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34results about How to "Improve disease symptoms" patented technology

Yeast for dietary therapy of diabetes and construction method thereof

The invention describes a yeast for the dietary therapy of diabetes and a construction method thereof. A saccharomyces cerevisiae genome DNA as a template is used for amplifying two sections of rDNA sequences; pYX212 as a template is used for amplifying a nutritional marker gene URA3 and an expression cassette segment driven by a triosephosphate isomerase promoter; the four amplified products are respectively cloned at corresponding loci of pUC18, and thereby an integrating vector pNK1 is obtained. A DNA synthesization point mutation technique is then utilized to remove the restriction sites of dipeptidase VI and trypsin in the natural GLP-1 molecule, so that type I primer segments, type II primer segments and left and right connected filling primer segments are synthesized, and a ten-repeat tandem rolGLP-1 sequence is obtained by the method of step-by-step annealing and one-step connection, and is cloned in the pNK1, so that pNK-GLP is obtained. The pNK-GLP is then linearized, saccharomyces cerevisiae BJ2407 is transformed, and after screening, recombinant yeast SG2 is obtained. Because the rolGLP-1 gene is integrated in yeast chromosome, the recombinant strain can stably and efficiently express the characteristics of the rolGLP-1 and reduce the blood sugar level of a rat with hyperglycaemia, and can be used in the development of yeast biomedicine for treating diabetes.
Owner:NANKAI UNIV

Chinese medicinal oral liquid for smoothing heart and enhancing intelligence

The invention provides a Chinese medicinal oral liquid for smoothing heart and enhancing intelligence. The Chinese medicinal oral liquid is prepared from the following Chinese medicinal raw materials: nutgrass galingale rhizome, cortex eucommiae, rehmannia root, Chinese taxillus twig, large-leaved gentian, twotooth achyranthes root, south dodder seed, turmeric root-tuber, thinleaf milkwort root-bark, bamboo shavings, immature bitter orange, spina date seed, uncaria, dens draconis, bamboo juice, sappan wood, prepared common monkshood daughter root, magnet, common burreed rhizome, peppermint, Chinese ephedra, dragon bone and red date. The Chinese medicinal oral liquid has a good clinical effect on upset major depression patients at every stage, a good treatment effect can be achieved at an administration initial stage, symptoms such as degradation of learning memory, insomnia, early awakening, dreaming, anxiety and the like are relieved, and the pain of patients is relieved greatly; theoral liquid plays a good role for preventing dysphoria of people who are under high working pressure and concentrate intensively every day; and the oral liquid has the outstanding effect of no toxic or side effect, can be used for rapidly improving symptoms of patients, and has the advantages of difficulty in relapsing, low treatment cost, and the like.
Owner:秦建烽

Obesity gene and use thereof

InactiveUS7314713B1Susceptibility to obesityIncreased adipositySugar derivativesMicrobiological testing/measurementGermline mutationDiabetes mellitus
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human obesity and diabetes predisposing gene, specifically the TBC1D1 gene, some mutant alleles of which cause susceptibility to obesity and / or diabetes. More specifically, the invention relates to germline mutations in the TBC1D1 gene and their use in the diagnosis of predisposition to obesity and diabetes. Finally, the invention relates to the screening of the TBC1D1 gene for mutations / alterations, which are useful for diagnosing the predisposition to obesity.
Owner:UNIV OF UTAH RES FOUND

Chinese medicinal oral liquid for smoothing heart and enhancing intelligence

The invention provides a Chinese medicinal oral liquid for smoothing heart and enhancing intelligence. The Chinese medicinal oral liquid is prepared from the following Chinese medicinal raw materials: nutgrass galingale rhizome, cortex eucommiae, rehmannia root, Chinese taxillus twig, large-leaved gentian, twotooth achyranthes root, south dodder seed, turmeric root-tuber, thinleaf milkwort root-bark, bamboo shavings, immature bitter orange, spina date seed, uncaria, dens draconis, bamboo juice, sappan wood, prepared common monkshood daughter root, magnet, common burreed rhizome, peppermint, Chinese ephedra, dragon bone and red date. The Chinese medicinal oral liquid has a good clinical effect on upset major depression patients at every stage, a good treatment effect can be achieved at an administration initial stage, symptoms such as degradation of learning memory, insomnia, early awakening, dreaming, anxiety and the like are relieved, and the pain of patients is relieved greatly; theoral liquid plays a good role for preventing dysphoria of people who are under high working pressure and concentrate intensively every day; and the oral liquid has the outstanding effect of no toxic or side effect, can be used for rapidly improving symptoms of patients, and has the advantages of difficulty in relapsing, low treatment cost, and the like.
Owner:秦建烽

Composition and oral cavity cleaning composition

The invention provides a composition. The composition comprises trehalose and betaine. The invention further provides an oral cavity cleaning composition which comprises trehalose, betaine and auxiliary materials. The oral cavity cleaning composition provided by the invention takes betaine and trehalose as active ingredients, has an antibacterial effect, and can effectively inhibit reproduction of microorganisms in an oral cavity, so that the oral cavity environment is improved; in addition, the composition provided by the invention can also clean the oral cavity, remove tartar, tartar and the like, repair and promote oral mucosa regeneration, and has the effects of preventing tooth decay, improving gingiva and periodontal disease symptoms and the like. Experimental results show that the composition provided by the invention has a good inhibition effect on bacteria and fungi.
Owner:奥俐莱雅(广东)家化科技有限公司
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