488 results about "Lactone Compound" patented technology

The invention discloses an eremophilane lactone compound with chemical name as 3beta-chiretta acyloxy group-eremophile-7(11)-alkylene-12, 8beta-lactone-14-acid, which can inhibit the biological activity of HL-60, CNE, KB, Hela and P338D1.

A nail lacquer for the treatment or prevention of fungal infections, such as, onychomycosis, includes fungicidally effective amount of ciclopirox, econazole, or other antifungal agent in a compatible film-forming lacquer vehicle which includes a water-insoluble film-forming polymer; pentadecalactone, or similar cyclic lactone compound or derivative thereof, and volatile solvent. The pentadecalactone functions as a plasticizer for the film-forming polymer and as a penetration enhancer for the antifungal agent. The composition, when applied to the nails provides a hard, clear, water-resistant film containing the antifungal agent. The compositions are used for the treatment of onychomycosis.

The present invention is directed to a polyester resin for use in a coating composition. The polyester resin is the reaction product of a first compound comprising a plurality of hydroxyl groups, a lactone compound, a carboxylic acid anhydride, an epoxy compound having at least one epoxy group, and a carbamate compound. The present invention is also directed to a coating composition including the polyester resin and to a method of preparing the resin.

This invention provides a process for producing a macrocyclic lactone compound, which comprises cultivating Actinoplanes sp. FERM BP-3832, in the presence of L-proline, L-hydroxyproline or L-nipecotic acid, and then isolating a macrocylic lactone compound from the fermentation broth. The compounds produced by this process include a compound of the following formula:The present invention also relates to a pharmaceutical composition comprising the same, which is useful as immunosuppressive, antimycotic, antitumor agent or the like.

Disclosed is a nonaqueous electrolyte solution containing a sultone compound represented by the Formula 1 below (wherein R₁ to R₄ respectively represent a hydrogen, a fluorine, a hydrocarbon group with 1 to 12 carbon atoms that may contain fluorine atom(s), n represents an integer of 0 to 3, and when n is 2 or 3, the two or three R₃ groups are independent from each other and the two or three R₄ groups are independent from each other), and an ethylene carbonate having a hydrogen atom substituted by a fluorine atom. Also disclosed is a lithium secondary battery employing the nonaqueous electrolyte solution. This nonaqueous electrolyte solution does not cause an increase in the internal resistance of a nonaqueous electrochemical device and improves the lifespan characteristics of the device. The lithium secondary battery containing the nonaqueous electrolyte solution exhibits greatly improved cycle charge/discharge characteristics at high temperature, and has excellent charge/discharge load characteristics.

A nonaqueous electrolyte solution for secondary batteries which is an electrolyte solution for secondary batteries obtained by dissolving a lithium salt in a nonaqueous solvent, wherein the nonaqueous solvent is a solvent mainly comprising a lactone compound and the content of hydroxy carboxylic acids in the electrolyte solution is 1 mmol/kg or lower and a secondary battery employing the same are excellent in high-temperature storage characteristics, cycle characteristics, and capacity retention characteristics and in various cell characteristics in a wide temperature range and safety such as firing properties.

The present invention generally relates to refreshing, soothing, and cooling compounds that affect sensory processes. More particularly, the present invention pertains to certain N-alkylcarbonyl-amino acid ester as described herein; compositions and articles comprising such compounds; and methods of treatment, for example, methods of increasing alertness, and decreasing fatigue or sleepiness, and alleviating ocular discomforts of irritation, itch, and pain.

Antimicrobial ketolide compounds are provided having the formula (A):

as well as pharmaceutically acceptable salts, esters or prodrugs thereof, pharmaceutical compositions comprising such compounds, methods of treating bacterial infections by the administration of such compounds, and processes for the preparation of the compounds.

The invention relates to electrolyte solution which can improve the swelling of a lithium ion battery; the electrolyte solution for improving the swelling of the lithium ion battery comprises three types of components: (1) lithium salt; (2) composite organic solvent of carbonate ester and cyclic lactone compounds; and (3) composite additive; the molar concentration of lithium salt in the electrolyte solution is 0.01 to 2 mol/L; the mass percentage of the composite additive in the electrolyte solution is 0.01 percent to 5 percents; in the lithium salt, one or more of the following substances coexist: LiBF4, LiN (CF3SO2) 2, LiC4F9SO3, LiN (CxF2x+1SO2) (CyF2y+1SO2) (x and y are natural numbers), LiB (C2O4) 2 or LiBF2C2O4. According to the invention, through the composition design of the electrolyte solution and the comprehensive application of composite organic solvent of carbonate ester and cyclic lactone compounds and the composite additive, the reactivity with a high nickel positive pole material is reduced, the swelling problem of a secondary lithium ion battery based on the high nickel positive pole material when in high-temperature storage is greatly solved, and the electrochemical properties of the lithium ion battery can be well displayed.

Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.

Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.

The invention provides an ink composition for ink-jet printing which does not cause clogging of nozzles of an ink-jet printer during printing, to thereby provide a print of desired printing quality; which ensures an appropriate drying rate of printed images; and which attains excellent color development. The ink composition for ink-jet printing, containing a pigment, a binder resin, a pigment dispersant, and a solvent, wherein the solvent is formed of (1) at least one glycol ether and at least one of a lactone compound and 2-pyrrolidone, or (2) at least one glycol ether acetate and at least one of cyclohexane and isophorone.

The invention discloses a celastrus angulatus and cnidium lactone compounded pesticide which consists of the following raw materials in parts by weight: 0.1-5 parts of celastrus angulatus, 0.1-5 parts of cnidium lactone, 5-15 parts of solvent, 5-15 parts of emulsifier, 1-6 parts of dispersant, 0.5-2 parts of antioxidant, 0.5-1 part of stabilizer, 0.5-10 parts of penetrant, 1-10 parts of anti-freezing agent, 1-3 parts of antifoaming agent and the balance of bamboo vinegar liquid or wood vinegar liquid based on 100 parts. The pesticide is prepared by six steps of filtration of bamboo (wood) vinegar liquid, preparation of an oil phase, preparation of a water phase, preparation of a mixed solution, preparation of pesticidal suspension emulsion and the like, is mainly used for preventing pear gall midge, shows an obvious synergistic effect, and realizes a good field control effect. The pesticide disclosed by the invention prevents drug resistance of pests after long-time use, can be automatically degraded, is safe and efficient to use, avoids pollution, and has low cost and good persistence.

The invention discloses pentacyclic triterpene-13,28-lactones with antineoplastic activity, shown as a general formula I, or pharmaceutically acceptable salts thereof as well as a preparation method and medical application thereof, belonging to the field of biological medicines. The preparation method of the compounds, provided by the invention, has the advantages of mild reaction conditions, simplicity in operation, higher yield as well as strong practicability and structural universality. Shown by a pharmacologic test result, the compounds provided by the invention have favorable antineoplastic activity and can be applied as an antineoplastic drug in clinic.

The thermosensitive imaging material can be prepared by using 2,2-diphenyl-2-phenolic group acetate derivant as midbody of soluble promotion-resistance compound to carry on addition reaction with olefine ether compound of vinyl diethyl ether and dihydropyran to obtain active ester ether compound or lactone compound containing active ether being used as soluble promotion-resistance compound having ability of high soluble resistance before acidolysis and high soluble promotion ability after acidolysis; and mixing this soluble promotino-resistance compound with linear phenol resin having acidolysis soluble promotion performance, infrared obsorption dye and thermolysis type of acid producing source in proper ratio.

The ester ether compound with high acidolysis activity is synthesized through the reaction between benzil acid (2,2-diphenyl glycolic acid) and phenols, each of which has at residual active point in its benzene ring, in the presence of p-toluene sulfonic-acid catalyst in 0.1-2 % and methyl benzene, dimethyl benzene and other benzene compound as solvent to synthesize a serial addition compound of benzil acid and phenols which may be further dewatered to produce lactone compound; and the etherification of the said addition compound or the lactone compound the ether compound, such as vinyl ethylether, dihydropyran, dihydrofuran, dihyidropyrrole, etc. at below 70 deg.c. The ester ether compound may be used as photothermal imaging information record material.

The present invention relates to novel first to fourth lactone compounds. The first lactone compound is represented by the formula (1),

in the formula, X represents CH₂, CH₂CH₂, O, S or NR¹, and R¹ represents hydrogen atom, a straight-chain, branched or cyclic alkyl group of a carbon number of 1-10. Hydrogen(s) of the alkyl group may partially or entirely be replaced with fluorine atom(s). Furthermore, a part of the alkyl group may contain an atomic group containing oxygen atom, sulfur atom, nitrogen atom, carbon-carbon double bond, carbonyl group, hydroxy group or carboxyl group.

The present invention relates to a new-type high-effective safety medicine-ginkgo leaf total lactone for curing depression. It is a terpene lactone extracted from ginkgo biloba. L or other portions of said plant, such as ginkgo nut, ginkgo root bark and ginkgo twing, in which five terpene lactone compounds of bilobalide A, bilobalide B, bilobalide C, bilobalide J and bilobalide are mainly contained.

A ball 2 has, in a ball surface layer area, an aroma layer 16 including a scent component. The aroma layer 16 is provided locally. The aroma layer 16 may be provided on the entire surface. The scent component is preferably at least one member selected from the group consisting of terpenes, ester compounds, aromatic compounds, ether compounds, aldehyde compounds, alcohol compounds, natural essential oils, hydrocarbons, ketone compounds, lactone compounds, and nitrogen-containing compounds. A perfume-material-encapsulating microcapsule may be used. The local aroma layer 16 is preferably provided by stamping. The aroma layer may be formed by spraying. A scent adsorbent may be further used. Preferably, the golf ball 2 is put into a package 20.

The present invention belongs to the field of catalysis technology, and is especially catalytic cyclic lactone polymerizing process. One or two cyclic lactone compounds as material are polymerized in toluene solvent in the presence of catalyst system comprising aluminum compound of amine or imine as catalyst and alkyl alcohol, alkyl phenol or organic acid as co-catalyst and in a pure argon washed container inside an oil bath at -20 to 250 deg.c for 1.5-600 min; and the reaction is terminated with and the polymer is dissolved in water solution of toluene. The catalyst system has high activity, and this results in low polymerization temperature, short reaction period and high yield. The product has high optical purity and high and controllable molecular weight, and the polymerization may be a solvent one, one bulk one, etc.