40results about How to "Difficulty is caused" patented technology

The present invention provides a drug delivery system to a posterior segment wherein a pharmaceutical composition comprising a drug and a vehicle is administered subconjunctivally to form a depot out of the vehicle, and thereby the drug is gradually released from the depot to enable an effective concentration of the drug to be maintained, the pharmaceutical composition comprising the vehicle which is in the form of gel subconjunctivally and the drug suspended in the vehicle.

There are provided: a curable resin composition having a high exposure sensitivity and a good developing property, and thereby capable of forming an accurate and precise pattern; a liquid crystal panel substrate on which a protective film for covering a color layer or spacers for a liquid crystal layer, by using the curable resin composition, hardly causing a color irregularity and contrast irregularity; and a liquid crystal panel using the liquid crystal panel substrate and having a superior display quality. The curable resin composition of the present invention comprises: a copolymer (a) having a molecular structure in which a constitutional unit including an acidic functional unit and a constitutional unit including a photocurable functional group are linked at least; a photopolymnerization initiator (b) having a tertiary amine structure; and a photocurable compound (c) having at least one acidic functional group and at least three photocurable functional groups.

A wiring board including a stacked wiring layer portion in which a dielectric layer and a conductor layer are stacked is formed on a core board portion, the stacked wiring layer portion including a stacked composite layer portion in which a polymer dielectric layer, a conductor layer and a ceramic dielectric layer are stacked in this order, the conductor layer being partially cut in the in-plane direction so as to have a conductor side cut portion, the ceramic dielectric layer being partially cut in the in-plane direction so as to have a ceramic side cut portion, the ceramic side cut portion and the conductor side cut portion being communicated to form a communication cut portion, a polymer constituting the polymer dielectric layer being filled in the communication cut portion so as to extend through the conductor side cut portion to the ceramic side cut portion.

N-Arylphenylacetamide derivatives represented by the following formula [I]:(wherein R1 is C1-6 alkoxy, etc.; R2 is hydrogen, —(CH2)m—N(R6)(R7) (m is an integer of from 1 to 4; R6 is hydrogen, C1-4 alkyl, etc., R7 is hydrogen, etc.), etc.; R3 is hydrogen, halogen, etc.; R4 is C6-10 alkyl, —Y—R8 (Y is a single bond, C1-6 alkylene, C2-6 alkenylene, C2-6 alkynylene, etc., R8 is aryl, C3-8 cycloalkyl, C6-15 polycycloalkyl, etc.), etc.; R5 is hydrogen, etc.; and X1 is hydrogen), or pharmaceutically acceptable salts thereof or hydrates or solvates of the same, and a pharmaceutical composition containing the same. These compounds are useful as preventives and / or remedies giving no pain at the early stage of administration, which are efficacious in oral administration and have potent analgesic and antiinflammatory effects.

In order to prevent the formation and subsequent breaking off of large agglomerations of dirt particles on the cover of a paper machine, at least one surface located opposite of the paper web and pertaining to at least one part of the elements forming a contact surface is provided, at least partially, with an average surface roughness of between 5 mum and 100 mum. (FIG. 4)

A cooking assistance robot is capable of efficient mixing using ingredients that are unlikely to be evenly heated. The cooking assistance robot performs cooking by physically moving ingredients in a cooking container selects a mixing direction for leveling a mountain and performs a mountain leveling operation in the selected mixing direction in a presence of a mountain of a specified height or higher in the cooking container.

The present invention provides a drug delivery system to a posterior segment wherein a pharmaceutical composition comprising a drug and a vehicle is administered subconjunctivally to form a depot out of the vehicle, and thereby the drug is gradually released from the depot to enable an effective concentration of the drug to be maintained, the pharmaceutical composition comprising the vehicle which is in the form of gel subconjunctivally and the drug suspended in the vehicle.

The present invention provides a ceramic substrate for use in an apparatus for manufacturing and inspecting semiconductors. The ceramic substrate comprises a through-hole having excellent tolerance performance against a drawing stress applied to an external terminal pin. The through-hole is provided with a projection which protrudes into the ceramic substrate made of aluminum nitride as primary component.

It is aimed to provide a cooking assistance robot and a cooking assistance method capable of efficient mixing, with which ingredients are unlikely to be unevenly heated.A cooking assistance robot for cooking by physically moving ingredients in a cooking container selects a mixing direction for leveling a mountain and performs a mountain leveling operation in the selected mixing direction in the presence of a mountain of a specified height or higher in the cooking container.

A transparent electrically-conductive film of the present invention comprises a transparent film substrate, a hard coat layer formed on one side of the transparent film substrate, a SiOx layer with a thickness of 10 nm to 300 nm that is formed on the hard coat layer by a dry process, and a transparent electrically-conductive thin layer with a thickness of 20 nm to 35 nm that is formed on another side of the transparent film substrate. The transparent electrically-conductive film has good resistance to moisture and heat and high durability against pen-based input and can be prevented from cracking during a punching process and also prevented from waving or curling even in a high-temperature, high-humidity environment.

N-Arylphenylacetamide derivatives represented by the following formula [I]: (wherein R<1 >is C1-6 alkoxy, etc.; R<2 >is hydrogen, -(CH2)m-N(R<6>)(R<7>) (m is an integer of from 1 to 4; R<6 >is hydrogen, C1-4 alkyl, etc., R<7 >is hydrogen, etc.), etc.; R<3 >is hydrogen, halogen, etc.; R<4 >is C6-10 alkyl, -Y-R<8 >(Y is a single bond, C1-6 alkylene, C2-6 alkenylene, C2-6 alkynylene, etc., R<8 >is aryl, C3-8 cycloalkyl, C6-15 polycycloalkyl, etc.), etc.; R<5 >is hydrogen, etc.; and X<1 >is hydrogen), or pharmaceutically acceptable salts thereof or hydrates or solvates of the same, and a pharmaceutical composition containing the same. These compounds are useful as preventives and / or remedies giving no pain at the early stage of administration, which are efficacious in oral administration and have potent analgesic and antiinflammatory effects.

An alkaline secondary battery has a positive electrode plate having a predetermined shape, formed from a long-shaped electrode substrate. A manufacturing method thereof comprises an impurity detecting step for applying X-rays to the electrode substrate to acquire a transmitted image, and detecting based on the transmitted image whether a metal impurity particle made of a metal dissolved at a positive electrode potential and deposited at a negative electrode potential exists in the electrode substrate. The method includes a marking step for, when the metal impurity particle exists, applying a marking indicative of its particle-existing portion on the electrode substrate.

The present invention provides a functional coated product having excellent adhesion properties of a coating to a substrate, hardly causing the deterioration of the substrate and the coating due to a photocatalyst, hardly having dirt because the smoothness of the surface coating is high, and having high photocatalytic action; a method for producing the same and the use thereof.The coated product of the present invention has the first coating layer comprising a cured coating made of an acryl-modified silicone resin coating material, which is formed on the surface of the substrate, and the second coating layer comprising a cured coating made of a functional coating material containing the photocatalyst, which is formed con the surface of the first coating layer. When producing such a coated product, the acryl-modified silicone resin coating material is applied to the surface of the substrate as the first coating layer and it is semi-cured. After that, a photocatalyst-containing functional coating material is applied to the surface of this first coating layer in a semi-cured condition and then both of the coating layers are cured. Thereby, a coated product having a higher effect can be obtained.

This invention relates to a pneumatic tire provided at its bead portion with a rubber chafer (4) and covered at its inner surface with an innerliner (5), wherein a toe rubber (6) is further arranged on a toe end part of the bead portion so as to overlap with the rubber chafer (4) and the innerliner (5) and locate at least outside the innerliner (5) at the overlapped portion with the innerliner (5), and a rubber composition A containing at least one of butyl rubber and halogenated butyl rubber as 20-40 mass % of a rubber component is used in the toe rubber (6).

[Problems] To provide an absorbent article that hardly causes skin roughness.[Means for Solving Problems] An absorbent article 10 comprising a face sheet 1 and an absorbent body 3 in this order, wherein the face sheet 1 is at least one of concavo-convex or convexo-flat heat-embossed sheet and concavo-convex or convexo-flat ultrasonic-embossed sheet.

A panel of a plasma display apparatus includes a front substrate and a back substrate arranged in opposition to this front substrate, and an outer circumferential portion of the front substrate and an outer circumferential portion of the back substrate are adhered to each other by a sealing material. The panel is held on a front side of a chassis base portion of a chassis member. A conductive member fixed to an outer circumferential portion of the chassis member includes a first bent portion bent to a back side at a portion located inside a portion where the conductive member is fixed to the chassis member and a first extending portion extending to the back side from the first bent portion. Occurrence of a crack of the panel due to drop impact, vibration, and external force can be prevented.

A charging member is provided, suppressing the occurrence of streak-like images resulting from resistance increase caused by degradation of the charging member due to electric conduction for a long period. A process cartridge and an electrophotographic apparatus are also provided, suppressing the occurrence of streak-like images and stably forming a high-quality electrophotographic image.The charging member comprises an electroconductive support and an electroconductive surface layer, the surface layer comprising at least one of the compounds respectively represented by formula (1), formula (3), and formula (4) defined in the specification, a binder resin, and a conducting agent. The process cartridge and the electrophotographic apparatus use the charging member.

The liquid crystal panel 1 of the present invention comprises a liquid crystal cell 2, a first polarizer 31 disposed on one surface side of the liquid crystal cell 2, a second polarizer 41 disposed on the other surface side of the liquid crystal cell 2, and first optical compensation layer 5 and second optical compensation layer 6 disposed between the first polarizer 31 and second polarizer 41, and the liquid crystal cell 2 satisfies a relationship of 0.8<Re[450] / Re[550]<1, the first optical compensation layer 5 satisfies relationships of the Nz coefficient is from 0.8 to 1.4 and 0.8<Re[450] / Re[550]<1, and the second optical compensation layer 6 satisfies relationships of nx=ny>nz and 0.98<Re[450] / Re[550]<1.04.The liquid crystal panel of the present invention is hardly generated color shift when the panel is viewed from all azimuth angle directions and polar angle directions, so that the liquid crystal panel is excellent in color display characteristics.

An optical module having a high-moisture-proof package structure in which dew condensation does not occur is provided.An optical module includes optical components including a light source, a pedestal on which the optical components are mounted, a cover which is combined to the pedestal to seal the optical components, and an emitting window disposed in the cover to take light from the light source outside. The pedestal and the cover are sealed with an O ring and a liquid seal material such that a compression direction of the O ring and a compression direction of the liquid seal material are almost perpendicular to each other.

A production process of a polymerized toner composed of polymer particles, including a step of polymerizing a polymerizable monomer composition containing a colorant and a polymerizable monomer in the presence of a polymerization initiator in an aqueous dispersion medium, wherein, in a stripping treatment step, the dispersion containing the polymer particles is introduced into an evaporator to conduct the stripping treatment by a method, in which a gas is blown into the dispersion within the evaporator to discharge volatile organic components including an unreacted polymerizable monomer out of the evaporator concomitantly with the gas, and both inert gas and saturated steam are used as the gas blown into the dispersion.

An object of the present invention is to provide a fuel cell including a reaction gas supply path which makes it difficult to cause water condensation in a region near an end plate. A fuel cell of the present invention comprises a cell stack 2 having a reaction gas passage 13a inside thereof and having on one end surface thereof a reaction gas supply inlet 17 from which a reaction gas is supplied to the reaction gas passage 13a, a joint 5 connecting the reaction gas supply inlet 17 to an external pipe P for supplying the reaction gas, plate-shaped end members 3, 4 which are disposed on one end surface of the cell stack 2 and have through-holes 21, 23 into which the joint 5 is inserted so as not to contact inner wall surfaces thereof, and a closing member 9 for substantially closing a space formed between the joint 5 and the inner wall surfaces of the through-holes 21, 23.

A method including (a) preparing an insulating substrate, and (b) forming n (n is an integer equal to or greater than 9) through holes on the insulating substrate in a through hole density in a range of 1000 pieces / cm2 to 20000 pieces / cm2 at a pitch P (μm) in a range of 20 μm to 300 μm, wherein (b) is performed on a front surface of the insulating substrate and includes (b1) forming a first through hole at a first target position, (b2) forming a second through hole at a second target position, wherein a distance between the first target position and the second target position is greater than the pitch P (μm) . . . , and (bn) forming an n-th final through hole at an n-th target position, wherein a distance between the (n−1) target position and the n-th target position is greater than the pitch P (μm).