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Bee venom permeating agent, preparation method thereof, preparation and application

A technology of penetrant and bee venom, which is applied in the field of bee venom penetrant and its preparation, to achieve the effects of weak efficacy, fast curative effect and direct effect

Active Publication Date: 2015-04-22
德宏职业学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no product that can give full play to its specific efficacy in the market, therefore, it is very necessary to develop a kind of above-mentioned product

Method used

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  • Bee venom permeating agent, preparation method thereof, preparation and application
  • Bee venom permeating agent, preparation method thereof, preparation and application
  • Bee venom permeating agent, preparation method thereof, preparation and application

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preparation example Construction

[0020] The preparation method of the bee venom penetrant of the present invention comprises the steps of preparation of bee venom stock solution, preparation of worker bee raw materials, preparation of mother liquor, and preparation steps, specifically comprising:

[0021] A. Preparation of bee venom stock solution: Add Vespa bee venom dry powder into alcohol according to the ratio, stir for 1-3 hours, seal and place in a light-proof environment at 2-8°C for 18-30 hours to obtain bee venom penetrant stock solution;

[0022] B. Raw material preparation of worker bees: Put the old and live wasps in the environment of 2-8°C for 5-10 minutes according to the ratio, and then transfer them to the container at 10-30°C after the live and old bees lose their flight and attack power. After 5-10 minutes to more than 90% of the live Vespa old mature worker bees recover their flying ability, the raw material of bee venom penetrant worker bee can be obtained;

[0023] C. Preparation of moth...

Embodiment 1

[0042]Step 1: Take 10,000ml of 75% alcohol and put it into the first 10,000ml (20kg) large glass wine bottle.

[0043] Step 2: Put 10 grams of pure dry powder of golden hornet bee venom into the alcohol of the first 10,000 ml large glass wine bottle, then stir well, seal it and place it in a dark environment at 18°C ​​for 18 hours to obtain Haomiao bee Toxic penetrant stock solution.

[0044] Step 3: Put 200, 400, and 1,200 golden hornet bees, yellow-waisted bees, and cucurbit bee workers that were taken from the wild forest at night and placed in a suction-type beehive cage, and put them into the freezer together with the beehives In an environment of 5°C for 10 minutes, after the standby bees lose their flight and attack power due to low temperature and inactivity, take out the cage, pour the worker bees into another 10,000ml large glass wine bottle with a tap, and seal the mouth of the bottle with gauze , the worker bees in the bottle gradually resume their activities at r...

Embodiment 2

[0050] Step 1: Take 10,000ml of 75% alcohol and put it into the first 10,000ml (20kg) large glass wine bottle.

[0051] Step 2: Put 10 grams of pure dry powder of golden hornet bee venom into the alcohol of the first 10,000 ml large glass wine bottle, then stir well, seal it and place it in a dark environment at 18°C ​​for 18 hours to obtain Haomiao bee Toxic penetrant stock solution.

[0052] Step 3: Put 500 golden hornets taken from the wild forest at night and put them in a suction-type beehive cage, and put them together with the beehives in the freezer at 5°C for 10 minutes. The standby bees will die due to low temperature and inactivity. After flying and attacking, take out the beehive cage, pour the worker bees inside into another 10,000 ml large glass wine bottle with a faucet, seal the bottle mouth with gauze, and the worker bees in the bottle will gradually resume their activities at room temperature for 10 minutes Finally, after more than 90% of the worker bees rec...

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Abstract

The invention discloses a bee venom permeating agent, a preparation method of the bee venom permeating agent, a preparation and an application. Raw materials of the bee venom comprise alcohol, wasp bee venom powder, old working bee of live wasp and picadura. After the steps of the bee venom original fluid preparation, the worker bee material preparation, the mother liquid preparation and the preparation, the bee venom permeating agent is obtained. The bee venom permeating agent can be directly smeared on the pain areas caused by rheumatism, scapulohumeral periarthritis and arthritis. The bee venom permeating agent rapidly permeates through the histocyte, the blood capillary and other areas of the pain areas through the skin clearance. The effect is direct, the curative effect is rapid, and the efficacy of the bee venom especially the wasp bee venom is fully utilized. Accordingly, the current problems of the low efficacy of the wine steeping with the old worker bee and non-drinkers are thoroughly solved.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a bee venom penetrant and its preparation method, preparation and application. Background technique [0002] Bee venom is a mixture of complex components, mainly including functional substances such as polypeptides, enzymes, and biogenic amines. Polypeptides are the main components of bee venom, accounting for about 75% of dry bee venom, including melittin, bee venom Melittin, MCD-peptide, Cardiopeptide, Sekajing, Tropeptide, Melittin F and Andura, etc. Melittin is the main component of bee venom, accounting for about 50% of dry bee venom. Melittin includes melittin I and melittin II. Melittin I is composed of 25 amino acids, and melittin II is composed of 27 amino acids. Melittin is another main polypeptide in bee venom, accounting for about 2% of the content of melittin. Consisting of 18 amino acids, MCD-peptide is the third major polypeptide substance in bee ve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K9/08A61K9/10A61K9/107A61K9/12A61K9/00A61P29/00A61P19/02
Inventor 郭云胶
Owner 德宏职业学院
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