The invention belongs to the technical field of heating and refrigerating temperature control and particularly relates to a semi-conductor temperature control device for heating and refrigerating by using a circulating medium. The temperature control device is composed of a medium circulating system and a temperature control system. Components comprise a heat insulation container, the circulating medium, a circulating driving pump, a flow controller, a heat exchanging plate, a semi-conductor refrigerating plate, a heat / cold dissipating component, a digital display temperature control instrument and a direct-current power supply system. The device has the capacity for controlling external system temperature, can achieve program temperature rising and dropping operation and constant-temperature operation in a wide temperature interval, supports remote monitoring, and meets simple and complex temperature control requirements in scientific research and production. The flowing medium is used in a circulation mode, resources can be saved, noise is avoided during work, the device is easy to miniaturize, and good medium and low temperature control environments can be provided for scientific research and production in the fields of chemistry, chemical engineering, materials, food, medicine, electronics and the like.