854 results about "Lipid blood" patented technology

A method and composition for blood lipid therapy by administering to the subject an effective amount of a dyslipidemic agent and omega-3 fatty acids. The method utilizes a single administration or a unit dosage of a combination of dyslipidemic agent and omega-3 fatty acids for the treatment of patients with hypertriglyceridemia, hypercholesterolemia, mixed dyslipidemia, coronary heart disease (CHD), vascular disease, artherosclerotic disease and related conditions, and the prevention or reduction of cardiovascular and vascular events.

The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and / or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.

Methods for assessing the risk of developing Type 2 diabetes and other related disorders include obtaining an NMR derived reference spectrum for a known glucose concentration sample and storing this information as a reference standard. A patient blood sample is collected and NMR derived patient spectrums for the blood sample are obtained. The two NMR data sets (the reference and the patient) are compared and a glucose concentration is determined for the patient sample. The glucose concentration can be evaluated with a blood sample undergoing lipoprotein cholesterol evaluation. The NMR based test can be used to concurrently provide a glucose concentration and lipoprotein constituent values based on a single testing event. The disclosure also includes a multi-purpose test, i.e., a test which concurrently provides lipoprotein screening and coronary heart disease risk evaluation along with a diabetes screening and risk assessment for developing Type 2 diabetes. A method for assessing diabetes includes identifying the presence of diabetic dyslipidemia based on the values of predetermined NMR measured lipoprotein constituents.

The invention provides a black soybean cake processing method. The processing comprises the steps that 1, black soybean powder, glutinous rice flour, rice flour, red dates, lily, sweet-scented osmanthus, the fruits of Chinese wolfberry, mint leaves, granulated sugar, sesame powder and palm oil are weighed; 2, the red dates, the lily, the sweet-scented osmanthus, the fruits of Chinese wolfberry and the mint leaves are heated and decocted; 3, the granulated sugar is heated to be dissolved; 4, the black soybean powder, the glutinous rice flour and the rice flour are mixed, and then mixed liquid and the palm oil are added in the mixture for high-temperature steaming; 5, the steamed cake is coated with the sesame powder in a rolling mode. The black soybean cake processing method has simple steps, the black soybean cake is crisp and delicious and makes people enjoy aftertaste, and black soybeans have rich nutrients and have the effects of promoting cholesterol metabolism, lowering blood lipid, preventing cardiovascular disease and the like. Meanwhile, due to the fact that the red dates, the lily, the sweet-scented osmanthus, the fruits of Chinese wolfberry, the mint leaves and the like are added in the formula, the black soybean cake has the effects of enriching yin, nourishing kidney, protecting the liver, nourishing the stomach, discharging toxicant, keeping beauty and the like.

The invention relates to a production process of chewable tablets of barley shoot powder and a product thereof and belongs to the deep processing technology field of agricultural products. The production process is characterized in that the barley shoot powder is main base material, and the chewable tablets of the barley shoot powder with smooth appearance, green color and crispness and freshness is made after the processes of composite stabilizer, making soft material, granulation, drying, tabletting, sterilization and packing. The method has the advantages of simple process, higher industrialization degree, low production cost, realizing the full utilization of the barley shoot and promoting the added value of the barley shoot. The chewable tablets of the barley shoot powder produced by the invention which is leisure-base health care food can fully enhance physique and body immune, simultaneously has the function of catharsis, reducing blood lipid and preventing cerebral thrombosis and coronary heart disease.

Combination therapy comprising the administration of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent useful for treating, preventing and reducing the risk of developing insulin resistance, dyslipidemia, obesity, hypertension and other related diseases and disorders.

The present invention provides pharmacological interventions for the treatment of dyslipidemia, and to the reduction of residual risk of cardiovascular disease and adverse cardiovascular events in patients on intense statin use or with well-controlled LDL-C concentrations. In particular, the invention relates to the use of pemafibrate to prevent cardiovascular events in populations at-risk due to risk factors such as type 2 diabetes mellitus with dyslipidemia in spite of intense statin use or well-controlled LDL-C.

Techniques for managing diabetes and pre-diabetes using light are disclosed herein. In one example, a light generating device is positioned to a body part of a diabetic or pre-diabetic patient, and a beam of light generated by the light generating device is directed to the body part of the patient to control blood sugar level of the patient. In various embodiments, the beam of light directed to the patient can also help to control the blood lipid level such as triglyceride level, blood liver enzyme of the patient, and various other symptoms of diabetes and pre-diabetes. In various embodiments, the body part includes body area rich in adipose tissue, such as the abdominal area, thigh, buttocks, and upper arms of the patient.

A class of benzopyrancarboxylic acid derivatives comprises compounds that are potent agonists of PPAR alpha and / or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and / or gamma mediated diseases, disorders and conditions.

The present invention relates to novel dihydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

A class of benzopyrancarboxylic acid derivatives comprises compounds that are potent agonists of PPAR alpha and / or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and / or gamma mediated diseases, disorders and conditions.

Methods of treating metabolic diseases and disorders using a FGF21 polypeptide are provided. In various embodiments the metabolic disease or disorder is type 1 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, diabetic nephropathy, neuropathy, retinopathy, ischemic heart disease, peripheral vascular disease and cerebrovascular disease

The invention discloses a balsam pear extract and preparation thereof. The extract liquid is made from extraction using fruit of cucurbit balsam pear as raw material. The extraction process includes using water as the solvent, and extracting the balsam pear extract liquid by zymohydrolysis, ultrasonic processing or the like. The balsam pear extract liquid is in light yellow or yellow, contains active substance such as balsam pear saponins, balsam pear polypeptides and active polysaccharide. The process is simple and fast, easy for industrial production, with nutritious extract, without environment pollution, and having low cost. The balsam pear extract has evident function of blood glucose and blood lipid lowering.

The invention discloses nutritional health-care fine dried noodles which are developed with suaeda salsa, stigma maydis and Chinese herbal medicines such as the root of kudzu vine, gynostemma pentaphyllum, cortex phellodendri, dandelions, cornus officinalis, radix rehmanniae preparata, herba portulacae, herba houttuyniae, licorice root and stevia rebaudiana as raw materials and have the effects of reducing blood lipid and blood pressure, improving organism immunity, beautifying the face and clearing away toxins, resisting fatigue and the like. The fine dried noodles contain rich functional activated substances such as suaeda salsa and amino acid, polypeptides, water-soluble dietary fibers, ferulic acid, active polysaccharides, saponin and flavone in the Chinese herbal medicines. The fine fried noodles have the advantages that compatibility of suaeda salsa and the Chinese herbal medicines is scientific, functional components in the Chinese herbal medicines are extracted through the technologies including ultrasonic secondary crushing, enzymolysis combined compound microorganism degradation and microwave assisted extraction method, the content of organic selenium in the product is increased, the nutritional healthy functions of the product are remarkably improved, and market prospects are wide.

The present invention discloses a production method of functional Chinese wolfberry fruit enzyme and product thereof. The production method includes pulping Chinese wolfberry fruits, conducting enzymatic hydrolysis, adjusting the solid content and pH value, sterilizing, inoculating probiotics and fermenting, conducting centrifugal separation, drying the thick slurry to obtain the Chinese wolfberry fruit enzyme powder, continuously inoculating the clear juice with probiotics and fermenting to obtain the Chinese wolfberry fruit enzyme stock solution, and after-ripening to obtain the Chinese wolfberry fruit enzymes. And the enzymes obtained can be used to produce other Chinese wolfberry fruit enzyme products including Chinese wolfberry fruit enzyme beverage, Chinese wolfberry fruit enzyme powder, effervescent tablets, chewable tablets, buccal tablets, granules, capsules, etc. The products have efficacies of clearing heat and toxins, replenishing blood, improving eyesight, lowering blood lipids and losing weight, improving body oxidation resistance, regulating balance of intestinal floras, enhancing immunity, promoting beauty, facilitating sleep, and preventing aging.

The present invention relates to a preparation method of medicine for reducing blood-lipid-Reshufatadine compound. Said method uses side chain aldehyde compound and triphenyl phosphorus ylide reagent compound and makes them undergo the condensation reaction so as to obtain Reshufatadine compound with high yield. Said invention also provides its key intermediate compound.

A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment, control or prevention of obesity, non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, vascular restenosis, inflammation, and other PPAR gamma mediated diseases, disorders and conditions.

The invention discloses a health-care noodle with functions of lowering pressure, blood lipid and sugar and softening blood vessel. The health-care noodle comprises the following materials in parts by weight: 60-80 parts of flour, 4-8 parts of gynostemma pentaphyllum, 3-5 parts of gingko leaves, 2-4 parts of polygonum multiflorum, 3-4 parts of haw, 2-3 parts of chrysanthemum, 1-3 parts of medlar, 5-10 parts of black fungus, 5-10 parts of mushroom and 2-6 parts of onion. The product has excellent improvement effects for patients suffering from hypertension, hyperglycemia and hyperlipoidemia, persons with poor sleep and endocrinopathy and in fatigue state for a long time, heart cerebrovascular sufferers and sub-health persons and better preventive treatment effects for arteriosclerosis, hypertension and coronary heart disease and can enhance disease-resistant abilities. The invention increases new noodle variety and ensures that the traditional noodle is more nutritive without any side effect.

The invention relates to a euphausia superba oil microcapsule capable of enhancing a blood lipid reducing effect and a preparation method thereof. The euphausia superba oil microcapsule prepared through the preparation method provided by the invention is high in embedding rate; after euphausia superba oil is embedded to be prepared into the microcapsule, the euphausia superba oil takes the shape of solid powder, so that the euphausia superba oil is convenient to store, process and use. An excellent raw material is provided for food and health food, and euphausia superba oil application product forms are broadened.

A novel compound of the formula:wherein ring Q is an optionally substituted pyridine ring;One of R0, R1 and R2 is -Y0-Z0, and the other tow groups are a hydrogen, a halogen, an optionally substituted hydroxy group, a hydrocarbon group that may be an optionally substituted hydrocarbon group or an acyl group;Y0 is a bond or an optionally substituted bivalent hydrocarbon group;Z0 is a basic group which may be bonded via oxygen, nitrogen, -CO-, -CS-, -SO2N(R3)- (where R3 is hydrogen or an optionally substituted hydrocarbon group), or S(O)n (wherein n is to 0, 1 or 2);......... is a single bond or a double bond, or a salt thereof, which has an excellent LDL receptor up-regulating, blood-lipids lowering, blood-sugar lowering and diabetic complication-ameliorating activity.

The invention relates to the field of processing of aquatic foods and specifically discloses a making method of an abalone can and the abalone can prepared by the method. The making method of the abalone can disclosed by the invention comprises the steps of making abalone meat, performing color fixation treatment on the abalone meat, preparing broth, canning, exhausting, sealing, sterilizing and the like, and the color fixation treatment method of the abalone meat is as follows: putting the made abalone meat into a traditional Chinese medicine extract solution at the temperature of 70-90 DEG C for soaking for 10-20min. The traditional Chinese medicine extract solution used in the making method is extracted by the inventor from fragrant solomonseal rhizome, honeysuckle flower, dark plum fruit and liquorice root, the traditional Chinese medicine extract solution contains natural color fixation components, and the abalone can made after putting the abalone meat into the traditional Chinese medicine extract solution for soaking treatment is yellow and bright in color and luster, so that the problem that the appearance of the abalone meat in the abalone can is gray and dark in color and luster is solved. In addition, the traditional Chinese medicine extract solution can also be added into the abalone can with the broth, so that the abalone can has the effects of reducing blood lipids, reducing blood pressure, improving immunity and the like.

The invention provides a food convenient to eat and balanced in nutrition. The food is prepared from the following ingredients in percentage by weight: 20%-70% of coarse cereal ingredients, 5%-60% of vegetable ingredients, 2%-20% of nut ingredients and 0.1%-8% of flavoring ingredients. Through optimization, the food disclosed by the invention can be applied to ordinary crowds including but not limited to old people, children, women and the like. Through the optimization of the formula, the food disclosed by the invention can be applied to special crowds including but not limited to crowds with obesity, crowds with high blood lipid, crowds with high blood sugar and crowds with high uric acid. According to the food and the preparation method thereof disclosed by the invention, natural food raw materials are used and are processed by a modern method, so that the nutrition and the flavor of the raw materials are maximumly reserved, no pigments, no preservatives, no stabilizing agents and the like are added, and the food is healthy and safe. The food disclosed by the invention is powdered, and after the food is brewed, the brewed food can be eaten, so that the food is convenient to eat and has a high application value. The method disclosed by the invention is simple and convenient to operate and suitable for industrial production, and has great economic benefits and social benefits.

A composition is provided which contains policosanol and chromium and / or chromium salts and which may be used for treating, preventing and or reducing metabolic syndrome, hypercholesterolemia and hypoglycemia related diseases, total cholesterol, LDL-cholesterol, LDL / HDL ratio, triglycerides, coronary heart disease (heart attacks and strokes), inflammation, deep-vein thrombosis, immunoregulatory diseases, cardiovascular diseases, obesity, insulin resistance, dyslipidemia, raised blood pressure, fatigue, premenstrual syndrome, anxiety, depression and / or neurodegenerative disorders, and / or raising HDL cholesterol and / or lean body mass in humans and animals. The method comprises administering policosanol and chromium and / or chromium salts which together effectively lower blood glucose levels and lower the LDL / HDL cholesterol ratio. Typically, the administered composition includes about 0.1-10:1 parts by weight of policosanol to chromium and / or chromium salts.

The invention discloses a method for preparing Kefir sour milk which comprises water, sugar and sour milk prepared from the fermentation of two different Kefir grains; the preparing method comprises the follow steps: 1. raw milk is sterilized and then cooled to the temperature of 20 DEG C to 30 DEG C; 2. the two different Kefir grains are activated and cultured separately; 3. the activated and cultured Kefir grains with inoculum size of 2 percent to 5 percen are respectively inoculated to the sterilized raw milk; 4. the raw milk is fermented for 15 hours to 24 hours at the temperature of 20 DEG C to 30 DEG C; 5. the Kefir grains are filtered out to obtain two filtrates which are fermentation agents; 6. the two fermentation agents are mixed; 7. the mixed fermentation agents with the inoculum size of 2 percent to 5 percent are inoculated to the sterilized original milks and then fermented at the variable temperature ranging from 20 DEG C to 45 DEG C for 4 hours to 6 hours; and 8. the fermented milk are blended, homogenized and canned. With the adoption of the fermentation agents for fermenting at the variable temperature, the flavor of Kefir milk is well improved. The ferment time of the product is short, the yeasts in the mixed fermentation agents are more stable and the difference between flavors of Kefir sour milk prepared in different batches is small. The product has health-care functions of regulating beneficial bacteria in intestinal canals, lowering blood lipids, resisting tumors and the like, thus being a low-cost functional beverage.

The present invention provides a mulberry leaf health-care jelly with high nutritive value, unique flavour and several health-care effects of reducing blood-lipid, reducing blood pressure and reducing blood sugar. Its formula composition includes (by wt%) 4.5-6% of mulberry leaf extract, 8-10% of white granular sugar, 10-13% of honey, 0.5-0.7% of carragheenin, 0.04% of essence, 0.15% of citric acid and adding water to 100%. Besides, said invention also provides its preparation method and concrete steps.

The invention discloses a traditional Chinese medicine polyester fiber, which comprises polyester fiber and traditional Chinese medicine powder, which are mixed according to the ratio of 90-95 parts of polyester fiber and 5-10 parts of superfine Chinese medicine powder. The preparation method includes main processes such as grinding, mixing, stirring, defoaming treatment and the like. Among them, Chinese medicine materials choose wolfberry, cassia seed, ginkgo leaf and honeysuckle. Lycium barbarum can promote blood circulation and prevent arteriosclerosis. Cassia seed can treat constipation, hyperlipidemia, and high blood pressure. Ginkgo leaf can reduce blood cholesterol levels in the human body and increase blood vessel permeability and elasticity. , honeysuckle can clear blood poison, reduce blood fat. The invention mixes four kinds of traditional Chinese medicine powders with the polyester fibers, so that the traditional Chinese medicine powders are uniformly distributed inside the fibers, thereby reducing high blood pressure, high blood sugar and high blood lipids.

The invention discloses an instant senecio cineraria tea cream, which is prepared through the following processes of (1) crushing air-dried senecio cineraria; (2) adding the crushed senecio cineraria into water, wherein the mass ratio of feed liquid is 1: (8-12); and soaking and extracting for 1-3 times at the temperature of 35-50 DEG C; and (3) filtering soak extract obtained by the step (2), concentrating and vacuum drying the filter liquor, and crushing to obtain the instant senecio cineraria tea cream. According to the preparing process, the defect that natural components of the senecio cineraria are damaged and run off due to conventional boiling is overcome, and no additive is needed in the preparing process, so that the obtained instant senecio cineraria tea cream has milder and thicker taste, is safer to drink, is convenient to use and carry, and has the health-care efficacies of reducing blood press, lowering blood lipid, regulating blood sugar, suppressing tumor, defying age and the like.

The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and / or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.

The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.