35results about How to "Improve disease symptoms" patented technology

The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human depression predisposing gene, specifically the apoptotic protease activating factor 1 (APAF1) gene, some mutant alleles of which cause susceptibility to depression. More specifically, the invention relates to germline mutations in the APAF1 gene and their use in the diagnosis of predisposition to depression. The invention also relates to the prophylaxis and / or therapy of depression associated with a mutation in the APAF1 gene. The invention further relates to the screening of drugs for depression therapy. Finally, the invention relates to the screening of the APAF1 gene for mutations / alterations, which are useful for diagnosing the predisposition to depression.

The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human obesity and diabetes predisposing gene, specifically the TBC1D1 gene, some mutant alleles of which cause susceptibility to obesity and / or diabetes. More specifically, the invention relates to germline mutations in the TBC1D1 gene and their use in the diagnosis of predisposition to obesity and diabetes. Finally, the invention relates to the screening of the TBC1D1 gene for mutations / alterations, which are useful for diagnosing the predisposition to obesity.

The present invention relates to polyamides with a tail comprising a linker and an end-group. A preferred end-group is isophthalic acid and derivatives thereof. Polyamides of the invention are capable of entering the nucleus of cells. Polyamides of the invention are capable of selectively binding DNA. The invention also relates to methods of using the polyamides in therapy and research.

The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect human diabetes mellitus predisposing gene, specifically the angiotensinogen (AGT) gene, some mutant alleles of which cause susceptibility to insulin-dependent diabetes mellitus (IDDM). More specifically, the invention relates to germline mutations in the AGT gene and their use in the diagnosis of predisposition to diabetes. The invention also relates to the prophylaxis and / or therapy of diabetes associated with a mutation in the AGT gene. The invention further relates to the screening of drugs for diabetes therapy. Finally, the invention relates to the screening of the AGT gene for mutations, which are useful for diagnosing the predisposition to diabetes.

The invention provides a Chinese medicinal oral liquid for smoothing heart and enhancing intelligence. The Chinese medicinal oral liquid is prepared from the following Chinese medicinal raw materials: nutgrass galingale rhizome, cortex eucommiae, rehmannia root, Chinese taxillus twig, large-leaved gentian, twotooth achyranthes root, south dodder seed, turmeric root-tuber, thinleaf milkwort root-bark, bamboo shavings, immature bitter orange, spina date seed, uncaria, dens draconis, bamboo juice, sappan wood, prepared common monkshood daughter root, magnet, common burreed rhizome, peppermint, Chinese ephedra, dragon bone and red date. The Chinese medicinal oral liquid has a good clinical effect on upset major depression patients at every stage, a good treatment effect can be achieved at an administration initial stage, symptoms such as degradation of learning memory, insomnia, early awakening, dreaming, anxiety and the like are relieved, and the pain of patients is relieved greatly; theoral liquid plays a good role for preventing dysphoria of people who are under high working pressure and concentrate intensively every day; and the oral liquid has the outstanding effect of no toxic or side effect, can be used for rapidly improving symptoms of patients, and has the advantages of difficulty in relapsing, low treatment cost, and the like.

The invention relate to the discovery of a depression associated AKAP9 predisposing variant. The invention provides for detecting the variant. The invention also provides methods for screening for antidepressants based on modulating AKAP9 mediated signaling.

The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human depression predisposing gene, specifically the apoptotic protease activating factor 1 (APAF1) gene, some mutant alleles of which cause susceptibility to depression. More specifically, the invention relates to germline mutations in the APAF1 gene and their use in the diagnosis of predisposition to depression. The invention also relates to the prophylaxis and / or therapy of depression associated with a mutation in the APAF1 gene. The invention further relates to the screening of drugs for depression therapy. Finally, the invention relates to the screening of the APAF1 gene for mutations / alterations, which are useful for diagnosing the predisposition to depression.

Provided feed for controlling pig influenza comprises the raw materials: corn, soybean meal, edible salt, fish meal, soybean oil, zinc methionine, copper lysine, tryptophan, vitamin A, vitamin E, ethoxyquin and a traditional Chinese medicine composition feed additive for controlling pig influenza. The traditional Chinese medicine composition feed additive is abundant in drug source, relatively low in residual toxicity or free of residual toxicity, small in side effect and not easy for generating of drug resistance, is capable of regulating body immune function, inhibiting virus replication and improving disease symptoms, and has substantial effect on controlling pig influenza.

A novel use of the known protein erythropoietin (EPO), and / or a derivative, and / or a fragment thereof, is disclosed. EPO is used as a pharmaceutical for the treatment of chronic inflammations. A particularly beneficial result is seen in patients suffering from rheumatoid arthritis (RA). Significant effects are seen in clinical variables such as morning stiffness, swollen joints, and the like.

The invention discloses a compound composition of citral and carvacrol and its application. The combination of citral and carvacrol can inhibit the growth of Clostridium spp, can effectively control the number of Clostridium spp. in the intestinal tract of poultry, and can not only reduce the mortality of broiler chickens with necrotizing enteritis, the score of necrotizing enteritis lesions and the production of caecal contents. The number of Clostridium perfringens can also promote the growth performance of broilers with necrotizing enteritis, increase the average daily feed intake and final body weight, and promote the growth of broilers with necrotizing enteritis. It can be used to prevent necrotizing enteritis caused by Clostridium perfringens infection Enteritis and has a good application prospect.