51 results about "Treatment hyperthermia" patented technology

A method and device for inducing anaesthesia in mammals by the application of RF energy to create hyperthermia derived neural anaesthesia. An RF generator drives a plurality of electrodes placed in tissue surrounding the target nerve fiber to desiccate the desired length of nerve fiber to be desiccated in a single deployment. The device allows high-speed selection / de-selection of bipolar electrode pairs or sets under continuous RF excitation. Activation of electrode pairs is adapted in response to sensed current density and temperature (by electrodes not in the current discharge activation phase) in order to create lesions of complex and well defined shape necessary for the production of hyperthermia derived neural anaesthesia.

An apparatus for treatment of tissue within a body requiring thermotherapy includes a catheter to be inserted into a bodily conduit, an energy-emitting source disposed within the catheter, a compression balloon surrounding the energy-emitting source where the compression balloon has an inflated diameter that is greater than that of the bodily conduit in a relaxed state and an outside surface of the balloon is coated with one of gene modifiers and drug or medication, and means for activating the energy-emitting source to radiate energy to heat the drug-coated compression balloon and tissue to be treated whereby the heated drug-coated compression balloon effectively delivers the one of the gene modifiers and drug or medication to a target area of the diseased tissue. In addition, methods for using the above apparatus to treat diseased tissue are disclosed.

System method and apparatus for accurately carrying out the in situ heating of a targeted tissue. Small implants are employed with the targeted tissue which exhibit an abrupt change of magnetic permeability at an elected Curie temperature. The permeability state of the implant is monitored utilizing a magnetometer. The implants may be formed as a setpoint temperature determining component combined with a non-magnetic heater component to enhance the tissue heating control of the system. With the system, a very accurate quantum of heat energy can be supplied to a neoplastic lesion or tissue carrying infectious disease so as to maximize the induction of heat shock proteins. The system also may be utilized in conjunction with non-magnetic arterially implanted stents for the hyperthermia therapy treatment of restenosis and in conjunction with the mending of boney tissue.

System method and apparatus for accurately carrying out the in situ heating of a targeted tissue. Small implants are employed with the targeted tissue which exhibit an abrupt change of magnetic permeability at an elected Curie temperature. The permeability state of the implant is monitored utilizing a magnetometer. The implants may be formed as a setpoint temperature determining component combined with a non-magnetic heater component to enhance the tissue heating control of the system. With the system, a very accurate quantum of heat energy can be supplied to a neoplastic lesion or tissue carrying infectious disease so as to maximize the induction of heat shock proteins. The system also may be utilized in conjunction with non-magnetic arterially implanted stents for the hyperthermia therapy treatment of restenosis and in conjunction with the mending of boney tissue.

Methods and systems for delivering electrical energy and controlled, mild hyperthermia to a prostate tissue of a patient for destruction of cancerous and / or hyperplastic tissue. A method includes positioning a plurality of electrodes in a target tissue region comprising the prostate tissue, and establishing an alternating electrical current flow through a volume of the prostate tissue to induce mild heating and destruction of cancerous cells in the volume.

The invention discloses particulates with double functions of internal radiotherapy and thermal therapy, and a preparation method thereof. The particulates are mainly compounded and formed by glass containing radioactive species yttrium-90 or / and phosphorus-32, and solid ferrite with magnetocaloric effect. When the particulates intervene in vivo, the radioactive species yttrium-90 or / and the phosphorus-32 contained in the glass can release Beta rays in vivo to kill cancer cells intervening in surrounding tissues without damaging the distant healthy tissues; the solid ferrite has good hysteresis exothermicity and can transform exosomatic magnetic energy into heat energy so as to release heat under the action of an external alternating magnetic field, so that the temperature around the tumor area can raise to 43 to 47 DEG C within a short time, and tumour cells intervening in the surrounding tissues are burnt and killed without influencing normal cells with better heat tolerance, thereby realizing the purpose of treating tumor by combining the internal radiotherapy and the thermotherapy, and having double lethality to cancer cells. The method for combining the radiation treatment and the heat treatment is an indispensable supplementary therapy means to treat the malignant tumor with chemical drug resistance. In addition, the particulates have good chemical stability and biocompatibility, and have great application prospect in the aspect of treating the malignant tumor.

The present invention relates to a targeted magnetic nanoparticle drug and the preparation method thereof. The targeted magnetic nanoparticle drug comprises an effector molecule and a guidance molecule in a weight ratio of 1:0.0001-0.20. The aforesaid effector molecule is a magnetic particle, with a particle size of not more than 1000 nm and a specific adsorption rate (SAR) of 10-7000 W / gFe. The aforesaid guidance molecule comprises an antibody, a ligand or a magnetic particle. The particle size of the aforesaid targeted drug is 2-1000 nm. The targeted magnetic nanoparticle drug is prepared by coupling a magnetic particle and a guidance molecule in a weight ratio of 1:0.0001-0.20 in water, organic or inorganic substance or the mixed solution thereof. The resultant targeted magnetic nanoparticle drug can realize targeted magnetic hyperthermia treatment and targeted magnetic thermoablation treatment and prevention on the tumors, and effectively kill the cancer cells, and cure the malignant tumors.

A method and composition for hyperthermally treating cells in the eye with simultaneous imaging. The heat (temperature) production inside the eye ( target) tissue is imaged. The desired temperature is achieved using a laser and photoacoustic imaging technique. Hyperthermia treatment of tissue in a target site applies a heat source to kill cells without protein denaturation. The method introduces an encapsulated dye that is released at a selected temperature in the target site to indicate that a threshold temperature has been reached to hyperthermally treat the tissue. In one embodiment, the composition releases the dye at a temperature of 42° C. to 50° C., and preferably about 45° C. to 49° C. The composition which can be a liposome composition encapsulating the dye can be introduced to the bloodstream of the patient to flow through the target site.

Provided are medical apparatuses for simultaneously performing radiotherapy and hyperthermia therapy and methods of treating an affected area. The medical apparatus includes a table where a subject is placed; a driving unit configured to move the table; a treatment device configured to treat an affected area of the subject; and an ultrasonic transducer configured to increase treatment efficiency of the affected area.

System method and apparatus for accurately carrying out the in situ heating of a targeted tissue. Small implants are employed with the targeted tissue which exhibit an abrupt change of magnetic permeability at an elected Curie temperature. The permeability state of the implant is monitored utilizing a magnetometer. The implants may be formed as a setpoint temperature determining component combined with a non-magnetic heater component to enhance the tissue heating control of the system. With the system, a very accurate quantum of heat energy can be supplied to a neoplastic lesion or tissue carrying infectious disease so as to maximize the induction of heat shock proteins. The system also may be utilized in conjunction with non-magnetic arterially implanted stents for the hyperthermia therapy treatment of restenosis and in conjunction with the mending of boney tissue.

The invention discloses a nuclear magnetic resonance compatible cold-thermal therapy system, which comprises a cold therapy module, a thermal therapy module, a heat insulated cold-thermal knife, a temperature sensor and a control module. The cold therapy module and the thermal therapy module are coordinated through a control module to work alternatively, the control module is used for collecting the temperature of focuses during a cold therapy process and the gas pressure in a circuit as well as controlling the flow of gas or liquid in the circuit, and the control module is further used for collecting the temperature of focuses during a thermal therapy process and controlling the heating power. According to a nuclear magnetic resonance cold-thermal therapy system, the growth and melting situations of an ice ball can be monitored in real time, and thus tumour cells can be accurately and rapidly killed.

The invention provides a stone needle thermal therapy new material and application thereof. The stone needle thermal therapy new material is characterized in that a natural stone needle powder body with nanometer fineness is selected and compounded in a conductive material, and the mixture is processed to form the stone needle thermal therapy new material. The material can be processed into various stone needle thermal therapy products, the stone needle thermal therapy material can further achieve the physical therapy effect when the products are used under the condition of heating by external power energy, and the stone needle thermal therapy material not only contains a plurality of microelements, but also has a far-infrared radiation function; and the stone needle thermal therapy material is heated through rubbing to generate ultrasonic pulses (3,698 times / 20-2,000 / hz), can also generate anions and has obvious effects of resisting bacteria, increasing blood oxygen level, removing peculiar smell, losing weight, enlarging chest, and treating neurasthenia, insomnia, scapulohumeral periarthritis, rheumatism, rheumatoid arthritis, amyotrophy caused by chronic nerve diseases and chronic diseases such as tendovaginitis of fingers, wrists and the like which are easily generated for persons who use computers for a long time. The stone needle thermal therapy new material has the characteristics of simple process, wide use, easy purchase of raw materials and low cost.

The invention relates to a superficial tumor ultrasonic thermotherapy system guided by magnetic resonance. The superficial tumor ultrasonic thermotherapy system guided by the magnetic resonance is used to observe and control the temperature of a focus target area of a superficial tumor. The superficial tumor ultrasonic thermotherapy system comprises a main control unit, a power ultrasonic transducer exciting unit, a cooling unit, an ultrasonic transducer, a magnetic resonance imaging (MRI) scanning unit and a MRI temperature processing unit. The main control unit is respectively connected with the power ultrasonic transducer exciting unit, the cooling unit, the MRI scanning unit and the MRI temperature processing unit. The power ultrasonic transducer exciting unit is sequentially connected with the ultrasonic transducer, the focus target area, the MRI scanning unit and the MRI temperature processing unit. The cooling unit is connected with the ultrasonic transducer. The superficial tumor ultrasonic thermotherapy system enables MRI and ultrasonic thermotherapy technology to be combined, so that quantification, real-time and accurate controlling of the therapeutic process of ultrasonic thermotherapy can be achieved. Compared with the prior art, the superficial tumor ultrasonic thermotherapy system guided by the magnetic resonance has the advantages that undamaged, real-time and accurate treatment to the superficial tumor can be achieved, mounting is simple, cost is low and the like.

A method of cancer hyperthermia therapy includes placing a device including an exogenously-excitable polymeric material at a cancer hyperthermia therapy site of a patient. The method also includes supplying an exogenous energy to the device such that the exogenous energy excites the exogenously-excitable polymeric material at the cancer hyperthermia therapy site to heat the cancer hyperthermia therapy site to a hyperthermia temperature. A method of preparing a polymeric material includes combining an alcohol monomer, a seed of the polymeric material, and an aqueous liquid in a vessel. The method also includes adding an acid monomer to the vessel and supplying an exogenous energy to the vessel. The polymeric material is exogenously excited by the exogenous energy to heat the polymeric material. The method further includes removing water from the vessel and producing the polymeric material, which is a polyester, in the vessel.

The invention discloses application of cyclosporin A in drugs in combination with hyperthermia for treatment of a cervical cancer. Combination treatment of the cyclosporine A and thermoexcitation on HeLa cells can significantly induce apoptosis of cancer cells and reduce the survival rate of the cancer cells, thereby achieving the effect of treating tumors, and important ideas are provided for clinical treatment of the tumors.

Disclosed is a medication therapy system for curing nephropathy in a rehabilitation mode through targeted guiding of Chinese herbal medicinal ingredients into a renal region. The system comprises a renal region Chinese herbal medicinal ingredient leading-in instrument, a thermal therapy belt and a drug administration device, the renal region Chinese herbal medicinal ingredient leading-in instrument comprises a controller which can generate an electronic biological wave so as to comprehensively treat human body diseased tissue, the controller can reset output intensity and magnetic thermal therapy temperature to zero automatically and in advance when the renal region Chinese herbal medicinal ingredient leading-in instrument is powered on and control treatment time, treatment mode, output intensity, output frequency, magnetic thermal therapy starting and stopping and magnetic thermal therapy temperature adjustment, when the treatment timing is finished, the instrument is automatically stopped, the thermal therapy belt holds the drug administration device and encircles on the waist of a patient, a drug guiding electrode plate of the thermal therapy belt is communicated with the renal region Chinese herbal medicinal ingredient leading-in instrument through a guide line, and the drug administration device contains the Chinese herbal medicine. By means of the medication therapy system for curing the nephropathy in the rehabilitation mode through targeted guiding of Chinese herbal medicinal ingredients into the renal region, suffering of the patient caused by oral drugs is avoided, the therapeutic effect is good, the treatment cost is low, and a safe, simple, convenient, rapid and painless treatment method is achieved.

With externally applied magnetic fields, we will concentrate in vivo diamagnetic Bismuth particles or unipolar magnetic particles as a confined locus, then push the locus to move to a tumor, shape it to the tumor, then use near IR to heat the particles so to destroy the tumor by thermal ablation or hyperthermia treatment. We will then cause the locus to move to other tumors, and repeat the process, so to destroy all tumors and cure the cancer.

The invention discloses a temperature-controlled vacuum cupping system. The temperature-controlled vacuum cupping system comprises a plurality of temperature-controlled vacuum cups, wherein each temperature-controlled vacuum cup comprises a cup body, a heating element fixing barrel, an electric heating element and a temperature control rod; a vacuum air extracting nozzle connected with a vacuum pumping device is arranged at the rear end of the cup body, and a heating groove and a temperature control groove are concavely formed in the rear end of the cup body; the heating element fixing barrel is arranged in the heating groove in a sleeving way; the electric heating element is arranged at the front part of the heating element fixing barrel, and a heat insulating layer is hermetically packed at the rear part of the heating element fixing barrel; the temperature control rod is arranged in the temperature control groove in a sleeving way, and a temperature sensor and a vacuum pressure sensor are arranged at the front end of the temperature control rod; the temperature sensor, the vacuum pressure sensor, the vacuum pumping device and the electric heating element are respectively connected with a temperature control unit, a vacuum unit, a negative pressure control unit and an electric heating control unit, and the four units are respectively connected with a PC (Personal Computer). The combination work of all the cups can be controlled, and a negative pressure therapy can be combined with a hyperthermia therapy to improve the therapeutic effect of the cupping therapy.

A method and apparatus for treating a condition in a patient such as BPH, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient.

The invention comprises a thermal therapy delivery device for the entire breast and surrounding lactating tissue, including the armpit area, adaptable for delivering thermal therapy to all impacted tissue with either hot or cold therapy. The device also delivers thermal therapy simultaneously to the areas within and surrounding armpit areas and lactation glands and ducts. Other areas treatable simultaneously include radial zones such as the nipple, areola, surrounding glands, lobules, ducts and connective tissue. To accomplish the thermal delivery objectives, the device main components are delineated in zones comprised of individual cells. Each zone treats a distinct anatomical area, and each zone-addressable component has a specific geometry required to effectively deliver thermal therapy to the entire anatomy of the breast.

The invention discloses application of a stone needle in production of health thermo-therapeutic products and a thermo-therapeutic patch. The thermo-therapeutic patch comprises a self-heating component and the stone needle; the stone needle accounts for 5% to 40% of weight of the self-heating component. When the thermos-therapeutic patch releases heat, the temperature peaks in a short time and lasts long; the peak temperature is 50 DEG C to 60 DEG C; therapeutic and health effects are ensured, and scald of the human body caused by excess temperature is never caused; far-infrared 6 micrometers to 14 micrometers in wavelength can be produced during heat releasing, microcirculation can be promoted, and the patch has various health effects.

Methods and systems for delivering electrical energy for controlled heating or hyperthermia to a target tissue of a patient for destruction of cancerous cells or tissue.

The described invention is a hyperthermia and hyperoxygenation medical apparatus for treating diseases of the blood. The general purpose of the invention is three-fold: 1) to provide a medical tool for patient therapy and the treatment of blood viruses and disease organisms by destroying viruses and disease organisms in human and or animal blood and tissues using thermochemical treatment including heat and ozone (O3), and with the potential use of other virus and cancer fighting medications, 2) to provide an active device for hyperoxygenation and hyperthermia of human and animal blood, and 3) to provide a relatively simple treatment method for purifying stored and contaminated blood and blood components or for ensuring the condition of non-contaminated blood and blood components.This invention optimizes and combines the advantages of proven and documented effective hyperthermia and hyperoxygenation medical techniques into a single engineering design for the research and treatment of viruses; certain types of cancers; and stored and contaminated blood supplies. It is an alternative method of specific cancer treatments and applications in diseased blood, gland and organ tissues.

The invention discloses a tumor thermotherapy device based on implanted coils and a parameter optimizing method of a tumor thermotherapy device. Heating magnetic particles need to be injected into a human body in a traditional tumor magnetic mediated thermotherapy, and the thermotherapy effect is reduced when the particles are diffused. The tumor thermotherapy device comprises the in-vivo coil andthe in-vitro coil. The in-vitro coil is an open-loop single-ring circular coil. The in-vivo coil is a closed-loop single-ring circular coil. The radius of the in-vitro coil and the radius of the in-vivo coil are r1 and r2 respectively, and the wire radius of the in-vitro coil and the wire radius of the in-vivo coil are rw1 and rw2 respectively, wherein r1 is equal to the root of r2<2> and d<2>, drepresents the wireless transmission distance, and rw1 is larger than or equal to 1 / 10r1 and smaller than or equal to 1 / 6r1. By means of the device, the sustainable thermotherapy effect can be achieved on tumors.

The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.

The invention relates to a magnet-therapy thermal-therapy massage assembly, and belongs to the technical field of the magnet-therapy thermal-therapy massage device structure. A magnet-therapy thermal-therapy assembly for massage is mounted in an assembly shell, and is characterized in that: a using surface of the assembly shell is a spherical convex massage head for massaging a body; the massage head is internally provided with respectively an infrared light source with an infrared therapeutic effect and a magnet with a magnetic therapeutic effect; and the infrared light source and the exterior of the magnet are respectively covered by a matching protective cover. The magnet-therapy thermal-therapy assembly for massage of the invention is reasonable in structure design and convenient and reliable in use, can be installed in any massage device so as to play the auxiliary massage effect, can also make the massage effect more obvious through the thermal therapy and magnet therapy in the massage process, and is highly practical.

A method for decreasing proliferation of cancer cells comprises the steps of administering a sensitizer. Sensitizers can include selenium, fish oil, and a combination of selenium and fish oil to a cancer cell. The method contemplates that the selenium and fish oil are administered in an amount effective to respectively increase the sensitivity of the cancer cells, and the administration of the combination of selenium and fish oil are administered in an amount effective to synergistically increase the sensitivity of the cancer cells more than the selenium or the fish oil alone. The method additionally exposes cancer cells to temperatures in excess of 37° C.

Devices and methods can be used to deliver thermal therapy to treat tissue. For example, this document provides devices and methods for treating varices, varicosity, other bleeding vessels, polyps, and cancer using microwave-delivered thermal therapy in a minimally invasive fashion. In some embodiment's provided herein, a multidirectional thermal therapy that does not injure surface tissues but causes endothelial injury and coagulation is described. In some implementations, varices are suctioned into a cup that is configured to deliver thermal therapy to the varices, resulting in coagulation.

Precision in thermotherapy is obtained by providing a reverse gelling polymer composition which gels when its temperature is raised above body temperature. The composition is injected into the blood supply of the tissue being treated, at the beginning of thermotherapy. The temperature increase caused by the heating gels the composition, which temporarily blocks the flow of blood in the region being treated. This improves the predictability and stability of treatment. On cessation of heating, the composition liquefies, removing the temporary embolization. The use of local heating can also expedite removal of tumors and the like from soft organs, even when the heating itself has no therapeutic effect.