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180 results about "Digital microscopy" patented technology

A digital microscope is a variation of a traditional optical microscope that uses optics and a digital camera to output an image to a monitor, sometimes by means of software running on a computer.

Virtual microscope system

A virtual microscope system capable of obtaining a stained sample image and a statistical data of spectra in a short period of time is provided, the virtual microscope system includes an image obtaining unit for obtaining a stained sample image, a spectrum obtaining unit for obtaining a spectrum of the stained sample image, an optical path setting unit for setting an optical path of a light flux passed through the stained sample with respect to the image obtaining unit and the spectrum obtaining unit and a control unit for controlling to repeat obtaining the stained sample image by the image obtaining unit and obtaining the spectrum of the stained sample image by the spectrum obtaining unit in the observation field of the stained sample to create a virtual slide and a spectrum table of the stained sample.
Owner:EVIDENT CORP

Digital microscopy equipment with image acquisition, image analysis and network communication

A digital microscope comprises a housing with an image acquisition, an image processing, and a network communication (APC) module. The APC module can further comprise an image capture unit, coupled to an image sensor with a view to a subject on a slide, the image capture unit receiving an image of the subject. The APC module also comprises an image processing unit, coupled to the image capture unit, the image processing unit enhancing the image with classifications. Also, a network interface of the APC module, coupled to the image processing unit and to a network, the network interface sending the enhanced image across to the network and to receive control commands, the control commands associated with the view of the subject.
Owner:TEXAS INSTR INC

Full-automatic double-ccd photosensitive element digital microscope

ActiveCN102122066ATo achieve the purpose of intelligent screeningGuaranteed effectMicroscopesDigital imageOptical density
The invention discloses a full-automatic double-ccd (charge-coupled device) photosensitive element digital microscope, which is used for acquiring specimen image information by synchronously using a colored ccd photosensitive element and a black-and-white ccd photosensitive element so as to obtain a multifocal plane holographic three-dimensional image, synchronously outputting a specimen reading result according to nucleus integral optical density acquired by the black-and-white ccd photosensitive element, and finally outputting a specimen picture and text report. Additionally, the full-automatic double-ccd photosensitive element digital microscope comprises a slide uploading and unloading device and a horizontal migration clamping device for automatically changing the specimen slide, and then, the slide is located in three dimensions through a three-dimensional frame, so that the colored ccd photosensitive element and the black-and-white ccd photosensitive element can conveniently acquire the image information of the specimen. Thus, the full-automatic double-ccd photosensitive element digital microscope can be used for not only performing morphological observation on the specimen, but also taking digital images for a dyed tissue section so as to form the multi-focal plane holographic three-dimensional image, so that all the information of the cell can be observed in multiple layers and multiple focal planes, and accuracy of early diagnosis is greatly improved.
Owner:湖南港湾科学仪器有限公司

Abrasion in-situ measuring device based on digital image processing and method

ActiveCN102607977AIn-situ automated measurement of visual wearEnables continuous measurementInvestigating abrasion/wear resistanceDigital signal processingImaging processing
The invention relates to an abrasion in-situ measuring device based on digital image processing and a method. The device comprises a bottom plate, a horizontal displacement device, a vertical displacement device, a semi-arc slot transition plate, a support frame and a digital microscope; the bottom plate is used for supporting the total device in a connected manner and is fixed on a friction abrasion testing machine; the bottom plate is provided with the horizontal displacement device, the vertical displacement device and the semi-arc slot transition plate; the support frame is arranged on the right side of the transition plate and used for supporting the digital microscope; and by the aid of the abrasion in-situ measuring method based on digital image processing, the width value of an abrasion mark is obtained by means of treatments such as graying, binarization and the like for abrasion mark images and calculation of Radon conversion, gradient magnitude and the like. The abrasion mark image of a 'lower test piece' can be acquired accurately and fast, and furthermore, the abrasion image of an 'upper test piece' can be acquired conveniently. Besides, an abrasion mark image processing method is developed to analyze and obtain the width of the abrasion mark, and the in-situ measuring device can precisely measure abrasion marks.
Owner:西安永泽华正信息科技有限公司

Precision detection device and precision detection method of printing machine

The invention discloses a precision detection device of a printing machine, comprising an electronic detection meter and a computer and further comprising a detection printing plate, wherein the electronic detection meter is connected with the computer; the structure of a printing plate image printed on the detection printing plate is formed by combining a square frame with four sign markers arranged in the frame; the structure of the electronic detection meter is that an observation window, an image collection window and a digital microscope are arranged at one side inside a shell of a detector; an LED (Light-Emitting Diode) array light source is arranged at the other side inside the shell of the detector; and scattering glass is arranged between the LED array light source and the image collection window. The invention further discloses a detection method for utilizing the device to detect the precision of the printing machine, comprising the following steps of: printing special detection marks on the printing machine to obtain detected printing sheets; continuously reading 100 detected printing sheets to process analyzed image information data; and finally, obtaining paper transferring and conveying precision of the printing machine. The device and the method, disclosed by the invention, have high precision and automation degree.
Owner:XIAN UNIV OF TECH

Total internal reflection microscopy method and device based on free-form surface shaping

InactiveCN105807412AChange shadow sizeChange sizeMicroscopesTotal internal reflectionFree form
The invention discloses a total internal reflection microscopy device based on free-form surface shaping.The device comprises a light source and a line polarized light generating module, a free-form surface focusing module, a digital microscopy refection module, an optical enlargement transmission module and a fluorescence imaging module which are sequentially arranged along a light path, wherein the line polarized light generating module is used for converting light beams emitted by the light source into line polarized light; the free-form surface focusing module is used for converting the line polarized light into annular focused light; the digital microscopy refection module is used for selecting annular focused light reflected in an area; the optical enlargement transmission module is used for achieving total internal reflection illumination of the light beams; the fluorescence imaging module is used for exciting a sample to emit fluorescent light and collecting a fluorescent light signal image.The invention further discloses a total internal reflection microscopy method based on free-form surface shaping.According to the total internal reflection microscopy method and device based on free-form surface shaping, no mechanical vibration module is adopted, scanning is conducted more stably, and noise is lower; the utilization rate of laser energy is higher, and an imaging view field is more uniform; a DMD control controls scanning, the angle is more accurate, and it is helpful to achieve layered scanning and 3D image reconstruction.
Owner:ZHEJIANG UNIV

Oct surgical visualization system with macular contact lens

An ophthalmic visualization system can include an ocular lens positioned between a macular contact lens coupled to a procedure eye and a surgical microscope. The ocular lens can guide a light beam through the macular contact lens and into the procedure eye, and in combination with the macular contact lens generate an intermediate image of the procedure eye at an image plane between the procedure eye and the surgical microscope. The system can include a reduction lens positioned in the optical path between the surgical microscope and the ocular lens. The reduction lens and / or ocular lens can align a focus plane of the surgical microscope with the image plane. A method of visualizing a procedure eye in an ophthalmic procedure can include positioning an ocular lens and a reduction lens between a macular contact lens and a surgical microscope; and scanning the procedure eye with a light beam.
Owner:NOVARTIS AG

Ceramic matrix composite material high-temperature air environment substrate crack observation system and observation method

The invention discloses a ceramic matrix composite material high-temperature air environment substrate crack observation system and an observation method. The system comprises a digital microscope, atension testing device, a test sample, a heating device and a temperature controller, wherein the digital microscope comprises a platform main control system, a zoom lens, a lens base and a two-dimensional moving device; the test sample is horizontally mounted on the tension testing device; the tension testing device is horizontally arranged on the two-dimensional moving device; a rectangular transparent quartz glass plate is embedded above the heating device and is horizontally placed on a thermal insulating pad of the base of the tension testing device; the zoom lens is aligned to the centerof the test sample through the transparent quartz glass plate; the heating device is connected with the temperature controller. The tension testing device, the split type micro heating device and thedigital microscope are all independent individuals and are convenient to mount and dismount, and in an atmospheric environment, matrix cracks of the ceramic matrix composite material can be conveniently observed under the action of high-temperature air and stress loads.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS

Surgical microscopes using optical coherence tomography and related methods

Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam.
Owner:BIOPTIGEN

Biological digital microscope with double ccd (charge coupled device) light sensitive elements and photographic image processing method thereof

The invention discloses a biological digital microscope with double ccd (charge coupled device) light sensitive elements and a photographic image processing method thereof, wherein a colour ccd light sensitive element and a black and white ccd light sensitive element are used for collecting image information; the black and white ccd light sensitive element collects a gray scale and integrating optical density information of a specimen cell nucleus; the colour ccd light sensitive element collects a colour characteristic signal of a specimen image; the three-dimensional split joint of a specimen picture is performed by the gray scale of a specimen cell nucleus, the integrating optical density information and colour characteristic signal of a specimen image, so as to form a multi-focal plane holographic three-dimensional image; simultaneously, a film reading conclusion is output according to the integrating optical density information of a cell nucleus; finally a graphics context report of the specimen to be examined is output; therefore the biological digital microscope disclosed by the invention can perform conventional morphological observation for the specimen, as well as can perform digital photographing for the dyed DNA (deoxyribonucleic acid) for forming a multi-focal plane holographic three-dimensional image which is convenient for observing all the information of the cell in a multilayer and multi-focal plane mode; and the accuracy of early diagnosis is greatly improved.
Owner:南京福怡科技发展股份有限公司

Image quality assessment of microscopy images

Automated assessment of registration quality, focus, and area defects in sequentially acquired images, such as images acquired by a digital microscope, is disclosed. In one embodiment, acquired images are registered and whole-image defects are automatically detected based on a figure of merit generated by the registration process. In related implementations, area defects may be automatically detected by calculating correlations in localized image regions for images acquired in different imaging rounds.
Owner:LEICA MICROSYSTEMS CMS GMBH
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