The invention discloses a
solvent auxiliary
electrospray ionization device and a method for achieving
electrospray ionization by utilizing the same. The device comprises an
electrospray channel and a sample leading-in channel, an included angle between the axis of the electrospray channel and the axis of the sample leading-in channel is an
acute angle, an included angle between the axis of the electrospray channel and the axis of the
mass spectrum sample feeding channel is an
acute angle, the axis of the electrospray channel, the axis of the sample leading-in channel and the axis of the
mass spectrum sample feeding channel are intersected in the same plane, and the tip end of the electrospray channel is contacted with the tip end of the sample leading-in channel. The method for achieving
electrospray ionization by utilizing the device comprises the steps of enabling auxiliary
solvent to flow into the electrospray channel; enabling solution of a sample to be tested to be lead into the electrospray channel; when the auxiliary
solvent is mixed with the solution of the sample to be tested, removing the solvent through electrospray. The solvent auxiliary
electrospray ionization device and the method for achieving
electrospray ionization by utilizing the solvent auxiliary electrospray
ionization device not only can be applied to
mass spectrometry of chemical reactions in electrospray-unfriendly solvent, but also can be compatible with commonly used mass spectrometers, and is strong in practicality.