The invention belongs to the technical field of traditional Chinese medicines and particularly provides a plaster for treating ulcer of lower limbs. The plaster for treating the ulcer of the lower limbs is prepared from angelica roots, pangolins, honeysuckles, a barbed skullcap herb, radix angelicae sinensis, radix rehmanniae, garden balsam stems, radix sileris, gallnuts, fructus forsythiae, stiff silkworms, peach kernels, cassia twigs, Chinese honeylocust spine, radix cyathulae, folium artemisiae argyi, long pepper, radix bupleuri, frankincense, myrrh, calomel, dragon's blood, camphor, borneol, musk, minium and sesame oil. The plaster follows the theory of 'removing necrotic tissues to promote tissue regeneration and removing pus to promote tissue regeneration' of Chinese medicine, enables the Chinese herbal medicines to be externally coated on affected parts, makes the medicine effects act on the local parts, conditions the oxygen tension of the affected parts and angiogenesis, facilitates dissolution of necrotic tissues and fibrous protein, promotes release of multiple growth factors and further achieves the purposes of relieving pain and accelerating wound healing, and clinical trials show that the plaster is remarkable in curative effect, economic, practical, free of side effects and worthy of clinical popularization and application.