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167 results about "Polymeric microspheres" patented technology

Polymeric Microspheres As Degradable Fluid Loss Additives In Oilfield Applications

Methods and apparatus for forming a fluid for use within in a subterranean formation including crosslinking a polymer along the surface of microspheres in a water-in-water emulsion and introducing the microspheres into the subterranean formation. Methods and apparatus for forming a fluid for use within in a subterranean formation including crosslinking a polymer along the surface of microspheres in a water in water emulsion, isolating the microspheres from the emulsion, and introducing the microspheres into the subterranean formation. Methods and apparatus for forming a fluid to treat a subterranean formation including introducing a crosslinkable polymer, partitioning agent, and crosslinker into a solvent, crosslinking the crosslinkable polymer, isolating beads of the crosslinkable polymer from the partitioning agent, introducing the beads into a fluid for treating a subterranean formation.
Owner:SCHLUMBERGER TECH CORP

Method for preparing microspheres and microspheres produced thereby

The present invention relates to a method for preparing microsphere and microspheres produced thereby. The method comprises: mixing a water-insoluble organic solvent with a dispersion solvent; mixing a polymer compound, a drug and a water-insoluble organic solvent to prepare a dispersed phase; mixing the dispersed phase with the dispersion solvent mixed with the water-insoluble organic solvent to prepare an emulsion; and adding a base or an acid to the prepared emulsion. With the method, it is possible to prepare a drug-containing polymeric microsphere cost-effectively and conveniently.
Owner:SK CHEM CO LTD +1

Preparation method of molecularly imprinted polymeric microspheres for 2,4,6-trinitrophenol detection

The invention discloses a preparation method of molecularly imprinted polymeric microspheres for 2,4,6-trinitrophenol detection. The preparation method is characterized in that polynitrophenol derivatives-imprinted molecules generated through reaction between 2,4,6-trinitrophenol and N,N'-diisopropyl carbodiimide have luminous yellow fluorescent light, the fluorescent light of the imprinted molecules has open and close characteristics under an acid-base condition, the imprinted molecules located in an imprinting layer of the molecularly imprinted polymeric microspheres can be eluted, a hole structure which is complementary with the structure, the size and the functional groups of the imprinted molecules is formed in the imprinting layer, polymeric microspheres of which the imprinted molecules are eluted have specific recognition sites on target analyte molecules, target molecules enter the specific recognition sites, selective recognition on the target analyte molecules is realized, sensitivity detection of the target analyte molecules can be realized through opening and closing of the fluorescent light of the target molecules, the specific surface area of the molecularly imprintedmicrospheres is large, and space in which the recognition sites are formed is stable in structure, has more effective sites, and is capable of carrying out high-selective recognition and high-sensitive detection on the target molecules.
Owner:霍尔姆斯(北京)生物科技有限公司

Method for producing microspheres loaded with drugs and microspheres loaded with drugs produced thereby

The present invention relates to a method for producing polymeric microspheres loaded with drugs and polymeric microspheres loaded with drugs produced thereby, specifically a method for producing polymeric microspheres loaded with drugs, the method comprising the steps of a) adding a dispersion phase containing a high molecular compound, a drug, and a water-insoluble organic solvent to a dispersion solvent to produce an O / W (oil-in-water) type or 0 / 0 (oil-in-oil) type emulsion, or adding a W / O (water-in-oil) type emulsion, which is prepared by emulsifying an aqueous solution, in which a drug is dissolved, in a water-insoluble organic solvent, in which the high molecular compound is dissolved, to the dispersion solvent to produce a W / O / W (water-in-oil-in-water) type emulsion; and b) adding an ammonia solution to the emulsion produced in step a) to convert the water-insoluble organic solvent into water-soluble solvents, and polymeric microspheres loaded with drugs produced thereby. According to the present invention, the desired polymeric microspheres loaded with drugs can be simply produced with a small amount of water in a short period of time.
Owner:SK CHEM CO LTD +1

Carrier for immobilizing enzyme, use thereof, and carrier immobilized with enzyme

The invention relates to a novel carrier with good permeability for immobilizing enzymes. The carrier is a polymer microsphere not only with small and medium pores smaller than 90nm, but also with large pores of hundreds of nanometers. The carrier can be used for both single-enzyme immobilization and multiple-enzyme immobilization. The utilization rate of the microsphere surface can reach 70%-100%. The present invention also relates to the use of the carrier for immobilizing enzymes in immobilizing enzymes and the carrier immobilized with enzymes. Because the enzyme can be immobilized inside the carrier and can be well protected by the carrier, it has good stability, activity and reusability, and is especially suitable for column packing for continuous reactions.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI

Cyclodextrin cross-linking polymeric microsphere capable of absorbing bilirubin and its preparation and application

The present invention relates to the removal of bilirubin from blood, and is especially cyclodextrin crossed polymer microsphere for adsorbing bilirubin and its preparation and application. The microsphere is prepared with diisocyanate as crosslinking agent and through condensation with cyclodextrin monomer. The polymer microsphere of the present invention has low cost and results in simplified experiment process, and the efficient removal of bilirubin with the polymer microsphere shows that the said material has excellent clinical application latent.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Laminated steel with compliant viscoelastic core

Laminated metallic sheets which comprise an interior layer of a viscoelastic polymeric compound sandwiched between outer layers of metallic sheet may exhibit enhanced properties through modification of the viscoelastic phase. In a first embodiment the elastic modulus of the viscoelastic polymeric compound may be reduced by incorporating voids, bubbles or pores within the compound. These voids which may be introduced by introduction of polymeric microspheres are effective in reducing the internal stresses induced in the laminate by temperature changes. In a second embodiment, coating the microspheres with an electrically-conductive layer may be effective in enabling resistance spot welding of such laminated materials.
Owner:GM GLOBAL TECH OPERATIONS LLC

Multiwall polymeric microcapsules from hydrophilic polymers

Two or more hydrophilic polymers that are not soluble in each other at a particular concentration and temperature, but which have a positive spreading coefficient in solution, are used to form multi-layered polymeric microspheres. The multi-layer microspheres produced by the method are distinguished by extremely uniform dimensioned polymer layers and actual incorporation of a substance to be delivered into the polymer layers. In the preferred embodiment of the method, two polymers are dissolved in an aqueous solvent, the substance to be incorporated is dispersed or dissolved in the polymer solution, the mixture is suspended in an organic solvent or polymer / water mixture and stirred, and the solvent is slowly evaporated, creating microspheres with an inner core formed by one polymer and an outer layer formed by the second polymer.
Owner:BROWN UNIV RES FOUND INC

Graphene oxide-polymeric microsphere water-based lubricant additive and preparation method thereof

The invention belongs to the field of lubricant additives, and particularly relates to a graphene oxide-polymeric microsphere water-based lubricant additive as well as a preparation method of the lubricant additive. The preparation method comprises the following steps: preparing graphene oxide powder and a polymeric microsphere emulsion, wherein the polymeric microsphere emulsion is the polyacrylate microsphere emulsion or polystyrene microsphere emulsion; adding the graphene oxide powder into the polymeric microsphere emulsion, conducting ultrasonic vibration until the graphene oxide powder is completely dispersed to obtain a graphene oxide-polymeric microsphere compound emulsion, and diluting the graphene oxide-polymeric microsphere compound emulsion to be with the mass fraction of 0.1-2% through the deionized water, so as to obtain the graphene oxide-polymeric microsphere water-based lubricant additive. The graphene oxide-polymeric microsphere water-based lubricant additive is adopted to replace the conventional oil-based lubricant, so that the friction coefficient can be reduced, the abrasion resistance can be improved, the environmental pollution can be reduced, the cost can be reduced, the use stability can be improved, and meanwhile, various efficacies of cooling, rust prevention, corrosion inhibition and the like can be achieved.
Owner:WUHAN UNIV OF TECH

Method for preparing polymeric microsphere by aqueous two phase emulsion process

A method for preparing polymeric microsphere by an aqueous two phase emulsion process. A first polymer aqueous solution is provided and the first polymer includes a functional group capable of forming cross-linking. A second polymer aqueous solution is provided, which is acidic and miscible with the first polymer aqueous solution. The first and second polymer aqueous solutions are mixed and stirred to form an emulsion, such that the first polymer solution forms a dispersed phase in a continuous phase of the second polymer solution. The dispersed phase includes a plurality of the first polymeric microsphere, and a solidification film formed by cross-linking of the functional group constitutes a microsphere surface. Finally, the first polymeric microsphere are separated out.
Owner:IND TECH RES INST

Multiple efficacy complex microsphere for cosmetics and preparation method thereof

The invention discloses a multifunctional composite microsphere for cosmetics and a preparation method thereof. The multifunctional composite microsphere for cosmetics is a porous inorganic / polymer composite microsphere formed by using polymer porous microspheres as mother particles and nano-inorganic particles as daughter particles, and the daughter particles are evenly dispersed and bonded to the surface of the mother particle. During preparation, polymer porous microspheres and solvents are prepared into a suspension, and then nano-inorganic particles treated with a silane coupling agent are added to the suspension, kept at a constant temperature of 30-100°C, stirred and refluxed at a high speed, and the inorganic / polymerized porous composite microspheres. The invention solves the problem that the particle size of nano inorganic particles used in cosmetics is too fine to agglomerate and block pores, and at the same time, its porous structure can carry cosmetic active substances with different functions, so as to achieve multi-component coexistence and slow release and controlled release. Compared with other sustained-release microspheres, the composite microsphere has a photoprotective effect on the cosmetic active substances easily oxidized inside, and the sustained-release performance is increased by more than three times.
Owner:SOUTH CHINA UNIV OF TECH

Array structure fabric surface and preparing method and application thereof

The invention provides an array structure fabric surface and a preparing method and application thereof. According to the preparing method for a conical array structure fabric surface, the surface of a semiconductor substrate is paved with a single polymeric microsphere thin film layer, a pillar array structure is etched on the surface of the semiconductor substrate with the polymeric microsphere as a protection layer, a foundation pillar in the semiconductor substrate is oxidized, and an oxidation layer is removed to obtain the fabric surface of a conical array structure. The specific surface area of the fabric surface of the conical array structure manufactured through the method is small, the surface recombination possibility of a photon-generated carrier is low, the preparing technology of the array structure fabric structure is simple, a template is not needed, cost is low, and the defects that in the prior art, large-scale generation cannot be achieved, the preparing steps are complex, and cost is high are overcome.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI

Preparation method of photonic crystal with inverse opal structure

The invention discloses a preparation method of a photonic crystal with an inverse opal structure, and belongs to the technical field of the photonic crystal with the inverse opal structure. The preparation method comprises the following technological steps of: firstly adding polymeric microspheres to colloidal sol in proportions, and then dispersing the mixture for 10-60 minutes by using ultrasonic waves so as to form a uniform stable suspension emulsion; transferring the prepared suspended emulsion to a glass container, and vertically placing a clean substrate in the glass container filled with the suspended emulsion; then slantwise placing the glass container on a heating platform, and heating so as to volatilize a solvent; utilizing a binary synergistic effect for ensuring that polymeric microspheres and the colloidal sol grow on the substrate in a self-organizing manner to form a polymer; after ending growth, taking out a sample, and heating in air under an appropriate temperature condition so as to decompose and volatize the polymer; cooling and taking the sample to obtain the photonic crystal with the inverse opal structure, which has good degree of crystallinity and no defects and is large in area.
Owner:ADVANCED TECHNOLOGY & MATERIALS CO LTD

Water injection well multi-slug profile control method

The invention provides a water injection well multi-slug profile control method. A multi-slug injection method is adopted, wherein a first slug adopts an organic jelly glue aqueous solution system including volume expansion grains; and a last slug comprises two stages, the first stage adopts an organic jelly glue aqueous solution system including volume expansion grains, and a profile control agent adopted by the second stage is a microsphere deep profile control modifying and flooding agent. In the water injection well multi-slug profile control method, a jelly glue type profile control agent selected and used by the first slug can form a powerful 'baffle' at the well bottom water injection front end, and the phenomena that a medicament is subsequently injected, and oily sludge directly dashes into an extraction oil well are avoided. In the last slug, the sizes of micro hole passageways are reduced through expansion performance of polymeric microspheres, depressurization and augmented injection are conducted through adsorbability of the polymeric microspheres, and well group oil production is increased through displacement performance of the polymeric microspheres. In the injection method adopting the three slugs, while consuming the oily sludge in a massive dose mode, the second slug enters large hole passageways and cracks to block a high-permeability layer band.
Owner:SHAANXI HEZHUN ENERGY SCI & TECH CO LTD

Preparation method of honeycombed graphene/tungsten carbide/platinum composite electrocatalyst and application thereof

The invention belongs to the technical field of electrocatalyst preparation and specifically discloses a preparation method of a honeycombed graphene / tungsten carbide / platinum composite electrocatalyst and its application. By the adoption of a spherical template and by a high-temperature reduction method, a honeycombed ''graphene / tungsten carbide'' complex is prepared by one step. The spherical template is used as a support to load tungsten carbide and graphene onto the surface of the spherical template. As some polymeric microspheres which are rich in a carbon source and are easy for pyrolysis are selected and the spherical template is decomposed during high temperature reduction process to release carbonaceous gas, the carbonaceous gas can react with the tungsten source so as to generate honeycombed graphene / WC with ultrafine partical size. Meanwhile, the spherical template is automatically decomposed and disappears during the high temperature process. Thus, no additional step of eliminating the template is required. The three-dimensional honeycombed ''graphene / tungsten carbide'' complex has higher specific surface area, stronger conductivity and stability. The invention provides new development strategies for development of the high-performance WC-based synergistic ''low-platinum electrocatalyst''.
Owner:GUANGDONG UNIV OF PETROCHEMICAL TECH

Method for preparing half-strawberry type Janus particle

The invention relates to a method for preparing a half-strawberry type Janus particle. The method comprises the steps of: by taking a large-grain-size modified silicon dioxide microsphere as a core microsphere and taking a small-grain-size silicon dioxide or polymeric microsphere as a crown microsphere, using a Pickering emulsion method to modify the modified silicon dioxide microsphere into an initial Janus particle, and self-assembling with the crown microsphere by using the interaction between each function to obtain the half-strawberry type Janus particle. The preparation method has the characteristics of simple equipment and controllable operation, the product is pure, monodisperse and uniform in aperture. Compared with a common method, the method for preparing the half-strawberry type Janus particle has the advantages of controllable operation and simple method and is capable of preparing a complex Janus particle.
Owner:TIANJIN POLYTECHNIC UNIV

Method for preparing polymeric microspheres and polymeric microspheres produced thereby

The present invention relates to a method for preparing polymeric microspheres and polymeric microspheres produced thereby. More particularly, the present invention relates to a method for preparing a polymeric microsphere comprising the steps of: mixing a water-insoluble organic solvent with a dispersion solvent; mixing a polymer compound, a drug and a water-insoluble organic solvent so as to prepare a dispersed phase; mixing the dispersed phase with the dispersion solvent mixed with the water-insoluble organic solvent so as to prepare an emulsion; and adding a base or an acid to the prepared emulsion so as to remove the water-insoluble organic solvent from the emulsion and a polymeric microsphere thereby, and a composition for drug delivery comprising the microspheres. The invention provides the new polymeric microsphere preparation method by removing water-insoluable organic solvents from emulsions by using base or acids, the polymeric microspheres prepared by the prepration method, and the composition for drug delivery comprising the polymeric microspheres. Therefore, the preparation method of the invention is different from original solvent evaporation or solvent extraction procedures, realizes minimization of waste water generation by using less water, and simply prepares target durg-containing polymeric microspheres within a short period.
Owner:SK CHEM CO LTD +1

Preparation method of conductive polymer film having inverse opal structure

The invention discloses a preparation method of a conductive polymer film having an inverse opal structure. The preparation method comprises that an electrochemical polymerization reaction occurs based on polymeric microspheres (comprising polystyrene microspheres or amino-polystyrene microspheres) as templates, and then the conductive polymer film having an inverse opal structure is obtained by impurity removal treatment and polymeric microsphere removal treatment. The preparation method has simple processes, utilizes the polymeric microspheres as hard templates, and can be carried out at a room temperature without harsh reaction conditions. The prepared conductive polymer film having an inverse opal structure has tidy morphology and good structural environment stability.
Owner:ZHEJIANG UNIV OF TECH

Process and systems for the efficient production of polymeric microspheres

Processes and systems are provided whereby continuous polymeric microspheres are made by nebulizing a solventless initiated monomeric liquid (that is a liquid solution comprising a monomer and a polymerization initiator for the monomer) to form an aerosol of polymerization-initiated monomeric liquid droplets within a gas-filled reaction zone. The nebulized droplets of the monomeric liquid are allowed to fall under gravitational force through the reaction zone and to polymerize therewithin. The thus polymerized particles may thereafter be collected and removed from the reaction zone for further processing and / or use as may be desired.
Owner:LUNA INNOVATIONS

Degradable polymer microspheres and preparing method thereof

PendingCN108047464AAvoid stickingImprove dimensional uniformityPolymer scienceOrganic solvent
The invention provides degradable polymer microspheres and a preparing method thereof. According to the characteristics of a micro flow method, a thin pipe is used in an emulsifying-curing method forpre-limiting the size of organic phases, and the organic phases are rapidly cut into microspheres of the preset size when being slowly injected into a large quantity of water phases. Organic solvent in the micron-level polymeric microspheres can be rapidly diffused into the water phases, and adhesion between the polymeric microspheres in the later period is avoided. According to the preparing method, the uniformity of the size of microspheres obtained with the traditional emulsifying-curing method is improved, the quality of the polymeric microspheres is improved, and the yield of the polymeric microspheres is increased. According to the preparing method for simply and rapidly preparing the degradable polymer microspheres with high uniformity, by deploying various technical parameters in the microsphere preparing process, the prepared microspheres are uniform in particle size distribution, the distribution coefficient of the diameter is 25% or below, and compared with particle size distribution of the microspheres prepared with a conventional multiple-emulsion method, the remarkable significance is achieved.
Owner:深圳市博立生物材料有限公司

Process for producing platinum metal nano-particle for catalysis with polymer microsphere as carrier

The invention relates to a preparation method of catalytic platinum metal nano particles using polymeric microspheres as a carrier, pertaining to technological field of polymer material and metal nano catalytic material. The invention can synthesize a special type of terpolymer polymeric microspheres of polyamide macro-molecular monomer ingrafted acrylonitrile / styrene through dispersion copolymerization; the catalyst can utilize soluble platinic acid as a source of platinum, and in-situ reduce platinum metal ions into platinum atoms on the surfaces of polymeric microspheres through the complexation reaction between platinum metal ion and a acidamide group, while the acidamide group is located at a hydrophilic polyamide long train of the surface of polymeric microspheres; the polymeric microspheres can be continuously grown and form into stable platinum metal nano particles using polymeric microspheres as the carrier, with the platinum particle diameter be controlled between 2 to 50nm and uniformly dispersed on the surfaces of the polymeric microspheres. The preparation process of the invention has moderate reaction conditions, simply and easily carried method, and the prepared platinum metal nano particles can be used as the catalyst of various chemical reaction.
Owner:JIANGNAN UNIV

Indepth fluid diverting agent of oil reservoir and preparation method and application of indepth fluid diverting agent

The invention provides an indepth fluid diverting agent of an oil reservoir and a preparation method and application of the indepth fluid diverting agent. The indepth fluid diverting agent comprises, by mass, 20-35wt% of acrylamide based monomers, 2-10wt% of vinyl-containing silane, 10-25wt% of arene-containing vinyl or olefine monomers, 0.03-0.1wt% of a cross-linking agent, 0.02-0.08wt% of an initiating agent, 0.5-2wt% of a dispersing agent, 2-12wt% of an anti-sticking agent, and the balance water. The invention further provides the preparation method of the indepth fluid diverting agent. The preparation method includes the steps that the acrylamide based monomers, the vinyl-containing silane, and the arene-containing vinyl or olefine monomers are mixed and then heated to 60-80 DEG C, the cross-linking agent, the initiating agent, and the dispersing agent are added, after 1-2 hours of reaction, the anti-sticking agent is added, after polymeric microsphere suspension is formed, precipitation separation is conducted, and the indepth fluid diverting agent of the oil reservoir is obtained. In addition, the invention provides the application of the indepth fluid diverting agent in profile control and oil displacement of a water injection well.
Owner:PETROCHINA CO LTD

Superpara magnetism polymeric microsphere magnetic resonance imaging (MRI) contrast agent and preparation method thereof

The invention discloses a superpara magnetism polymeric microsphere magnetic resonance imaging (MRI) contrast agent and a preparation method of the superpara magnetism polymeric microsphere MRI contrast agent, and relates to the MRI contrast agent used for diagnosis and treatment and the preparation method of the MRI contrast agent used for the diagnosis and the treatment. Polymeric microspheres are formed by polymerizable amphiphilic macromolecules, styrene monomers and Fe3O4 nano particles in a one-time batch feeding polymerization mode. Each microsphere comprises a core-shell structure, an inner core envelopes the superpara magnetism Fe3O4 particles, and a shell layer surface contains abundant functional groups. The microspheres are enabled to have targeting functions through coupling targeting molecules, and suitable for targeting MRI for certain diseases. The superpara magnetism polymeric microspheres are simple in synthetic process, low in preparation cost, controllable in microsphere particle diameter, stable in form, good in biocompatibility (BC) and MRI effect, and good in popularization and application values.
Owner:XIAMEN UNIV

Thermosensitive bisphenol A (BPA) imprinted polymeric microsphere and application thereof

The invention belongs to the field of material sciences and engineering and environmental sciences and particularly relates to a thermosensitive bisphenol A (BPA) imprinted polymeric microsphere and application of the thermosensitive BPA imprinted polymeric microsphere. According to the thermosensitive BPA imprinted polymeric microsphere, polystyrene is used as a carrier, BPA is used as template molecules in combination with thermosensitive material monomers, and the temperature-responsive BPA imprinted polymeric microsphere is obtained through polymerization. The thermosensitive BPA imprinted polymeric microsphere is used for detection of the BPA. The thermosensitive BPA imprinted polymeric microsphere is clear in principle, novel in design, low in cost and easy and convenient to operate; the imprinted polymeric microsphere obtained through dispersion polymerization, swelling polymerization, precipitation polymerization and other methods is regular in morphology, stable in nature, capable of adsorbing the BPA quickly, high in bonding capacity, good in specificity and reproductibility, capable of achieving the standard recovery rate of more than 90% when applied to detection of sea water or yoghourt samples containing the BPA, and good in reuse performance; besides, the obtained intelligent imprinted polymers are sensitive in response to external temperatures, and different temperatures of solutions have a great influence on the adsorption capacity of the thermosensitive BPA imprinted polymeric microsphere.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI

Polymer microspheres containing latent colorants and method of preparation

InactiveUS20050020786A1Excessive “background noise”Increase loadMulticolor photographic processingPaper coatingSolventColoring agents
The present invention relates to a polymer microsphere comprising at least one polymer and at least one bound latent colorant, wherein the microsphere is stabilized by at least one stabilizing polymer. The invention also includes a method of preparing polymer microspheres comprising combining latent colorant, ethylenically unsaturated monomer, stabilizing polymer, and an initiator in solvent and initiating polymerization to form a polymeric microsphere stabilized by a stabilizing polymer bound to the surface of the polymeric microsphere.
Owner:EASTMAN KODAK CO
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