The invention discloses a method for preparing secondary zinc oxide from oxygen pressure leached zinc smelting solid waste residues. The method comprises the following steps that oxygen pressure leached zinc smelting solid waste residues are dried until the water content is 15% or below, and the solid waste residues are granulated by using a granulator; the solid waste residues are mixed with limestone, quartz stone and reducing coal, and are sent to an oxygen-enriched side-blown furnace; oxygen-enriched air is blown into a furnace during smelting, and chemical reactions such as sulfur makingand slagging are completed; sulfur in the slag generates SO2, and the SO2 enters an acid making system through a flue gas pipeline to produce industrial sulfuric acid; the molten slag is blown by a fuming furnace, secondary zinc oxide products are produced from smoke dust, and the fuming furnace slag is subjected to innocent treatment. According to the method, the problems that the smelting solidwaste produced in the zinc-oxygen pressure leaching process is difficult to stack and transport, valuable metal in the leaching residues cannot be recycled and the like are solved, and harmless treatment of the zinc-oxygen pressure leaching smelting solid waste is achieved. The method has the advantages that valuable metals such as lead, zinc, indium, germanium and silver can be recovered, industrial-grade secondary zinc oxide products can be prepared, the technological process is simple, the recovery rate of the valuable metals is high, and the energy consumption is low.