The invention relates to a natural green biology organic pesticide composition and use thereof, wherein the technique features are: A producing natural biology pesticide using natural camphor, rhubarb, cinnamon, oleum eucalypti, ginger, common fennel, red pepper and auxiliary material; B producing natural biology pesticide using atractylodes rhizome,magnolia bark (prepared with ginger), tuckahoe,dried pinellia, patchouli oil, dried old orange peel, dahurian angelica root, areca peel, licorice extract, purple operilla leaf oil and auxiliary material. The pesticide can be directed applied on melon type, fruit type, leaf type vegetables, leguminous vegetables, tea leaf, traditional Chinese medicinal material, flower, fruit, rape, cotton, tobacco to control the pest. The vegetable and fruit using the biology organic pesticide can be directly eaten without residual pesticide harm to human.