The invention provides a method and device for simulating an asynchronous interface, a storage medium and computer equipment, and the method comprises the steps: intercepting an effective calling request with a request address matched with an asynchronous interface address, wherein the asynchronous interface address is a preset address of the asynchronous analog interface; returning a synchronization response to the sender of the effective calling request according to the effective calling request; determining a callback interface address, and determining callback parameters; and when the condition of the callback request is met, sending the callback parameter to a callback interface address, wherein the callback interface address is used for sending an asynchronous response to the senderof the valid call request. According to the method, the MOCK of the asynchronous interface is held, the method is suitable for asynchronous test scenes, and the efficiency in an integrated test containing an asynchronous test can be improved; risks in an integrated test can be preposed, problems can be found and solved in the morning, data waste and unnecessary resource and manpower consumption can be avoided in formal joint debugging, and the cost can be reduced.