The invention relates to a multi-source solid waste-based grouting cementing material as well as a preparation method and application thereof. The grouting cementing material is prepared from the following raw materials in parts by weight: 60 to 80 parts of red mud, 60 to 80 parts of other solid wastes, 40 to 60 parts of an excitant and 10 to 20 parts of an additive, wherein the other solid wastescomprise the following raw materials in parts by weight: 15-25 parts of furnace slag, 15-25 parts of mineral slag, 10-20 parts of steel slag and 8-20 parts of desulfurized gypsum. The preparation method is simple; the prepared grouting cementing material is short in setting time, high in early strength, high in stone body mechanical strength, excellent in erosion resistance and suitable for coastal karst broken rock mass reinforcement and treatment engineering, engineering safety construction in coastal areas can be guaranteed, the solid waste stockpiling pressure is relieved, the problem ofenvironmental pollution caused by red mud is solved, high added value is achieved, and comprehensive utilization of the red mud is promoted.