The invention relates to an automatic die-cutting machine for transparent plastic antibacterial food packaging boxes, which includes a workbench, a belt conveyor, a die-cutting device and a collecting device. A belt conveyor is installed on the left side of the workbench. There is a stepped groove at the right end of the conveyor, a die-cutting device is installed on the right side of the stepped groove, and a collection device is installed at the right end of the die-cutting device. The die-cutting device includes a telescopic bracket, a positioning frame, an inverted L-shaped frame, and an electric cylinder. , support plate, cutting frame and push piece frame, the present invention cooperates with the workbench and the belt conveyor to guide and position the packaging box, and the packaging box is positioned by the die cutting device, while cutting and deburring are performed, and the The cut packaging box moves to the right, and is palletized and collected by the collection device, and waste and burrs are collected at the same time.