143 results about "Multi-component reaction" patented technology

A mod of combustion and a multi-component reactor to accomplish this mode of combustion are disclosed which produces fullerenes and fullerenic material by combustion. This mode consists of de-coupling an oxidation region of a flame from a post-flame region, thus giving greater control over operating parameters, such as equivalence ratio, temperature, and pressure; allows conditions of the operating parameters of the combustion reaction to be attained which would not be easily attained by conventional methods; and offers the ability to more easily stabilize the combustion reactions to allow for higher throughputs of fuel and oxidant. Several embodiments of a primary zone of a multicomponent reactor are also disclosed. Said primary zone serves as the oxidation region, operates on the principle of providing recycle to the reacting combustion mixture, and which may be operated as approximately a well-mixed reactor. A secondary zone is also disclosed which provides further residence time for reaction and the ability to control operating parameters, operates on the principle of minimizing recycle of the reacting combustion mixture. The secondary zone may be operated as approximately a plug-flow reactor. The primary and secondary zones may be operated in conjunction or either one alone.

A new class of imidazolines as 4-position esters with very potent anti-inflammatory as well as antimicrobial activity is described. The synthesis of these imidazolines includes a multicomponent reaction applicable to a combinatorial synthetic approach. The combination of these two key characteristics provides an effective therapeutic drug in the treatment of septic shock as well as many other inflammatory (arthritis and asthma) and infectious disorders. The use of this novel class of non-steroidal agents as anti-inflammatory agents (for the treatment of asthma, etc.), antibacterial agents, and antiseptic agents is described. The compounds are also useful in the treatment of tumors (such as cancers). The imidazolines are potent inhibitors of the transcription factor NF-κB as well as potent activity against the Gram (+) bacterium. The compositions are also useful for treating autoimmune diseases and for inhibiting rejection of organ and tissue transplants.

The invention relates to a polishing pad, a polyurethane polishing layer and a preparation method thereof, and belongs to the field of a polishing technology for chemical mechanical planarization processing. The polyurethane polishing layer with the coefficient of thermal expansion being 70 to 200ppm / DEG C contains a reaction product generated by multi-component reaction. The multiple components comprise an isocyanate end-capped prepolymer, a hollow microporous polymer and a curing agent composition. The curing agent composition comprises 5-55 weight percent of aliphatic diamine composition, 0-8 weight percent of polyamine composition, and 40-90 weight percent of aromatic bifunctional composition. The polyurethane polishing layer has the density being 0.6- 1.1g / cm<3>, the shore harness being 45-70 D, and the elongation at break being 50-450 percent. A preparation process of the polyurethane polishing layer is simple, low in cost and small in energy consumption, and the polyurethane polishing layer prepared through the process has the advantages of high hydrolytic stability, uniform density, stable removal rate and the like.

The invention belongs to the technical field of preparation of pharmaceutical intermediates, and concretely relates to a new method for preparing an indolyl spirocyclic compound through an iodine catalyzed multi-component reaction. An isatin derivative, a 1,3-dicarbonyl compound, and 4-hydroxycoumarin and a derivative thereof are used as raw materials, and iodine is used as a catalyst, so the method has the advantages of easiness in obtaining of the raw materials, and simple reaction operation, and the generated compound product can be used as a candidate drug, and has potential application values.

A new class of imidazolines as 4-position acids or esters with very potent anti-inflammatory as well as antimicrobial activity is described. The synthesis of these imidazolines includes a multicomponent reaction applicable to a combinatorial synthetic approach. The combination of these two key characteristics provides an effective therapeutic drug in the treatment of septic shock as well as many other inflammatory (arthritis and asthma) and infectious disorders. The use of this novel class of non-steroidal agents as anti-inflammatory agents (for the treatment of asthma, etc.), antibacterial agents, and antiseptic agents is described. The compounds are also useful in the treatment of tumors (such as cancers). The imidazolines are potent inhibitors of the transcription factor NF-κB as well as potent activity against the Gram (+) bacterium. The compositions are also useful for treating autoimmune diseases and for inhibiting rejection of organ and tissue transplants.