A method for assessing susceptibility of a subject to a genetically related
disease or condition relative to a general
population. The method includes the steps of: determining the presence or absence of a plurality of risk factors associated with the subject and having a correlation with the
disease or condition; assigning a risk
score, to each of the selected risk factors determined to be present, based upon a strength of correlation assigned to the factor with respect to the
disease or condition; and combining the risk scores to calculate an overall susceptibility
score, wherein the overall susceptibility
score represents susceptibility of the subject to the disease or condition in relation to a base score representing the risk that a member of the general
population will have the disease or condition without consideration of risk factors. The risk factors require the inclusion of at least two of age, gender, race, and family history and require the inclusion of a plurality of polymorphisms selected for known correlation with the disease or condition.