Disclosed is a medicinal composition for treating schizophrenosis which is prepared from plaster stone, rhubarb horsetails, baikal skullcap root, corktree bark, celestite, goldthread root, curcuma aromatica, mirabilite, keel, hooked uncaria, cow-bezoar, mirabilite, natural indigo, grassleaved sweetflag rhizome, mentha, magnolia bark, aloe, bamboo leaves, spatholobus stem, boneol, magnolia bark, aloe, Chinese angelica root, banksia rose, rough gentian, immature bitter orange, green tangerine orange peel and riddle.