35results about How to "Take the correct dose" patented technology

The purpose of the invention is to provide a Pudilan children's antiviral oral pellet gel and a preparation method thereof. The preparation method comprises the following steps: adopting a gel matrix, extracting Radix Scutellariae, Herba Taraxaci, Corydalis bungeana Turcz. and isatis root, preparing pellets by using extracted effective components, and uniformly dispersing the pellets in a gel. The prepared gel can be a solid gel, a semisolid gel or a xerogel. The method effectively covers the bad smell of medicines, solves the mouthfeel problem of the medicines, and allows the sweet oral pellet gel loved by children to be prepared, and the sweet and smooth mouthfeel of the oral pellet gel makes children easily take the medicine. Traditional Chinese medicines are combined with the gel dosage form to improve the children's administration long-term single dosage form, and the oral pellet gel has the efficacies of heat clearing, detoxification, antibiosis and inflammation prevention, and also has the advantages of high content of the effective component, small administrating dosage, stable preparation and good curative effect.

The invention discloses a preparation method of compound bamboo leave flavone dripping pill, belonging to the technical field of traditional Chinese medicine preparation. In the dripping pill preparation, Chinese herbal medicine bamboo leaves and mimosa are used as raw materials, a flavone extractive is obtained by extracting according to a certain method, and then the flavone extractive and pharmaceutical accessories used as matrix are processed by a certain method in proportion to prepare the final product. The dripping pill has the characteristics of high bioavailability, quick dissolution time, fast absorption by oral taking, high content of effective ingredients, accurate dosage, and convenient taking and carrying; the invention also has the functions of anti-lipid overoxidation, free radical removal, blood fat and cholesterolemia reduction, coronary blood flow increase, and myocardial ischemia melioration, and can be used for resisting oxidation, resisting aging, lowering blood fat, preventing and curing arteriosclerosis, cerebral ischemia, miocardial infarction and other diseases as well as the adjuvant therapy for cancer.

The present invention relates to an easily-disintegrated freeze-drying molding preparation having any form, and a preparation method thereof, particularly to a freeze-drying molding preparation and a preparation method thereof, wherein water or a freeze-drying preparation raw liquid is completely stirred into ice sand during freezing, the remaining raw material and the remaining auxiliary material are further mixed into the ice sand, the obtained mixture is loaded into a certain mold, shaping is performed, freeze-drying is performed to obtain the easily-disintegrated freeze-drying molding preparation, and the obtained easily-disintegrated freeze-drying molding preparation has an any molding shape and mainly contains an active component, an adhesive and a disintegrating agent.

The invention relates to a freeze-drying preparation and a preparation method thereof. The freeze-drying preparation comprises an effective amount of an active component and a combined binder system comprising a low-temperature binder and a freeze-drying binder. The low-temperature binder is one or a combination of several of C1-C16 alcohol, grease, a surfactant, and high-molecular polymer, and the freeze-drying binder is artificial or natural high-molecular polymer, cellulose ethers, modified starch, hyaluronic acids, albumin, dextran, chitosan and different-molecular-weight products thereof, sodium alginate, PVP, PVA, polyethylene glycol, agar, polyamino acid, glycan or a combination thereof. A formula system comprising the component above matches a certain process, and a freeze-drying preparation product with any shape and a preparation method thereof are provided.

The invention discloses a medicament composition used for treating orthopedics injuries and a preparation method thereof, wherein the medicament composition comprises natural copper (roasted, quenching in vinegar), ground beeltle (liquorice-processed), rhubarb (wine-processed), drynaria rhizome, angelica tail (wine-processed), frankincense (roasted), myrrh (roasted), borax (roasted), dragon blood,pseudo-ginseng and borneol. The invention aims at replenishing the shortages of the prior drug preparation used for treating orthopedics injuries and providing a water-bindered pill which has smallerpill, and is easy to be swallowed and received by a patient. The preparation method for treating traumatic injuries comprises the following steps: crashing native copper and other ingredient of eleven ingredient except for pseudo-ginseng and borneol into fine powder; additionally taking pseudo-ginseng and borneol and respectively grinding into finest powder, mixing and grinding the finest powderand the fine powder, adding 30g of microcrystalline cellulose and appropriate amount of carboxymethyl starch sodium to reach the total amount of 200g, evenly mixing, adding water as wetting agent, evenly mixing, lumping for 5 minutes, making into pill strips, grading and rounding, drying, polishing, drying and split charging to form the finished product; and in order to guarantee the product quality, all operations are carried out in a clean and dry environment. The medicament composition is convenient for selecting dosages by patients, avoids the defects of poor mouthfeel and inaccurate taking dosages in the prior drugs; and meanwhile, the taking dosage is more accurate, the mouthfeel is greatly improved and easy to be received by patients, the production devices and technological requirements in pill making process are simple, and the concentrated pill prepared by a plastic method has high finished product ratio and stable quality.

The invention discloses a child-type oral anti-epileptic pharmaceutical gel unit. Every 1000ml of child-type oral anti-epileptic pharmaceutical gel unit comprises the following components: 0.1-150g of anti-epileptic drug, 2-60g of gel matrix, 0.5-2g of improving agent, 3-500g of sweetening agent, 1-5g of aromatic agent, 0-1.5g of preservative, 0-20ml of pH regulating agent and the balance of water. The invention also discloses a preparation method of the child-type oral anti-epileptic pharmaceutical gel unit. The child-type oral anti-epileptic pharmaceutical gel unit adopts multiple innovations including water-soluble gel matrix and the improving agent with unique proportion and the like, and can be generally used for different gel agent forms such as QQ candies, jellies, smoothies or xerogel.

The present invention relates to a domperidone gel preparation for curing reflux esophagitis. Said preparation includes active component and matrix, in which the active component includes the solution made up by using domperidone, polyvinylpyrrolidone and water. Its taste is good, and its stability is better.

The invention relates to a Chinese herb preparation for remedying hepatitis b and a preparation method thereof. The Chinese herb preparation is formed by rhubarb, paeonia lactiflora pallas, herba artemisiae capillaries, radix bupleuri, cyrtomium fortunei, ginseng, milk veteh and liquorice, which has the effects of clearing heat and toxic material, smoothing liver and strengthening spleen. The invention is mainly used to remedy the stasis of liver energy, the besiegment of spleen by dampness and hepatitis b. Compared with the prior technology, the invention has the advantages of simple preparation technology, active ingredient of high content, easy quality control, exact dosage, high bioavailability, notable curative effect and good stability.

The invention relates to a method for preparing freeze-drying excipients of any shape by utilizing multiple molds and a product made thereby, in particular to a preparation method for obtaining freeze-drying excipients mostly containing active ingredients and binders by utilizing multiple molds and the product made thereby.

The invention provides a lyophilized preparation and a preparation method thereof. The preparation method comprises the following steps: a) mixing preparation raw materials, and carrying out congelation, so that a soft ice mixture is obtained, wherein the preparation raw materials comprise active ingredients, a binding agent and water, the mass ratio of the active ingredients to the binding agentis (0-100):(0-100), and the contents of the active ingredients and the binding agent are not zero at the same time; b) releasing the soft ice mixture into an environment by adopting a filling machine,and carrying out consolidation forming, so that a condensate is obtained, wherein the filling machine is selected from a liquid moving device, a plunger pump, a screw pump, a gear pump or peristalticpump; and c) carrying out lyophilization on the condensate, so that the lyophilized preparation is obtained. The prepared lyophilized preparation is controllable in shape and relatively high in drugloading capacity; and the lyophilized preparation is good in strength, high in disintegration speed and good in solubility. Experimental results show that the drug loading capacity of the lyophilizedpreparation is 0.01-99.9%; friability of the preparation is less than 0.1%, disintegration time of the preparation in water is shorter than 15s, and complete dissolution time is shorter than 15s.

The invention relates to a method of preparing a freeze-drying excipient of any shape by using rolling dies and a product prepared by the method, particularly a method of preparing a freeze-drying excipient of any shape and mainly comprising an active component and an adhesive by using rolling dies and a product prepared by the method. The problem that freeze-drying excipients have a single form is overcome. Dies can be designed according to needs to prepare the freeze-drying excipient into various required shapes, and therefore the freeze-drying excipient can have various forms and structures (double-layer sheets and multi-layer sheets), and continuous production can be achieved. The production efficiency is increased and the cost is effectively reduced.

The invention discloses a pharmaceutical preparation containing rifaximin gel and rifaximin oral emulsion and a preparation method thereof, wherein the gel comprises rifaximin and a gel matrix, the mass ratio of the rifaximin to the gel matrix is (2-80):(5-64), and the gel matrix comprises 2-30 parts by weight of a water-soluble gel matrix and 0.5-2 parts by weight of a modifier; and the rifaximin oral emulsion comprises 1-40 parts by weight of rifaximin, 50-350 parts by weight of an oil phase, 1-300 parts by weight of an emulsifier, and 0-150 parts by weight of a co-emulsifier. In the preparation, on the premise of guaranteeing that the dose of a main drug is appropriate, through the selection of auxiliary materials and preparation methods, rifaximin is prepared into gel or oral emulsion, thereby facilitating the oral administration and absorption of drugs, and achieving relatively high bioavailability. Meanwhile, a newer and better dosage form choice is provided for clinic.

The invention relates to a preparation method of a freeze-dried preparation and a product prepared by the same, in particular to a preparation method of an arbitrarily-shaped active ingredient and / or binding agent-containing freeze-dried preparation obtained by coagulating and freezing an ingredient mixture into a soft ice mixture, putting in a certain mold, shaping, de-molding and finally freezing and drying, and a product prepared by the same.

The invention relates to a roller die method for preparing a freeze-dried preparation and a product prepared with the method. A soft ice mixture is prepared from a freeze-dried preparation stock solution, raw and auxiliary materials can be further mixed with the soft ice mixture, then, the mixture is quantified, set and cured with a relative rotation type roller die combined mold, a zero adhesion technology is adopted for demolding, and finally, the freeze-dried preparation which is in any shapes and mainly contains water, active components and a binder is obtained through freeze-drying and dehydration.

The invention provides a process for preparing medicament for post partum rehabilitation, which consists of steps of proportioning raw materials, rouging, watering and boiling, merging the grilling liquid, stewing and settling, filtering to obtain filtrate, concentrating into clear grease, drying brown sugar in vacuum drying oven, disintegrating and passing through 100 mesh sieve, mixing clear grease, sugar powder and starch gum by a ratio of 1:3:1, charging 85% ethanol, preparing soft material, granulating and low temperature drying, finally split charging to obtain the end product.

A sweet pill of acetylaminophenol is disclosed, which is suitable for children. Its preparing process is also disclosed.

The invention relates to a method for preparing a freeze-dried preparation in any shape and a product made according to the method, and particularly relates to a preparation method of a freeze-dried preparation which is prepared and obtained through sufficiently agitating and making a freeze-dried preparation stock solution or freeze-dried preparation water into a smoothie during refrigeration, capably further mixing raw and auxiliary materials into the smoothie and then loading an obtained mixture into a certain mold to carry out freeze drying, is in any shape and mainly contains an active component and a binder, and a product made according to the method.

The invention relates to a method for preparing a freeze-dried excipient preparation in any shape and a product prepared in accordance with the method, and in particular to a preparation method of a freeze-dried excipient preparation which is in any shape and mainly consists of an active ingredient and a binding agent and a product prepared in accordance with the method, wherein the preparation method of the freeze-dried excipient preparation comprises the following steps: fully stirring a freeze-dried excipient preparation stock solution, which is frozen, into ice shavings, and freeze-drying the ice shavings in a certain die.

The invention relates to a preparation method of a freeze-drying excipient, and particularly relates to the preparation method of the freeze-drying excipient which facilitates breaking away from the forming mould after freeze-drying by surface treatment of a forming mould.

The invention relates to a medicinal oral preparation for treating throat pain, furuncle and carbuncle, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying.

The invention discloses a preparation method of compound bamboo leave flavone dripping pill, belonging to the technical field of traditional Chinese medicine preparation. In the dripping pill preparation, Chinese herbal medicine bamboo leaves and mimosa are used as raw materials, a flavone extractive is obtained by extracting according to a certain method, and then the flavone extractive and pharmaceutical accessories used as matrix are processed by a certain method in proportion to prepare the final product. The dripping pill has the characteristics of high bioavailability, quick dissolutiontime, fast absorption by oral taking, high content of effective ingredients, accurate dosage, and convenient taking and carrying; the invention also has the functions of anti-lipid overoxidation, free radical removal, blood fat and cholesterolemia reduction, coronary blood flow increase, and myocardial ischemia melioration, and can be used for resisting oxidation, resisting aging, lowering blood fat, preventing and curing arteriosclerosis, cerebral ischemia, miocardial infarction and other diseases as well as the adjuvant therapy for cancer.

The invention discloses a diflunisal dry suspension and a preparation method thereof. The dry suspension is obtained by the following steps: 20 to 200 parts by weight of diflunisal, 200 to 1200 partsby weight of a filler, 100 to 400 parts by weight of a binder, 10 to 200 parts by weight of a flow aid, 5 to 10 parts by weight of a sweetener, and 1 to 3 parts by weight of aroma are respectively weighed, the materials are crushed, passed through a 80 mesh sieve, and uniformly mixed, and a metered powder dispenser is used to prepare the diflunisal dry suspension. Compared with the existing preparation technology, the diflunisal dry suspension prepared by the invention has the advantages of convenient administration, accurate dosage, and convenient carrying.

The invention provides an indirubin self-microemulsifying preparation, which is prepared from the active ingredient indirubin, an oil phase, an emulsifier and a co-emulsifier. The invention also provides a preparation method of the indirubin self-microemulsion preparation, and a self-microemulsion sustained-release microcapsule containing the indirubin self-microemulsion preparation. The solubility of the indirubin self-microemulsifying preparation in the present invention is at least 97.39 times higher than that of the indirubin crude drug, and the quality evaluation result of the in vitro preparation is good, and the purpose of solubilizing the indirubin is achieved. The present invention aims to use self-emulsification as a drug-loading system to achieve the purpose of solubilizing and promoting penetration of indirubin, and uses microencapsulation technology to conduct slow-release research on indirubin self-emulsifying preparations to reduce the number of times of taking and prolong the drug effect. time, with the aim of enhancing patient compliance.

The invention relates to a compound Chinese hawthorn leaf total flavone dripping pill and a preparation method thereof, and can effectively solve the problems of enhancing the human body immunity and human endurance. The compound Chinese hawthorn leaf total flavone dripping pill is prepared from raw material medicines with the total amount of 100 percent and mixed base material, wherein the raw material medicines include the following components by weight percentage: 10 to 30 percent of Chinese hawthorn leaf total flavone extract, 10 to 30 percent of mulberry leaf total flavone extract, 10 to 30 percent of okra leaf total flavone extract, 5 to 20 percent of melicope patulinervia total flavone extract, and 10 to 30 percent of wenchow orange peel total flavone extract. The method for preparing the compound Chinese hawthorn leaf total flavone dripping pill comprises the following steps: heating and melting the mixed base material, mixing the heated and melted mixed base material with the raw material medicines, evenly stirring the mixture, completely discharging air bubbles, dripping the melted liquid medicine in a condensing agent, condensing the melted liquid medicine into pills, and then filtering the condensing agent on the surface of the pill. The compound Chinese hawthorn leaf total flavone dripping pill is rich in raw materials and easy to produce, remarkably enhances the human endurance and human immunity, has the functions of fighting against arteriosclerosis, softening the blood vessels, resisting fatigue, oxidation and radiation, and delaying senility, can be used for enhancing immunity, resisting oxidation and aging, softening the blood vessels and preventing arteriosclerosis, can be absorbed quickly, and is high in content of active components.

The invention relates to a child-type oral nucleoside antiviral pharmaceutical gel unit based on an improved gel matrix, the gel unit comprising a gel carrying nucleoside antiviral drugs, and a hermetic package for holding the gel , the gel uses an improved gel matrix, the weight ratio of the nucleoside antiviral drug to the improved gel matrix is ​​1-150:2-62, and the improved gel matrix includes 2-60 weight A water-soluble gel base of 0.5-2 parts by weight and a modifier of 0.5-2 parts by weight. The beneficial effect of the present invention is that it provides a child-type antiviral gel unit based on the improved gel matrix, which adopts a number of innovations including a unique ratio of water-soluble gel matrix and modifier, and can be used in general Different gel forms such as QQ candies, jellies, smoothies or xerogels.

The purpose of the invention is to provide a Pudilan children's antiviral oral pellet gel and a preparation method thereof. The preparation method comprises the following steps: adopting a gel matrix, extracting Radix Scutellariae, Herba Taraxaci, Corydalis bungeana Turcz. and isatis root, preparing pellets by using extracted effective components, and uniformly dispersing the pellets in a gel. The prepared gel can be a solid gel, a semisolid gel or a xerogel. The method effectively covers the bad smell of medicines, solves the mouthfeel problem of the medicines, and allows the sweet oral pellet gel loved by children to be prepared, and the sweet and smooth mouthfeel of the oral pellet gel makes children easily take the medicine. Traditional Chinese medicines are combined with the gel dosage form to improve the children's administration long-term single dosage form, and the oral pellet gel has the efficacies of heat clearing, detoxification, antibiosis and inflammation prevention, and also has the advantages of high content of the effective component, small administrating dosage, stable preparation and good curative effect.

The invention provides a preparation method of pressed pills. The invention also provides a pill. According to the method and the device for preparing the pressed pills, the appearance of the pills is improved, the consistency of weight differences among the pills is improved, the product quality is improved, the production efficiency is improved, the labor intensity is reduced, the energy consumption in a production process is reduced, the method is more environment-friendly and energy-saving, the damage to medicine components in the production process is reduced, and the curative effect of products is improved.

The invention discloses a pharmaceutical preparation containing rifaximin gel and rifaximin oral emulsion and a preparation method thereof, wherein the gel comprises rifaximin and a gel matrix, the mass ratio of the rifaximin to the gel matrix is (2-80):(5-64), and the gel matrix comprises 2-30 parts by weight of a water-soluble gel matrix and 0.5-2 parts by weight of a modifier; and the rifaximin oral emulsion comprises 1-40 parts by weight of rifaximin, 50-350 parts by weight of an oil phase, 1-300 parts by weight of an emulsifier, and 0-150 parts by weight of a co-emulsifier. In the preparation, on the premise of guaranteeing that the dose of a main drug is appropriate, through the selection of auxiliary materials and preparation methods, rifaximin is prepared into gel or oral emulsion, thereby facilitating the oral administration and absorption of drugs, and achieving relatively high bioavailability. Meanwhile, a newer and better dosage form choice is provided for clinic.

The present invention relates to a domperidone gel preparation for curing reflux esophagitis. Said preparation includes active component and matrix, in which the active component includes the solution made up by using domperidone, polyvinylpyrrolidone and water. Its taste is good, and its stability is better.

The invention discloses a bee glue drop pill for treating dentalgia, which is a medicinal composition with the functions of relieving pain, haemostasis and the auxiliary treatment for periodontitis. The pharmaceutical composition is prepared from bee glue as the raw material through the conventional drop pill preparing process.