98 results about "Glucosamine hcl" patented technology

A topical skin rejuvenation preparation to relieve wrinkles, increase the skin's natural production of hyaluronic acid, reverse the lack of suppleness, hydrate from within, erase spider veins, reduce varicose veins, lighten aging dark blotches (“liver spots”/Lentigos, Senile Lentigines), decrease acne, and reduce under eye puffiness includes Glucosamine (2-amino-2-deoxy-alpha-D-glucose), a hexosamine (6 carbon amino sugar), including its derivative and precursor compounds: Glucosamine Sulfate, Glucosamine Hydrochloride, Glucose-6-Phosphate, Acetyl Glucosamine, Fructose-6-phosphate, Glucosamine-6-Phosphate, to increase production of Hyaluronic acid and collagen from Glucosamine Sulfate, its precursors and derivatives and to increase skin muscle tone by Dimethylaminoethanol (DMAE) while over coming deficiency it creates in each cell's production of PhosphatidylCholine, whose deficiency damages cell membranes, as well as mitochondrial and lysosome membranes.

An animal toy containing food having a first portion with food delivery means integrated therein adapted to securely house solid food treats, including a nutritional pet supplement, to be removed by the animal during play or through chewing action, and a second side with a plurality of gum stimulation teeth integrated within and projecting therefrom that act to massage the gums of the animal. Food delivery means may be provided as a plurality of cavities integrated within the first portion (and optionally, the second portion), preferably having a grooved or threaded interior for securely holding food pieces securely therein. Alternatively, the food delivery means is provided as a food portion composing the first portion. A pet supplement may be utilized, including joint preserving and joint rebuilding compositions comprising chicken collagen type II, glucosamine hydrochloride and chondroitin sulfate, a vitamin composition comprising vitamins C, D and K, a mineral composition comprising calcium, magnesium, zinc, copper, manganese and boron, a herbal anti-oxidant cofactor blend comprising citrus bioflavonoids, red grapes anthocyanins, turmeric rhizome, boswellia resin and fennel seed.

The invention discloses a health-care food with functions of improving skin moisture and reinforcing immunity. The health-care food comprises the following components in percentage by weight: 1.0 to 80.0 percent of collagen peptide powder, 0.1 to 40.0 percent of glucosamine, 0.1 to 30.0 percent of aloe extract, 0.1 to 50.0 percent of vitamin C (ascorbic acid), and 0.0 to 90.0 percent of auxiliarymaterials. The health-care food can be made into tablets, powder, particles, hard capsules, soft capsules, oral liquids and other oral preparations with various flavors. By virtue of a scientific formula, the raw materials with exact efficacies are compatible reasonably, the collagen peptide powder, the glucosamine, the aloe extract and the vitamin C (ascorbic acid) are selected as main raw materials, and the corresponding auxiliary materials can be selected according to different oral preparations. Furthermore, the selection, purchase, preparation and other aspects of the raw materials are completely operated according to related regulations of health-care foods, so the advancement and stability of the product are ensured; and the health-care food is safe, efficient and stable, and has controllable quality by adopting a modern preparation process matched with a strict quality control method. Toxicological safety tests and function tests prove that the health-care food can be used foreffectively improving the human skin moisture and reinforcing the human body immunity.

A health-care food for increasing human bone density is proportionally prepared from shark cartilage powder, Ca supplement, VD, epimedium, aminoglucose D-hydrochloride, and chondroitin sulfate. Its preparing process is also disclosed.

The invention belongs to the field of monosaccharide component analysis, and in particular relates to a method for detecting monosaccharide components in rainbow conk glycopeptide. The method comprises the following steps of: carrying out a test on HPLC (High Performance Liquid Chromatography) chromatographic condition and systematic compatibility; subsequently respectively absorbing a mixed reference solution and a test solution to be injected into the HPLC chromatographic instrument so as to obtain a chromatogram, wherein the reference solution is a 1phenyl-3-methyl-5-pyrazolone derivative solution of D-glucose, D-mannose, D-xylose, L-xylose, D-galactose, D-arabinose, D-hydrochloric acid glucosamine and L-rhamnose reference solutions; and the test solution is a 1-phenyl-3-methyl-5-pyrazolone derivative solution of a rainbow conk glycopeptide acid hydrolysis product. Polysaccharide peptide products such as rainbow conk glycopeptide, rainbow conk intracellular glycopeptide, rainbow conk extracellular glycopeptides and coriolus versicolor polysaccharide are distinguished by detecting the mole ratio of eight monosaccharide ingredients in a test sample, so that the quality and the curative effect of the rainbow conk glycopeptide are ensured.

The invention is an ingestible wellness one time daily dosage made of a large quantity of rapid absorbing glucosamine sulfate, glucosamine hydrochloride, and an n-acetyl glucosamine and combinations thereof, a large quantity of chondroitin sulfate, chondroitin hydrochloride and combinations thereof, a vasodialating sulfonate with at least one methyl group, and a buffer to reduce adverse symptoms from large amounts of glucosamine and chondroitin selected from the family of araliaceae and a B3 vitamin, wherein the invention is also a wellness beverage that involves a fluid combined with the ingestible wellness dosage.

A medicinal composition in the form of tablet, capsule, dispersing tablet, effervescent tablet, etc for treating the various osteoarthritides is prepared from aminoglucose hydrochloride, chondroitin sulfate and pharmacologically acceptable additives.

An effervescent tablet of compound aminoglucose sulfate/chondroitin sulfate for treating osteoarthritis is prepared from the aminoglucose sulfate, chondroitin sulfate (or its Na salt), and the pharmacologically acceptable additive. Its preparing process is also disclosed.

A topical composition for anti-aging and anti-UV damage treatment of the skin includes water soluble extract of Uncaria species, Arabidopsis thaliana extract, alpha lipoic acid, dimethylethanolamine, tetrahexyldecyl ascorbate, dimethyl sulfoxide, Glycyrrhiza Glabra (licorice) root extract, methylsulfonylmethane, phytosterols, D-ribose, tocotrienol, tocopherol, glucosamine hydrochloride, Pisum sativum extract; silicates of sodium, magnesium and aluminum, and a dermatologically acceptable liposomal delivery medium. The composition is useful in a method using it for anti-aging skin treatment effecting DNA repair in both the nucleus and the mitochondria. The topical composition can be applied on the skin of a person daily, and can also be applied in a dermal infusion treatment, with or without micro-dermal abrasion or skin suction. Topical application of the composition achieves effective reduction of pigmentation spots, degree of winkles, and improvement of skin color, tone and turgidity, particularly of the eyelid and facial areas.

The invention relates to an oral liquid composition for improving osteoarthritis and a preparation method thereof. Each milliliter of the composition comprises the following raw material components: 40-60mg of glucosamine hydrochloride, 30-50mg of chondroitin sulfate, 2-3mg of an organic acid, 1-3mg of an antiseptic, 0.2-0.4mg of a suspending aid, and a proper amount of a sweetener. The preparation method comprises the following steps: 1, dissolving chondroitin sulfate, the organic acid, the sweeter, the antiseptic, and the suspending aid in distilled water to obtain a solution, controlling the temperature of the solution at 30-50DEG C, accessing nitrogen for 10min, adding glucosamine hydrochloride, stirring to complete dissolving, determining the pH value and the content, filling nitrogen, bulking, capping, and sealing. By adopting the components and the method of the invention, a clear liquid preparation with a good stability and completely dissolved medicines can be prepared, and the taste of the preparation can be accepted by patients.

The invention discloses a glucosamine gel, comprising the following components in percentage by weight: 0.25-5.0 percent of glucosamine hydrochloride or glucosamine sulfate (in the terms of glucosamine), 0.8-4.0 percent of matrix, 25.0-40.0 percent of moisturizer, 1-10.0 percent of skin penetration enhancer, 0-2.0 percent of preservative in which zero is unavailable, 0-6.0 percent of solubilizer in which zero is unavailable, 0-2.0 percent of antioxidant in which zero is unavailable, and the balance of water. The preparation method of the glucosamine gel comprises the following steps of: dissolving glucosamine hydrochloride or glucosamine sulfate in water, adding the other ingredients and stirring till the glucosamine hydrochloride or glucosamine sulfate is dispersed uniformly; regulating a pH value to be 6.0-8.0 and adding water to the total amount; and uniformly stirring to obtain the glucosamine gel. More than 60 percent of glucosamine within 6 hours is released and the glucosamine gel plays roles in administrating medicine at regular point of time and rapidly taking into effect.

The invention discloses a novel preparation method of glucosamine sulfate, and belongs to the field of monosaccharide preparation methods. The novel preparation method adopts glucosamine hydrochloride as a raw material and comprises the following steps of treating a glucosamine hydrochloride aqueous solution by a strongly basic anion exchange resin to remove chloridions to obtain glucosamine; neutralizing the glucosamine by a sulfuric acid solution to obtain glucosamine sulfate; and drying the glucosamine sulfate to obtain a glucosamine sulfate preparation without sodium chloride. Specifically, the steps comprises 1) treating 1-25% (W/V) of the glucosamine hydrochloride aqueous solution by the pre-washed strongly basic anion exchange resin column to remove chloridions, 2) collecting effluent liquid obtained from the step 1), 3) adding 20-90% (W/W) of a sulfuric acid solution into the effluent liquid to obtain a glucosamine sulfate aqueous solution by neutralization, wherein a pH value of the glucosamine sulfate aqueous solution is in a range of 3.5 to 5.0; and 4) carrying out a freeze drying process on the glucosamine sulfate aqueous solution, or precipitating the glucosamine sulfate aqueous solution by an organic solvent and then carrying out vacuum drying to obtain a glucosamine sulfate preparation without sodium chloride. The novel preparation method has the advantages of simple process, low cost, less three-waste, and no pollution in production.

An injectable for injection into a spinal disc, and a method to treat a spinal disc with the injectable. The injectable consists essentially of chondroitin sulfate and glucosamine HCl buffered to a pH above about 6.0.

The invention relates to a chitosan-containing health composition to increase bone density and application thereof and belongs to the field of medicine. The chitosan-containing health composition to increase bone density is prepared from, by weight, 2-6 parts of chitosan, 10-50 parts of chondroitin sulfate, 10-50 parts of glucosamine hydrochloride, 10-20 parts of hyaluronic acid, 10-50 parts of milk minerals, 10-20 parts of colostrum basic protein, and 20-100 parts of collagen peptide. The components provide significant synergy to increase bone intensity and is suitable for popularization andapplication.

The invention relates to a quick and effective method for preparing glucosamine sulfate potassium chloride compound salt. The method is characterized by comprising the following steps of: treating anion resin by using 10 percent sulfuric acid solution, and preparing glucosamine hydrochloride solution; making the glucosamine hydrochloride solution pass through a column at a flow rate of 500mL/H, and performing metathesis to obtain glucosamine sulfate; slowly adding potassium chloride, performing metathesis with the obtained glucosamine sulfate solution, and performing reflux reaction in a molar ratio of 2:1 at the temperature of between 45 and 65DEG C for 24 hours; distilling the refluxed glucosamine sulfate potassium chloride solution under reduced pressure at the temperature of between 50 and 60DEG C until the distilled glucosamine sulfate potassium chloride solution is 40 to 50 percent of the total solution; and performing centrifugal dehydration and vacuum drying on the distilled glucosamine sulfate potassium chloride compound salt; and detecting and packaging the finished product. The quick and effective method overcomes defects that personnel are harmed and environment is polluted because an organic solvent is adopted for freeze drying in the prior art, and saves a large amount of operating cost.

The invention discloses a content detection method for glucosamine hydrochloride capsules. The method adopts a high performance liquid chromatograph and evaporative light-scattering detection method; a chromatographic column is a DIKMAC18 column of 5 micrometers with the specification of 200mm*4.6mm; a mobile phase consists of acetonitrile and water; the flow velocity of 0.1% of trifluoroacetic acid is 0.55-0.65ml/min; the temperature of the column is 30 DEG C; an Alltech ELSD 2000 detector is adopted; the temperature of a drift tube is 65-75 DEG C; and the pressure of an air pump is 0.24-0.28Mpa. A reference substance stock solution, a test solution and a negative auxiliary material solution are absorbed and then injected into a liquid chromatograph, a chromatogram map is recorded, a sample size log value is expressed as X, the corresponding peak area log value is expressed as Y, and linear fitting is conducted to obtain an equation of linear regression with the range of linearity between 0.8mg/ml to 1.2mg/ml.

The resent invention relates to a cream composition of glucosamine, including at least 10 wt %-15 wt % of glucosamine HCL, a methylsulfonylmethane component, a chondroitin component, and a cream base, wherein the composition promotes penetration of glucosamine from skin of affected area by synergistic interaction between components, in order to enhance absorption of human body.

A preparation for increasing the calcium absorption, which is provided by the invention, relates to a calcium supplement product, in particular to a preparation which can supplement calcium. The calcium supplement preparation of the invention is mainly prepared by main raw materials of calcium acetate, glucosamine hydrochloride, CPPs, extracts of epimedium and extracts of rhizoma drynariae, and is characterized in that the ratio of the main raw materials is 5 portions to 40 portions of calcium acetate, 1 portion to 20 portions of glucosamine hydrochloride, 0.5 portion to 3 portions of CPPs, 1 portion to 5 portions of extracts of epimedium, 1 portion to 5 portions of extracts of rhizoma drynariae and 0.1 portion to 25 portions of auxiliary material. The preparation of the invention can realize the effects of promoting calcium absorption, improving bone metabolism and bone nutrition and increasing the bone density.

The invention relates to the technical field of a health care product, and in particular provides a health care product capable of improving bones and joints and a preparation method of the health care product, wherein the health care product is mainly prepared from the following raw materials in parts by weight: as for active ingredients: 10-40 parts of calcium carbonate, 15-40 parts of chitosamine hydrochloride and 10-30 parts of chondroitin sulfate, and as for accessories: 0.1-1 part of glucose essence and 1-5 parts of a thin-film coating agent. The preparation method of the health care product capable of improving bones and joints comprises five steps, namely preparing powder, mixing, granulating, mixing materials and tabletting, and coating. The health care product provided by the invention is high in calcium content, good in effect and good in absorption, and the health care product, by supplementing calcium and promoting osteoblastic cell proliferation, has a function of enhancing bone density so as to take better effects on preventing and improving osteoporosis and improving life level of middle aged and elderly people; and the health care product is low in cost and is applicable to extensive popularization and application. The preparation method of the health care product provided by the invention is simple and efficient, high in active ingredient utilization rate and suitable for industrial popularization.