The invention discloses a 15MnNiDR low alloy steel plate for a low temperature pressure vessel. According to the invention, the 15MnNiDR low alloy steel plate is prepared by smelting and rolling nine alloy elements of Fe, C, Si, Mn, Ni, V, Nb, Ti and Als; through reasonable and strict control of the production processes of KR molten iron pretreatment, converter smelting, LF furnace refining, vacuum degassing treatment, continuous casting, heating, rolling, ACC laminar cooling, normalizing and the like, large scale industrial production of medium and heavy plates used for low temperature pressure vessels is realized, and all the performance of the medium and heavy plates reaches JB / T47030 standard, according with demands for low alloy steel plates in development of the industry of low temperature pressure vessels in China.