The invention discloses a large current measuring device with an anti-skin effect. The large current measuring device with the anti-skin effect comprises a coil mother plate, a positive electrode, a negative electrode, multi-split current conduits, and a signal acquisition and processing device; large current to be measured flowing through the positive electrode and the negative electrode is introduced into the multi-split current conduits and is split into multiple parts, each current conduit penetrates through the coil center on the coil mother plate to generate induced voltage, and a largecurrent value is obtained by measuring the superimposed induced voltage; the coil mother plate adopts an integrated forming technology, consistency of each coil is high, electromagnetic interference between adjacent coils is reduced, and accuracy of measurement results is improved; the current flowing through each current conduit is very small compared to total current, and the skin effect is effectively reduced; current directions of adjacent conduits are opposite, magnetic induction intensity around a conductor is weaken, and electric force between conductors is decreased; and multiple current conduits increase the heat dissipation area of the measuring device, and the problems that the measuring range is too narrow or the upper limit is difficult to be raised due to the heating effect of the current are solved.