57results about How to "Strong economic value" patented technology

The invention relates to olaparib and urea eutectic and a preparation method thereof and particularly provides a eutectic form A, an X-ray powder diffraction of the crystal form shows characteristic peaks at 17.4 DEG + / - 0.2 DEG, 20.7 DEG + / - 0.2 DEG and 10.5 DEG + / - 0.2 DEG of value 2theta.The eutectic has better stability, lower hygroscopicity and higher solubility than existing olaparib free base crystal forms and is of significant value to the optimization and development of its drugs in future.

Disclosed is a centralized control method for a precision machine room air-conditioner system. The method comprises the steps that (1) indoor temperature and the humidity are monitored in real time, and a mathematic model is adopted for starting one precision air conditioner once the temperature or the humidity exceeds the upper limit or the lower limit; (2) after a few periods of time, the temperature and the humidity are monitored again, and if the temperature and the humidity are within the stopping range, all the precision air conditioners are stopped; if the temperature and the humidity are not within the stopping range, the mathematic model is adopted for starting another precision air conditioner; (3) the step (2) is executed repeatedly until the temperature and the humidity are within the stopping range. According to the centralized control method, on the premise that safe and stable running of a machine room can be ensured, the starting and stopping frequency of one single air conditioner is reduced, the service life of the air-conditioner system is prolonged, the maintenance cost of the machine room is reduced, and the centralized control method has high economic value.

The invention relates to a novel crystal form and a preparation method of hemisuccinate of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-yl amino)-7H-pyrrolo[2,3-D]pyrimidine-6-carboxylic acid dimethylamide and a novel crystal form and a preparation method of monosuccinate. The novel crystal forms of hemisuccinate and monosuccinate of a compound represented by a formula (I) (shown in the specification) have the beneficial performance of good stability, relatively low hygroscopicity, process exploitability and tractability, are low in cost and have important values on the optimization and development of drugs in further, and the preparation methods are simple.

The present invention discloses a decision optimization method of multi-land seed selection based on combination optimization. Aiming at a multi-land seed selection decision problem, a multi-land grain seed selection decision model based on a combination optimization theory method is constructed to achieve decision optimization of multi-land seed selection. The method comprises the steps of: constructing a training sample set; obtaining key factors which influence a yield; constructing a neural network model and performing training; constructing a training test set; obtaining a yield prediction value and a variance of a parcel through the trained neural network model; constructing a multi-land grain seed selection decision optimization model based on combination optimization; and employinga decomposition algorithm to solve an optimal seed selection proportion to obtain the optimal varieties of the seeds and a usage proportion. The decision optimization method of multi-land seed selection based on combination optimization can perform analysis and optimization of grain plantation and seed selection, and can guide concrete land agriculture plantation and agriculture plantation planning; and moreover, the decision optimization method provides technical support for macroscopic agriculture policy or regional sales and a stocking strategy so as to have great economic and social values.

The invention relates to a novel crystal form of a JAK inhibitor and a preparation method thereof. The novel crystal form provided by the invention can be used for treating autoimmune diseases, especially rheumatoid arthritis. The novel crystal form provided by the invention has good stability, obvious process purification effect, and the solubility and moisture in conformity with the requirement of medicine usage. The preparation method of the novel crystal form is simple and low in cost, and is of great value to the optimization and development of the medicine in the future.

Disclosed are a co-crystal of olaparib and urea and a preparation method therefor. Specifically disclosed is a co-crystal form A, and an X-ray powder diffraction pattern of this crystal form has characteristic peaks at points where 2theta value is 17.4°±0.2°, 20.7°±0.2°, 10.5°±0.2°. The disclosed co-crystal has better stability, lower hygroscopicity and higher solubility as compared to existing olaparib free alkali crystal forms.

The invention discloses a centralized control method of a precise air conditioning system. The centralized control method comprises a temperature rise control method and a temperature reducing control method. The centralized control method of the precise air conditioning system has the following beneficial effects: on the basis of even indoor temperature distribution, arrangement of air conditioner at the same side of a machine room and a consistent space, the method establishes a mathematical relationship between the starting time of a single air conditioner and service life specific to a precise air conditioning system in the same one machine room scale, comprehensively considers the state of a plurality of precise air conditioners, and adjusts the opening and closing strategies at any time by taking the longest service life of the air conditioning system as a goal according to the change of the indoor temperature and humidity. On the basis of ensuring safe and stable operation of the machine room, the centralized control method, the centralized control method avoids the frequency start-stop of a single precise air conditioner, prolongs the service life of the air conditioning system, and saves the maintenance cost of the machine room; therefore, the centralized control method has strong economic value.

The invention relates to the polluted-environment phytoremediation technology, in particular to a method for repairing Pb-polychlorinated biphenyl combined pollution soil through halophytes kochia scoparia (L.) Schrad. According to the method, a large amount of Pb in the polluted soil is absorbed and collected through root systems of the halophytes kochia scoparia (L.) Schrad. and transported to the ground portions, polychlorinated biphenyl in the soil can be further degraded through the root systems and microorganisms of the halophytes, and the whole-plant halophytes are harvested after the halophytes grow for 90 days and duly handled, so that the large amount of Pb is collected from soil, and the polychlorinated biphenyl in the soil is degraded; as the halophytes are repeatedly planted and the process is repeated, the excess Pb and the excess polychlorinated biphenyl in the soil can be continuously removed till the content of the Pb and the content of the polychlorinated biphenyl in the soil meet the environmental safety standard. The method has the advantages that investment is small, the work amount is small, the physicochemical properties of the soil are not damaged, secondary pollution is avoided, and the environment can be beautified while the polluted soil is treated.

The invention discloses a new process for comprehensively recovering scandium in gas ash by using waste acid. The waste acid for scandium-contained gas ash is filtered after normal-pressure leaching I; solution obtained by filtering is neutralized by the scandium-contained gas ash after being reduced by reducing agent; obtained neutralized slag is leached at normal pressure by the waste acid; and extraction, back extraction, and precipitation by adopting oxalic acid are performed on the filtrate obtained by leaching to obtain scandium oxalate. The new process treats the gas ash through the waste acid, that is, wastes are used, high-value elements are recovered, and the economic value is high; and meanwhile, the process conditions are easy to realize, the scandium is enriched and recovered, metal such as zinc and iron in the gas ash is recovered, and the comprehensive resource utilization of the gas ash in a blast furnace is realized. The new process is simple in treatment method, obvious in effect and high in popularization significance.

The invention belongs to the technical field of an electric material and provides an anti-aging cable sheath material and a preparation method thereof. The cable sheath material comprises the following raw materials in parts by weight: 52-64 parts of modified polyurethane resin, 13-22 parts of chlorinated polyethylene, 7-22 parts of dibutyl maleate, 12-19 parts of organic nanometer montmorillonite, 2-5 parts of bocour blue, 2-5 parts of chlorinated paraffin, 1-4 parts of an anti-aging agent, 0.6-2.8 parts of a coupling agent, 1.3-3.4 parts of an ultraviolet light absorber and 1.6-2.9 parts of a plasticizer. The cable sheath material provided by the invention has an anti-aging property. The modified polyurethane resin is used as a main raw material, and the organic nanometer montmorillonite, bocour blue, chlorinated paraffin, anti-aging agent and ultraviolet light absorber are used as auxiliaries, so that the prepared cable sheath material has an excellent anti-aging property.

The invention discloses a method for recycling glyphosate from glyphosate mother liquor of IDA method. The method adopts the following steps: entering the glyphosate mother liquor of IDA method into a membrane concentration device after pre-treatment to obtain primary glyphosate concentrated liquor; adding alkali conditioning agent in the primary glyphosate concentrated liquor, and carrying out distillation, concentration and dehydration in an evaporator to obtain secondary glyphosate concentrated liquor; adding acid in the secondary glyphosate concentrated liquor for conditioning, crystallizing at normal temperature, filtering and washing with water to obtain glyphosate solid, and re-crystallizing the glyphosate solid to obtain glyphosate bulk drug. The method combines membrane method and evaporating concentration, so that the yield of glyphosate is high, rectificating is unnecessary, the production cost is lowered, energy consumption is saved, environment protection pressure is reduced, and higher economic value is obtained.

The invention relates to a crystal form of AHU377 as well as a preparation method and an application thereof. The novel crystal form is good in stability, low in hygroscopicity and remarkable in technological purification effect. The novel crystal form of the compound AHU377 represented in a formula (I) can be applied to preparation of an anti-heart-failure drug.

The invention provides a sodium salt of a phenylacetic acid compound as well as a crystalline form and preparation method of the sodium salt, a pharmaceutical composition containing the sodium salt, and a preparation form and a pharmaceutical application of the pharmaceutical composition. The compound represented by a formula I shown in the specification is a pharmaceutically active substance belonging to phenylacetic acid compounds. The sodium salt or crystalline form of the compound represented by the formula I has higher water solubility and physical and chemical stability, and has the advantages of a small dosage, a fast medicine effect and small toxic and side effects, and the pharmaceutical composition containing the sodium salt of the compound represented by the formula I obtained by alkali addition is widely used in the preparation of analgesic, antipyretic and anti-inflammatory drugs.

The invention discloses a phosphogypsum metal adsorption material and a preparation method thereof. The phosphogypsum metal adsorption material is prepared from raw materials including phosphogypsum,triethylene tetramine, tricyanogen chloride, epichlorohydrin, ferric chloride, fly ash and the like. A high-adsorption-amount raw material is obtained by carrying out calcination treatment on the phosphogypsum; nano iron oxide is synthesized by utilizing a water phase, and adsorption varieties of pollutants are increased; the adsorption efficiency on heavy metal is improved; then the raw materialis dissolved into a mixed solution system of the triethylene tetramine, the tricyanogen chloride and the like, so that a metal ion complexing functional group on the adsorption material is increased;furthermore, a cation group can have a flocculation effect on solid suspension matters, colloids and the like, so that the adsorption material is used for removing heavy metal ions, oil stain and thelike at the same time; the phosphogypsum metal adsorption material has the advantages of simple raw materials, relatively low production cost, good technology repeatability, high operability and capability of realizing amplified production, and has relatively high economic value.

The invention discloses a crystal form of alkynyl-containing compound salt and a preparation method and application of the crystal form. The invention specifically discloses a crystal form II of 3-((1H-pyrazole [3, 4-b] pyridine-5-substituted) ethynyl)-4-methyl-N-(4-((4-methylpiperazine-1-substituted) methyl)-3-(trifluoromethyl) phenyl) benzamide fumarate. The crystal form provided by the invention has good stability, and has important value for optimization and development of drugs.

The invention discloses a eutectic crystal of TAF (tenofovir alafenamide) and vanillic acid and a preparation method of the eutectic crystal. The eutectic crystal has the structural formula shown in the specification. In the eutectic crystal, the mole ratio of TAF to vanillic acid is 1:1. Besides, the invention also discloses the preparation method of the eutectic crystal and an application of theeutectic crystal. The provided eutectic crystal of TAF and vanillic acid has higher melting point, improved heat stability and improved moisture absorption, the sensitivity to the environment humidity and temperature is reduced in the preparation and storage process, the production and aftertreatment process of drugs is simplified, the material storage and quality control cost is reduced, and theeutectic crystal of TAF and vanillic acid has higher economic value and is more suitable for being used as a crude drug. Besides, the eutectic crystal displays good crystallinity and is easy to prepare and applicable to industrial large-scale production.

The invention discloses a crystal form I of an alkynyl-containing compound as well as a preparation method and application thereof. The invention particularly discloses a crystal form I of 3-((1H-pyrazole [3, 4-b] pyridine-5-substituted) ethynyl)-4-methyl-N-(4-((4-methylpiperazine-1-substituted) methyl)-3-(trifluoromethyl) phenyl) benzamide. The crystal form provided by the invention has good stability, and has important value for optimization and development of drugs.

The invention discloses a vanilline crystal form and a preparation method thereof. The vanilline crystal form is named a crystal form A. In an X-ray powder diffraction spectrum detected by using Cu-Kalpha radiation, characteristic peaks exit at the positions of 11.366, 11.740, 13.019, 13.894, 14.406, 17.187, 21.013, 21.685, 22.883, 23.778, 25.878, 26.59, 26.856, 28.638, 29.705+ / -0.2 <o> (2 theta). The invention also provides the preparation method of the vanilline crystal form A. The preparation method is simple and high in reproducibility; and the obtained vanilline crystal A is high in stability, high in purity and good in digesting performance, has no hygroscopicity, and is applicable to industrial production.

The invention relates to the technical field of artificial aggregates, in particular to an artificial aggregate and a preparation process thereof. The artificial aggregate comprises a mixture of an aggregate component A and an aggregate component B, the aggregate component A is prepared from the following raw materials: 30 to 40% of 128 epoxy resin, 5 to 10% of a reactive diluent, 35 to 55% of quartz powder, 1 to 3% of fumed silica, 5 to 10% of a pigment, 0.1 to 1% of a defoaming agent and 0.1 to 1% of a flatting agent; the aggregate component B is prepared from the following raw materials: 30 to 40% of methyl hexahydrophthalic anhydride and / or 30 to 40% of methyl tetrahydrophthalic anhydride, 5 to 10% of an accelerant, 35 to 55% of quartz powder, 1 to 3% of fumed silica, 0.1 to 1% of a defoaming agent and 0.1 to 1% of a flatting agent; and the raw materials are in percentage by weight. The product has the properties of being good in weather resistance, excellent in aging resistance, high in bonding strength, uniform in color sense, low in water absorption rate, capable of replacing various mineral materials and the like, large-scale popularization of the artificial aggregate is facilitated, and ore extraction can be reduced.

The invention provides a pregna-5, 7-diene-3, 20-diethylene glycol ketal crystal form and a preparation method thereof The crystal form provided by the invention is relatively stable under high temperature, high humidity and illumination, and can well avoid crystal transformation and product degradation in intermediate storage and subsequent use processes. The invention also provides a preparation method of the crystal form, and the method is simple, convenient, good in reproducibility and suitable for industrial production.

The invention relates to AHU377 crystal form and a preparation method and uses thereof and provides AHU377 crystal forms III and IV, good in stability, low in hygroscopicity, high in cleaning capacity, good in purifying effect and high in economic value.

The invention relates to a servo feeding paper tube cutting machine, and belongs to the technical field of paper tube cutting equipment. The paper tube cutting machine comprises a paper tube clampingand rotating mechanism, a servo feeding and cutting mechanism and a rack, wherein the paper tube clamping and rotating mechanism and the servo feeding and cutting mechanism are arranged on the rack. The servo feeding paper tube cutting machine is simple equipment, compact in structure and low in investment cost, can improve the paper tube cutting efficiency and the cutting plane flatness, reducesthe labor intensity of workers and the labor cost, has wide market application prospect, and has high economic value, high practical value and high popularization value.

The invention relates to phosphate of N-(3-(2-(4-(4-acetylpiperazine-1-yl)-2-methoxyphenylamino)-5-(trifluoromethyl)pyrimidine-4-yl-amino)phenyl)acrylamide), and a crystal form and a preparation method thereof. The phosphate of the compound as shown in a formula (I) which is described in the specification has favorable performance like good stability, low hygroscopicity and process developability and manageability; and the preparation method is simple and has low cost, so the method has an important value to optimization and development of the phosphate of the compound as a drug in the future.

The invention relates to a crystal form for treating melanoma and ovarian cancer and a preparation method of the crystal form, in particular to crystal forms of an orally-taken mitogen-activated protein kinase inhibitor and a preparation method of the crystal forms. The crystal form A and the crystal form B are good in stability and significant in process purification effect, and the solubility and hygroscopicity of the crystal form A and the crystal form B meet medication requirements. The preparation method of the crystal forms is simple and low in cost and has important value in optimization and development of the medicine in the future.

The invention relates to the technical field of tea production workshops, in particular to a storage box for tea production workshops, including a box frame, a number of storage boxes are installed on the front side wall of the box frame, and a box cover is installed on the upper side of the storage box. The front side wall of the storage box is equipped with a handle for opening the cover, and the cavity of the storage box is provided with a partitioned storage room. The bottom of the partitioned storage room is equipped with a positioning plate. A baffle is provided, a blower is installed on the inner side wall of the baffle, a rocker is installed on the front side wall of the blower, a lock nut is installed on the rotating shaft of the universal wheel, and a blower is installed in a storage box for the tea production workshop. The rocker at the baffle can be shaken, and the rocker can be used in conjunction with the blower. Every once in a while, when there is an odor in the storage box, the staff can shake the rocker regularly, and the ventilation system starts to operate, coordinating with each other to circulate the internal and external air , which reduces the work intensity of the staff and further improves the production efficiency.

The invention relates to crystal forms of phosphate, tartrate and citrate of (3beta)-17-(1H-benzimidazole-1-yl)androst-5,16-diene-3-ol and a preparation method of the compound. The crystal forms of phosphate, tartrate and citrate of a compound shown in a formula (I) have beneficial properties of high solubility, low hygroscopicity, good stability, simple technology and easiness for operation, are applicable to storage and industrial production and have important value on optimization and development of the medicine in future. The formula (I) is described in the specification.

The invention discloses a new process for comprehensively recovering scandium in gas ash by using waste acid. The waste acid for scandium-contained gas ash is filtered after normal-pressure leaching I; solution obtained by filtering is neutralized by the scandium-contained gas ash after being reduced by reducing agent; obtained neutralized slag is leached at normal pressure by the waste acid; and extraction, back extraction, and precipitation by adopting oxalic acid are performed on the filtrate obtained by leaching to obtain scandium oxalate. The new process treats the gas ash through the waste acid, that is, wastes are used, high-value elements are recovered, and the economic value is high; and meanwhile, the process conditions are easy to realize, the scandium is enriched and recovered, metal such as zinc and iron in the gas ash is recovered, and the comprehensive resource utilization of the gas ash in a blast furnace is realized. The new process is simple in treatment method, obvious in effect and high in popularization significance.

The invention discloses a crystal form of an aromatic ethylene derivative as well as a preparation method and application of the crystal form. The invention specifically discloses a crystal form A, a crystal form B and a crystal form C of a compound as shown in a formula I. The crystal form provided by the invention has good stability, is not easy to absorb moisture, is easy to prepare, and has important value for optimization and development of medicines.