311results about How to "Low detection sensitivity" patented technology

The prostate gland or other region of interest is stimulated with laser light, resulting in ultrasound waves (photoacoustic effect) which are focused by an acoustic lens and captured by a specific 1- or 2D sensor array and subsequently displayed as a C-scan on a computer screen. The amplitude of the ultrasound waves generated by laser stimulation is proportional to the optical absorption of the tissue element at that spatial location. Variability in tissue absorption results in C-scan image contrast. The photoacoustic imaging is combined with an ultrasound C-scan image produced with a plane ultrasound wave applied to the region of interest.

Detection column wires and detection row wires are configured of thin wires made of a conductive material having light reflectivity, such as a metal or alloy including silver and aluminum. A predetermined plural number of detection column wires are electrically connected to form a plurality of column-direction bundle wires. A predetermined plural number of detection row wires are electrically connected to form a plurality of row-direction bundle wires. A reflected-light distribution pattern is further provided. When viewed in a direction vertical to the surface of the touch screen, the reflected-light distribution pattern includes a curved portion, and the normal lines of the curved portion head for all directions.

A cross point nonvolatile memory device capable of suppressing sneak-current-caused reduction in sensitivity of detection of a resistance value of a memory element is provided. The device includes perpendicular bit and word lines; a cross-point cell array including memory cells each having a resistance value reversibly changing between at least two resistance states according to electrical signals, arranged on cross-points of the word and bit lines; an offset detection cell array including an offset detection cell having a resistance higher than that of the memory cell in a high resistance state, the word lines being shared by the offset detection cell array; a read circuit (a sense amplifier) that determines a resistance state of a selected memory cell based on a current through the selected bit line; and a current source which supplies current to the offset detection cell array in a read operation period.

The invention provides methods for detecting contamination in a PCR reaction. Methods of the invention are especially useful for detection of contamination in heterogeneous samples containing a rare nucleic acid to be detected.

A water trap system based on a thermoelectric cooling device is employed to remove a major fraction of the water from air samples, prior to analysis of these samples for chemical composition, by a variety of analytical techniques where water vapor interferes with the measurement process. These analytical techniques include infrared spectroscopy, mass spectrometry, ion mobility spectrometry and gas chromatography. The thermoelectric system for trapping water present in air samples can substantially improve detection sensitivity in these analytical techniques when it is necessary to measure trace analytes with concentrations in the ppm (parts per million) or ppb (parts per billion) partial pressure range. The thermoelectric trap design is compact and amenable to use in a portable gas monitoring instrumentation.

The present invention relates to an apparatus for detecting one or more analytes, for example analytes selected from the group comprising nucleic acids, metabolites, peptides, proteins, hormones, pesticides, neurotransmitters, ions in blood, electrolytes, toxic gases, pH and biological warfare agents, the apparatus comprising an insulating substrate, at least one first electrode on the substrate at least one elongate nanostructure extending from and electrically connected to the or each said electrode and extending over the surface of the wafer away from the respective electrode, a passivating layer covering the or each electrode, but not all of said at least one elongate nanostructure, a well crossing the at least one elongate nanostructure extending from the or each electrode and forming a static reservoir for a liquid being investigated for the presence of at least one analyte, a reference electrode provided on said substrate within said well or insertable into said well and respective readout pads electrically connected to the or each electrode and to the reference electrode if the latter is provided on the substrate, the at least one elongate nanostructure being capable of being functionalized for detecting one or more analytes.

A vibrator for generating a signal for measuring a physical quantity using a vibrator is provided, including at least one bending vibration arm vibrating in bending mode along a specified plane and having a first end, an opposed second end, and first and second main faces that are substantially parallel with each other. A base portion is provided at the first provided at the first end of the bending vibration arm, a weight portion is provided at the second end of the bending vibration arm, and grooves are formed on the first and second main faces. The vibrator further includes driving means for exciting a driving vibration in the vibrator, and detecting means provided on one of the bending vibration arms for detecting an output signal based on detection vibrations induced in the vibrator responsive to the physical quantity to be measured.

The invention relates to a metal-modified photonic crystal biological detection film as well as a preparation method and application thereof. The film is a metal-modified photonic crystal film marked of a biological function substance which is marked by a fluorescence labeling molecule, wherein the biological function substance marked by the fluorescence labeling molecule is a biological function substance marked by a single fluorescence labeling molecule or a receptor fluorescence labeling pair. By the utilization of the characteristics of photonic crystal enhancement and metal surface enhancement, the adaptation of the fluorescence labeling biological function substance, and the specific responsiveness and the specific affinity of the fluorescence labeling biological function substance on a target biological substance, the target biological substance and the biological function substance generate response, thereby the illumination change of the biological function substance marked by the fluorescence labeling molecule is caused. Moreover, the sensitivity of a system for detecting the target biological substance can be effectively enhanced by reading and identifying fluorescent signals of the fluorescence labeling molecule through photonic crystal enhancement and metal surface enhancement, consequently the high-sensitivity biological detection can be realized.

A method, an apparatus and a computer program for determining a location at which satellite ranging signals (RS1-RS 4) have been received. At least one pseudorange selection cycle (511, 512), including an initial selection cycle (511), is performed and said location is determined utilizing the selected pseudoranges (1004). Said initial selection cycle includes: determining a first admissible pseudorange (r11) associated with a first satellite (SV1); determining (502) all pseudoranges (r21, r22, r31, r32) associated with at least two additional satellites (SV2, SV3) which combined with said first pseudorange (r11) form admissible relative pseudoranges; forming (503) a set (1001) of pseudorange vectors representing all possible combinations of said determined pseudoranges (r11, r21, r22, r31, r32) associated with said first (SV1) and at least two additional satellites (SV2, SV3); and forming (504) a set (1002) of selected pseudorange vectors by selecting at least one vector from said set (1001) of pseudorange vectors. At least when said set (1001) of pseudorange vectors includes plural vectors, said selecting includes evaluating each vector in said set (1001) of pseudorange vectors according to a predetermined rule.

Arrangement and method for the optical detection of light radiation which is excited and/or backscattered in a specimen, wherein the illumination of the specimen and/or the detection of the specimen light is carried out by at least two objectives arranged on different sides of the specimen. The specimen illumination is focused in or in the vicinity of a pupil plane of the beam path between the specimen plane and the detection plane at least on one axis and an element for the spatial separation of the illumination light from the detection light are provided in this plane.

A terahertz wave detection device which includes an absorption portion which absorbs a terahertz wave and generates heat and a conversion portion which converts the heat generated by the absorption portion into an electric signal, wherein the absorption portion includes a dielectric layer, a plurality of metal structures which are provided on one surface of the dielectric layer and are arranged to be separated from one another by an interval having a predetermined length; and a metal layer which is provided on the other surface of the dielectric layer, and wherein the interval is shorter than a wavelength of the terahertz wave which is absorbed by the absorption portion.

A mass spectrometer featured in including an ion source including a first electrode, a second electrode, and a dielectric unit having a sample introducing unit and a sample discharging unit and provided between the first electrode and the second electrode, a power source of ionizing a sample by a discharge generated between the first electrode and the second electrode by applying an alternating current voltage to either one of the first electrode and the second electrode, a mass spectrometry unit of analyzing an ion discharged from the sample discharging unit, and a light irradiating unit of irradiating an area of generating the discharge with light.