30results about How to "Enhanced sensitivity" patented technology

An electromagnetic digitizer having a sensor segment that includes a generally longitudinal network of conductive lines. Two or more conductive lines are coupled in parallel. To enhance sensitivity, the adjacent lines are interconnected along the longitudinal structure, using interconnections in the form of short lines, oriented at an angle. The sensor segments may be miniaturized, to facilitate integration into a display module using semiconductor fabrication processes. Various sensor array structures may be implemented using the sensor segment structures. The sensor array may include longitudinal sensor segments arranged in a parallel array. To further enhancing sensitivity of the sensor array, additional lines may be provided between adjacent longitudinal sensor segments. The sensor array may also include half loop (or U-shaped) sensor segments arranged in an overlapping parallel array, or full loop sensor segments arranged in an overlapping parallel array.

Compact terahertz spectrometer. The spectrometer includes an optical beam both for generating terahertz radiation for interaction with the sample and for use in a detector. A DC heterodyne detector uses a DC field-induced second harmonic wave at a sensor plasma to serve as a local oscillator. The spectrometer has a bandwidth orders of magnitude larger than conventional THz spectrometers.

A method, system, and apparatus provide for the creation and use of a holographic filter. The holographic filter has multiple superpositioned holograms within a volume holographic medium. These superpositioned holograms synthesize a filter shape with multiple peaks at specified positions. The shape of the holographic filter matches a spectrum of a substance. The holographic filter may then be used (e.g., in a spectrometer) to simultaneously detect peaks in the spectrum of the matching substance.

In an infrared detection sensor according to the present invention, all material constituting an upper portion of a sensing electrode in a supporting arm region is removed so that a supporting arm has low thermal conductivity. As a result, thermal conductivity of the infrared sensor structure is reduced, and the infrared detection sensor has excellent sensitivity.

Material condition monitoring may be performed by electromagnetic sensors and sensor arrays mounted to the material surface. The sensors typically have a periodic winding or electrode structure that creates a periodic sensing field when driven by an electrical signal. The sensors can be thin and flexible so that they conform to the surface of the test material. They can also be mounted such that they do not significantly modify the environmental exposure conditions for the test material, such as by creating stand-off gaps between the sensor and material surface or by perforating the sensor substrate.

A p channel field effect transistor in which the sensitivity of an enzyme can be enhanced by immobilizing the enzyme directly on an FET channel surface (diamond surface), as well as a sensor including the same, is provided. A diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals is treated under the action of glutaraldehyde OHC(CH2)3CHO (30), so that the glutaraldehyde (30) is immobilized on the diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals. Subsequently, urease (29) is further applied thereto, so that the amino group (31) of the urease (29) is bonded to the glutaraldehyde (30). That is, the urease (29) can be immobilized on the diamond surface (22) having mixed hydrogen terminals, oxygen terminals, and amino terminals. When the urea concentration is increased from 10−6 M to 10−2 M, the threshold voltage shifts by about 0.1 V in the positive direction, and the sensitivity to urea concentration of 30 mV / decade is exhibited.

A photo-sensing device is disclosed, comprising a photoelectric conversion semiconductor thin film, thin films for ohmic contacts to be provided to form an incident light window on one face of the photoelectric conversion semiconductor thin film, first and second ohmic electrodes installed on the thin films for the ohmic contacts, a connection wiring for short-circuiting the first and the second ohmic electrodes, an insulating film provided on the other face of the photoelectric conversion semiconductor thin film, and a first electrode provided on the face of the insulating film that does not contact the photoelectric conversion semiconductor thin film.

The present invention is a multipass unipoint optical cell used for the improved analysis of samples by transmission, reflection, Raman or fluorescence spectroscopy by the multiple reimaging of light through the same analysis point. The cell comprises two or more identical optical reimaging elements each consisting of two symmetrically opposing, identical, confocal, and coaxial parabolic reflective surfaces with the property to refocus any ray of light coming from the common focal point onto one of the parabolic surfaces, back to the same focal point by the other parabolic surface at an angle to the incoming ray. Two or more of these reimaging optical elements can be configured around the common focal point to form different multipass unipoint optical cell configurations, all the passes crossing in the analysis point where a sample is brought to interact with light, the effect of said interaction being enhanced in proportion to the number of passes.

The invention discloses a docetaxel nanometer micelle, a preparation method and application of the micelle to prepare medicines for treating tumor or drug-resistant tumor. The docetaxel nanometer micelle comprises 1 part by weight of docetaxel, 10-100 parts by weight of a carrier material and 0-10 parts of oil, wherein the average particle size of the docetaxel nanometer micelle is 10-200 nm. According to the preparation, the water solubility of docetaxel is substantially improved, the stability of the preparation is improved, the cycling time of docetaxel in blood is prolonged, the toxic and side effects of conventional preparations are reduced, docetaxel nanometer micelle can be driven to be targeted to tumor tissue through EPR effect, so that the anti-tumor curative effect of docetaxel is improved, and the docetaxel nanometer micelle overcomes the multidrug resistance of tumor.

Disclosed is a photothermographic material comprising on support a light-insensitive silver salt of an aliphatic carboxylic acid, a light-sensitive silver halide and a reducing agent for silver ions, wherein the photothermographic material further comprises a copolymer comprising a backbone comprising a chain having a monomeric repeating unit, represented by formula (1) and a chain having a monomeric repeating unit, represented by formula (2).

A retinal imaging device includes an optical system configured to (i) scan a portion of the retina of the eye with a line of light, (ii) descan reflected light from the scanned portion of the retina, and (iii) provide output light in a line focus configuration. The device includes a detection device including a linear array of asymmetric pixels having at least a 2:1 ratio of length to width, a detection device with multiple adjacent linear arrays, and / or a detection device using a time delay and integration (TDI) architecture.

A photo sensitive emulsion disclosed, comprising an organic silver salt, a photosensitive silver halide and a dispersing medium, wherein the organic silver salt is comprised of at least a first organic silver salt grains and a second organic silver salt grains which are different in average grain size from each other. A photothermographic material containing is also disclosed.

The present invention has two antennas to receive video / audio signals. The antennas tunes the frequency bands of the signals they receive in order to display two video / audio signals of two different bands. Or, if the antennas are tuned to receive video / audio signals of the same frequency band, the sensitivity on receiving signals is enhanced.

Sensitivity of thin film bulk acoustic resonance (TFBAR) sensors is enhanced by mass amplification and operating a high frequency.

The present invention relates to the formulations, methods and kits for reducing cytokine interleukin-17 (IL-17 or IL-17A) levels in both broncheoalveolar lavage fluid (BALF) and blood / serum and / or for the inhibition of p38 mitogen activating protein kinase (MAPK) activity involving the use of 17α-hydroxyprogesterone caproate (17-OHPC) or derivatives thereof. The formulation may be in the form of an inhalant containing effective amounts of 17-OHPC, and the formulation may be used in a method to treat IL-17 cytokine and / or p38 MAPK mediated auto-immune and auto-inflammatory diseases. Such diseases may include glucocorticoid (GC) insensitive related diseases or conditions. In alternate embodiment, the formulation may include the combined use of budesonide (BUD) with 17-OPHC.

A photodetector focal plane array system having enhanced sensitivity and angle-of-view, including: a substrate including a plurality of photosensitive regions; and a microcomponent disposed adjacent to each of the plurality of photosensitive regions operable for receiving incident radiation from a relatively wider area and directing the incident radiation into a relatively smaller area of the associated photosensitive region by, in part, one or more of waveguiding and scattering; wherein each of the microcomponents is centered with respect to a photodetector mesa of each of the plurality of photosensitive regions. Each of the microcomponents includes one of a microcone, a microcuboid, a micropillar, a core-shell micropillar, a microtubule, a pyramid, an inverted pyramid, and an arbitrary shape microcomponent—with a top surface having a a selected or arbitrary cross-sectional shape and a selected or arbitrary profile.

A vital-sign radar sensor using wireless frequency-locked loop includes a voltage-controlled oscillator (VCO), an antenna component, a mixer, a loop filter and a frequency demodulation component. The VCO outputs an oscillation signal to the antenna component via a output port, the antenna component transmits the oscillation signal to a subject as a transmitted signal and receives a reflected signal from the subject as a received signal, the mixer receives and mix the oscillation signal and the received signal into a mixed signal, the loop filter receives and filter the mixed signal to output a filtered signal, the filtered signal is delivered to the VCO via a tuning port, the frequency demodulation component receives and demodulates the oscillation signal to output a vital-sign signal.

The present invention relates to chemical total synthesis methods of six novel protein tyrosine phosphatase-1B (PTP1B) inhibitors and application of the inhibitors in the preparation of medicaments for treating type 2 diabetes mellitus (T2DM). The PTP1B inhibitors use one or more of the six compounds represented by the structural formulae 1, 2, 3, 4, 5 and 6, as active components. The compounds can enhance the sensitivity of an insulin receptor by inhibiting the activity of PTP1B, thereby having a favorable therapeutic effect on insulin-resistant T2DM.

The method of FloodGraphic graphically present location specific topographic and flood hazard data, including time-sensitive NWS watches and warnings inclusive of site-specific forecast flood depths via an array of particularly shaped and colored, site-specifically annotated, video-capable signsThe signs include vertical gradations in feet or meters in full scale presenting the elevation of the site, historic, and predicted future flood levels, specific to the location of each FG installation. FloodGraphic headquarters administers a program of information accumulation, vetting, information dissemination and management of installations.The method achieves a standard nationwide array of warning signs.The FloodGraphic method provides information and warning of actual past and forecast flood heights at a multiplicity of locations more effectively than any existing method by presenting data at each installation with reference to the grade level and a National Datum. No linking to or differentiation between the flood watch and flood warnings of the NWS is provided by any prior art.

A silver halide emulsion is disclosed, comprising silver halide grains, wherein at least 50% by number of the silver halide grains is accounted for by grains having an aspect ratio of less than 1.3, and the silver halide grains have an average chloride content of not less than 90 mol %, an average iodide content of from 0.02 to 2 mol % and an average bromide content of from 0.1 to 9 mol %, wherein the silver halide grains exhibit a coefficient of variation in iodide content among grains of less than 40%.

A touch panel includes a base substrate, a cover panel, a first electrode formed outside of a display region on a back surface of the cover panel, and a second electrode formed outside of the display region on a front surface of the base substrate. A pressure when the base substrate is pressed by the pointer through the cover panel is detected by measuring a change of a distance between the first electrode and the second electrode when the front surface of the cover panel is pressed as a change of electrostatic capacitance between the first electrode and the second electrode. The touch panel further includes a ground electrode formed on an outer peripheral side of the first electrode of the cover panel.

A six-port SIL radar includes an oscillation element, a transceiver element, a power coupling element and a six-port demodulation element. The six-port demodulation element is utilized to demodulate an oscillation signal from the oscillation element such that the operating frequency of the six-port SIL radar will not be restricted by hardware. Further, the power coupling element is configured to divide the oscillation signal into two signals that have equal power when received by the six-port demodulation element for signal-to-noise ratio optimization.

The disclosure relates to medical devices capable of enhancing ossification in a subject. More specifically, the disclosure relates to the use of devices comprising a releasable calcium sensing receptor agonist and a releasable calcium salt.

A photodetector includes: a semiconductor substrate having a first main surface and a second main surface; a first semiconductor layer that is of a first conductivity type, and is included in the semiconductor substrate and closer to the first main surface than to the second main surface; a second semiconductor layer that is of a second conductivity type different from the first conductivity type, and is included in the semiconductor substrate and interposed between the first semiconductor layer and the second main surface; a multiplication region that causes avalanche multiplication to a charge generated in the semiconductor substrate through photoelectric conversion; a circuit region disposed alongside the first semiconductor layer in a direction parallel to the first main surface; at least one isolation transistor disposed in the circuit region; and an isolation region interposed between the first semiconductor layer and the circuit region.

A contact sensor for the repeatable detection of small, high frequency mechanical vibrations in external systems is presented herein. The sensor includes a metal housing with an attachment device at one end and an output at the other end. Inside the metal housing is a core assembly that includes a piezo transducer assembly suspended or isolated between an actuator and a biasing device. The actuator may be in the form of a ceramic sphere that sits at least partially within a recess on the inside of the housing and is in physical contact with the piezo transducer assembly. The biasing device may be in the form of a spring that causes the piezo transducer assembly to be pressed against the actuator at a contestant and known amount of tension.

The present invention relates to a spectral sensor. The spectral sensor comprising: a light detecting element; a microlens; and an interference filter arranged between the light detecting element and the microlens, and configured to transmit light in one or more spectral bands; wherein the microlens has an effective focal length (F) exceeding a distance (D) between the microlens and the light detecting element. The microlens may be configured such that light refracted by the microlens, to be transmitted through the interference filter, converges towards a position (P) behind the light detecting element. The present invention further relates to an image sensor comprising a plurality of spectral sensors.

Methods of treating cancer or enhancing sensitivity to cancer therapies, including immunotherapies by increasing tumor mutation burden, are provided. The methods use therapeutics directed against DNA polymerase proofreading and / or mismatch repair enzymes such as MLH1, MSH2, MSH6 or PMS2. The therapeutics can be used alone, in tandem or in combination with other cancer therapies, in particular with immunotherapies. Also provided are antisense therapeutics targeting DNA polymerase proofreading and / or mismatch repair enzymes.

The invention relates to a diagnosis and therapeutic preparation for senile dementia and an application thereof, in particular to an application of ARHGAP11A gene, SPAG7 gene and C16ORF7 gene in preparing a diagnosis and therapeutic preparation for senile dementia. In order to solve the problem that molecular markers of senile dementia are scarce at present, the inventors carried out the high-throughput sequencing on peripheral blood samples of patients with senile dementia and healthy people, selected candidate genes, and confirmed that there was a good correlation between the candidate genes and senile dementia through molecular cell experiments, which laid a foundation for clinical gene diagnosis of senile dementia.