The invention discloses preparation and applications of echinococcus multilocularis resistant
vesicle wall tissue (malpighian layer and
cuticle layer)
monoclonal antibody. The
larva of echinococcus multilocularis parasitizes in
human body and causes multilocular hydatidosis which is also known as echinococcus multilocularis
disease. The
larva usually parasitizes in the liver, and the
disease is usually confused with tumors or other diseases. The invention relates to the scientific research, diagnosis, and treatment of echinococcus multilocularis
disease, and provides a mouse-originated
hybridoma cell strain. The
monoclonal antibody secreted by the mouse-originated
hybridoma cell strain can carry out specific binding with
vesicle wall tissue (malpighian layer and
cuticle layer) of echinococcus multilocularis, so the
antibody can be used to carry out immunohistochemical
specific staining on
pathological tissues of the echinococcus multilocularis disease. The
antibody titer can reach 1:105, and the antibody has a very strong sensitivity and specificity. The antibody can be used for the immunological
pathological diagnosis of the echinococcus multilocularis disease. The
monoclonal antibody can also be coupled with
chemotherapy drugs or
radionuclide to prepare target drugs and diagnosis reagents. The antibody can be applied to the scientific research related with echinococcus multilocularis too.