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96 results about "Digital slide" patented technology

Image-based risk score-a prognostic predictor of survival and outcome from digital histopathology

The present invention relates to an image-based computer-aided prognosis (CAP) system and method that seeks to replicate the prognostic power of molecular assays in histopathology and pathological processes, including but not limited to cancer. Using only a tissue slide samples, a mechanism for digital slide scanning, and a computer, the present invention relates to an image-based CAP system and method which aims to overcome many of the drawbacks associated with prognostic molecular assays (e.g. Oncotype DX) including the high cost associated with the assay, limited laboratory facilities with specialized equipment, and length of time between biopsy and prognostic prediction.
Owner:RUTGERS THE STATE UNIV

Digital slide real-time scanning automatic focus system and method

The invention discloses a digital slide real-time scanning automatic focus system and method. The system comprises an optical microscope device, a dispersion prism, a focus controller, a displacement controller, a first imaging device and a second imaging device, wherein the focus controller adjusts the first imaging device and the second imaging device so that the first imaging device and the second imaging device can have a common view field. The dispersion prism splits a light path from the common view field into a first light path and a second light path. The first imaging device receives the first light path and forms a first image, and the second imaging device receives the second light path and forms a second image. The displacement controller estimates the position of a focus face of the next view field according to focus factor analyzing results of the two images of the current view field, and controls an object stage or an object lens to move to the next view field, so that the object stage or the object lens moves to the focus face of the next view field. According to the scheme, the digital slide real-time scanning automatic focus system is well compatible with a traditional optical microscope device, and repeated development is needless. Besides, the digital slide real-time scanning automatic focus system and method can obtain the best focus face quickly, and the obtained focus face is high in precision.
Owner:MOTIC CHINA GRP CO LTD

Second Opinion Network

ActiveUS20080292159A1Readily apparentFacilitates formal and information second opinionsMedical simulationMedical communicationDigital slideDigital image
Systems and methods are provided to facilitate consultations between a referral source (e.g., labs, pathologists and patients) and a consultant (e.g., pathologist, radiologist, or other digital image analyst). Links between the various referral sources and consultants are established through a scanning center via a data communication network such as the Internet. The referral source sends a slide to the scanning center where the corresponding digital slide is posted for review and analysis by the consultant. Upon completion of the analysis and report, a digital slide conference is conducted through the scanning center that provides a venue for direct communication regarding the consultation. The scanning center may also facilitate payment from the referral source to the consultant.
Owner:LEICA BIOSYST IMAGING

Digital slide real time scanning automatic focusing system and method thereof

The invention discloses a digital slide real time scanning automatic focusing system and a method thereof. The focusing system comprises an optical microscopic device, an optical spectral device, a focusing controller, a displacement controller, a first auxiliary imaging device and a second auxiliary imaging device, wherein a main imaging device, the first auxiliary imaging device and the second auxiliary imaging device are adjusted by the focusing controller to provide the main imaging device, the first auxiliary imaging device and the second auxiliary imaging device a common field of view, the spectral device is used for dividing a light path from the common field of view into a main light path, a first auxiliary light path and a second auxiliary light path, the focusing controller performs comparative analysis according to focusing factors of a first image, a second image and a main image, the displacement controller estimates the position of a focal plane of next field of view according to the analysis results of the focus controller for three images in the present field of view, and simultaneously the displacement controller controls an object holding stage or an object lens to move to the next field of view. By means of the scheme, compatibility with traditional optical microscopic devices is good, repeated development is not required, fast acquisition of an optimum focal plane is achieved, and accuracy of the acquired focal plane is high.
Owner:MOTIC CHINA GRP CO LTD

Automatic digital slide focusing device and method based on microscope

ActiveCN104181685AReduce scan timeOvercoming problems such as falling into shocksMicroscopesMountingsDigital slideMicroscope
The invention relates to an automatic digital slide focusing device and method based on a microscope. The automatic focusing device comprises the trinocular microscope and a computer, and the trinocular microscope is provided with an automatic objective table, a scanning ocular lens and a focusing turn button, wherein the automatic objective table can freely move along the axis-Z direction, the scanning ocular lens is provided with a digital camera that is connected with of the computer, and the focusing turn button plays the role of focusing. Clear visual images are obtained in the focusing method, namely an improved over-peaked step-variable hill-climbing focusing search method. The focusing device uses the high-precision automatic objective table, instruction is emitted by the computer, the automatic objective table is controlled to move along the axis-Z direction, the improved over-peaked step-variable hill-climbing focusing search method is used, the high-speed digital camera cooperates with the high-precision automatic objective table, the scanning time of the digital slide is reduced, influence of mechanical error on the focusing effect is reduced, the problem that a traditional step-fixed focusing method leads to oscillation is overcome, and the optimal focal plane can be rapidly and accurately determined.
Owner:杭州卓腾信息技术有限公司

Digital slide scanner and scanning focus number reducing method thereof

The invention provides a scanning focus number reducing method of a digital slide scanner. The method comprises the following steps: placing a slide on a scanning platform; scanning the slide to obtain a slide preview of the slide; adjusting the scanning area to be the entire slide; identifying foci; focusing to obtain focal lengths of foci; calculating focal planes according to the focal lengths. The mounting precision of a scanner slide mounting platform and an optical system can be effectively improved, so that a possibility is provided for clearly scanning ultra-large slides (the pixel value of a digital image can reach 100000 x 100000) with few foci. By dividing the parfocal area of the same color, the focus number is further reduced. According to the method provided by the invention, the scanning time can be entirely reduced by 20%.
Owner:KONFOONG BIOTECH INT
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