This invention openly carrying a foreign
gene active recombinant
protein carrier core area PEAII-HphA and preparation methods and application, but also take the initiative to open a foreign
gene carrying the recombinant
protein carrier
core gene fragment PEAII-HphA ; The initiative delivery exogenous
gene's reorganization
protein carrier is by guidance member - PEA
toxin cross membrane indexing area PEAII- ultra is addicted to the hot
Archaea histone HphA composition protein; Under the guidance member's guidance, on the carrier and the target
cell's
acceptor specificity union has manifested its target
tropism, lies between in the
acceptor leads passes PEA IIThe cross membrane transportation enters in
cell's to swallow the function traversing
cell membrane on own initiative, has manifested its initiative, raised the gene transportation efficiency effectively . HphA combination of
DNA, and a strong ability with the exogenous gene complexes formed in the
active transport carrier in the process, arrived at the exogenous gene, increasing its expression efficiency, cell non-toxic, more secure; Superior to the traditional vector and liposomes,it can be widely used in gene therapy and transgenic animal research.