF CAAS

Composite antibacterial peptide and preparation method thereof as well as bee venom conditioning ointment capable of rapidly relieving pain and preparation method of bee venom conditioning ointment

The invention discloses a composite antibacterial peptide and a preparation method thereof as well as a bee venom conditioning ointment capable of rapidly relieving pain and a preparation method of the bee venom conditioning ointment. The composite antibacterial peptide is prepared by adding a honeysuckle extract, a dandelion extract, a licorice extract, honey, a maggot extract and a bee venom extract into edible oil according to a ratio and decocting. The composite antibacterial peptide has the effects of rapidly relieving the pain, promoting tissue healing and being not prone to allergy. In order to make the composite antibacterial peptide better penetrate through the epidermis to permeate into a bone layer and be convenient to use, the composite antibacterial peptide is made into ointment, namely the bee venom conditioning ointment capable of rapidly relieving the pain, so that the composite antibacterial peptide more rapidly permeates into the skin and acts on a affected part, and a better permeation assisting effect is achieved. According to the preparation method of the bee venom conditioning ointment capable of rapidly relieving the pain, a water phase, an oil phase and a mixed phase are separately emulsified and homogenized, and materials can be prepared during production, so that the production period is greatly shortened, and high-efficiency industrial production can be promoted.
Owner:广东日和堂医药科技有限公司

Preparation of bee venom with allergenic components removed

ActiveUS20160151426A1React SafeMaximally reducing phospholipaseCosmetic preparationsHair cosmeticsPhospholipaseUltrafiltration
Disclosed is a method for manufacturing a separated and purified bee venom (separated PBV) not possessing allergy-triggering effects by reducing or eliminating allergy-inducing components contained in a bee venom via ultrafiltration, thereby producing a PVB with desirable pharmacological effects while fundamentally blocking allergies that may be induced by the same. The manufacturing method of the present invention includes a first step of preparing a purified bee venom powder; a second step of preparing a bee venom liquid by mixing the purified bee venom powder with distilled water; a third step of removing allergic ingredients contained in the bee venom liquid via ultrafiltration through a membrane having a cut-off size of 10 kDa; and a fourth step of obtaining a separated PBV with the allergenic components removed; wherein the distilled water to be mixed with the purified bee venom powder in the second step is used in the range of from 1000 mL to 1500 mL per 1 g of the purified bee venom powder, the allergenic components removed through the ultrafiltration membrane in the third step are phospholipase A2 and hyaluronidase, and the separated PBV obtained in the fourth step contains 4 wt % or higher of apamin, and 50 wt % or higher of melittin.
Owner:CHUNG JIN BIOTECH

External application for dispelling cold, eliminating dampness, promoting blood circulation and dredging collaterals

The invention relates to an external application for dispelling cold, eliminating dampness, promoting blood circulation and dredging collaterals. The external application is prepared from the following raw materials of, in parts by weight, 45-65 parts of beewax; 0.8 to 1.2 parts of bee venom; 4-6 parts of colla apis; 8-12 parts of radix rehmanniae recen; 8-12 parts of radix bupleuri; 8-12 parts of crocus sativus L.; 18-22 parts of artemisiae argyi folium; 14-16 parts of lamiophlomis rotata (benth.) kudo; 18-22 parts of dried zingiber officinale rosc.; 14-16 parts of phellodendron amurense rupr; And 14-16 parts of atractylodes lancea (thunb.) DC. The effective components of the external application are all natural products, the beewax, the bee venom and the colla apis, three treasures of bee are taken as main medicines, and Chinese herbal medicines including the radix rehmanniae recen, radix bupleuri, crocus sativus L., artemisiae argyi folium, lamiophlomis rotata (benth.) kudo, dried zingiber officinale rosc., phellodendron amurense rupr and atractylodes lancea (thunb.) DC are taken as auxiliary medicines, so that the external application plays a synergistic interaction role in clearing and activating the channels and collaterals and promoting blood circulation to remove blood stasis. The raw materials complement each other, clearing and activating the channels and collaterals are mainly used for improving the nervous system, promoting the blood circulation to remove the blood stasis is mainly used for improving the blood system, and the two effects promote each other. The application is used for health care and treatment of neck and shoulder stiffness and aching pain, waist soreness and bone pain.
Owner:蜂针堂蜂疗服务连云港有限公司

Preparation method and application of antibacterial beewax paste

The invention provides antibacterial beewax paste, and relates to the technical field of medicines. The antibacterial beeswax paste comprises 0.1%-10% of beeswax; 0.05%-5% of bee venom; 0.03%-5% of propolis; 60%-80% of vegetable oil; 0.1%-5% of paraffin; 0.001%-3% of radix rehmanniae; 0.001%-2.5% of radix bupleuri; 0.001%-1.5% of stigma croci; 0.001%-2% of Chinese prickly ash; 0.001%-4% of foliumartemisiae argyi; 0.001% to 1.5% of herba lamiophlomis; 0.001%-5% of rhizoma zingiberis; 0.001%-3% of cortex phellodendri; 0.001%-2% of rhizoma atractylodis; and 0.3%-0.5% of chlorhexidine acetate which is a broad-spectrum bacteriostatic agent. According to the antibacterial beewax paste, the effects of detoxifying the body, stopping bleeding and relieving pain by the beewax are utilized, the antibacterial and anti-inflammatory effects are improved, the use of an antibacterial agent by the antibacterial paste can be reduced, and the occurrence of allergy is reduced; the preparation process issimple, the cost is low, and the product stability is good; the physiological moist environment of the skin and the mucous membrane can be kept; due to the weak acidity characteristic of thevegetableoil, the weakly acidic environment of the skin and the mucous membrane can be maintained, and the wound surface is not irritated; the beewax has the effects of promoting tissue regeneration and stopping dysentery, and can promote wound surface healing; and therefore, the practicability of the antibacterial paste is improved.
Owner:阳光蜂慧(北京)蜜蜂医疗科学技术有限公司

Bee venom-purifying method comprising viral clearance process and composition for preventing or treating inflammatory disease by using same

The present invention relates to a bee venom-purifying method comprising a virus clearance process and a composition for preventing or treating inflammatory disease by using same, the method comprising the steps: (a) preparing a bee venom solution containing bee venom; (b) adjusting the pH of the bee venom solution prepared in step (a) into 2.0 to 4.0 by acid treatment to primarily deactivate viruses; and (c) filtering the pH-adjusted bee venom solution of step (b) through a nanofilter of 10-20 nm to secondarily remove viruses.
Owner:UBIO

Bee-venom nursing paste capable of dredging collaterals, relieving pain and diminishing inflammation

The invention discloses a bee-venom nursing paste capable of dredging collaterals, relieving pain and diminishing inflammation. The bee-venom nursing paste comprises, by mass percentage, 1-15% of propolis extract, 5-55% of ostrich oil, 1-10% of folium artemisiae argyi extract, 0.5-5% of panax notoginseng extract, 0.5-5% of ginger extract, 0.5-3% of sea-buckthorn extract and 0.1-2% of menthol. Thematerials above are used as the active components and coordinated with pharmaceutically acceptable auxiliary materials to prepare corresponding pharmaceutical preparations, especially all external-usemedicine dosage forms such as the external-use paste preparation. The paste is capable of fast diminishing swelling and relieving pain, has an evident synergistic effect, and is mild in property, safe, non-irritant and capable of treating both the symptoms and root causes of stubborn diseases. The preparation method of the paste is simple and easy to control and promising in application prospect.
Owner:广州人为峰昆虫产业研究院有限公司

Traditional Chinese medicine composition patch and preparation method thereof

The invention discloses a traditional Chinese medicine composition patch and a preparation method thereof. The traditional Chinese medicine composition patch comprises bee venom, propolis, dandelion, radix puerariae, ligusticum wallichii, radix clematidis, garden balsam stem, angelica sinensis, tripterygium wilfordii, dragon's blood, brassica juncea, cassia twig, corydalis tuber and caulis spatholobi. The bee venom, the eucommia ulmoides, the ligusticum wallichii and the salvia miltiorrhiza are used together, and the main effects of combating poison with poison, promoting blood circulation to remove blood stasis and dispelling wind and eliminating dampness are achieved. The traditional Chinese medicine patch has the advantages that the plaster is reasonable in formula, the effects of promoting menstruation and collateral dredging can be achieved, scapulohumeral periarthritis, cervical vertebra, waist and leg, sciatica and rheumatism can be treated, the semen brassicae junceae can play a role in heating without hurting the skin after being in contact with the skin; in addition, the propolis and the dandelion in the formula enable the patch to achieve the effects of diminishing inflammation and resisting allergy, and the problem that most people are allergic to the patch in the past is solved. Meanwhile, compared with a traditional 'black patch ', the medicine patch serving as an external application medicine patch can be torn down and then baked with fire, so that each medicine patch can be repeatedly used for 2-3 times.
Owner:北京至阳燎原中医技术研究院
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