The invention provides an ultralow-pressure well leakage plugging method and belongs to the technical field of oil field well leakage plugging. According to the method, after a certain perforation well section is selected as an inlet of cement slurry, a squeezing packer is arranged in a casing pipe of the upper portion of the perforation well section in a setting mode, and a drillable one-way check valve is arranged under the squeezing packer; a squeezing pipe column is fed, an insertion pipe at the lower end of the squeezing pipe column is inserted into a socket of the packer so that the pipe column and the squeezing packer can be sealed, and the situation that due to the fact that plugging agents return to the portion above the squeezing packer in the plugging construction process, engineering accidents are caused can be prevented; gel spacer fluid is pumped into the squeezing pipe column, then the cement slurry is pumped, finally the gel spacer fluid is pumped, positive pressure squeezing is carried out, and therefore the gel spacer fluid and the cement slurry enter an oil-water layer or a channeling groove part to be sealed through the perforation well section serving as the inlet; pumping is stopped, the insertion pipe is pulled out, the one-way check valve is automatically closed, flow return is stopped, the pipe column is lifted to finish the operation of plugging the oil-water layer, kill fluid is poured, and a well is closed to wait on cement setting. The method has the advantages that site adaptation and leakage plugging strength are high, and leakage of the ultralow-pressure well can be plugged.